View source for 2.8.1.6-RXN

[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=2.8.1.6-RXN 2.8.1.6-RXN] ==
* direction:
** LEFT-TO-RIGHT
* common name:
** biotin synthase
* ec number:
** [http://enzyme.expasy.org/EC/2.8.1.6 EC-2.8.1.6]
* Synonym(s):

== Reaction Formula ==
* With identifiers:
** 2 [[Reduced-2Fe-2S-Ferredoxins]][c] '''+''' 1 [[Sulfurated-Sulfur-Acceptors]][c] '''+''' 1 [[DETHIOBIOTIN]][c] '''+''' 2 [[S-ADENOSYLMETHIONINE]][c] '''=>''' 1 [[BIOTIN]][c] '''+''' 2 [[Oxidized-2Fe-2S-Ferredoxins]][c] '''+''' 1 [[Unsulfurated-Sulfur-Acceptors]][c] '''+''' 2 [[CH33ADO]][c] '''+''' 2 [[MET]][c]
* With common name(s):
** 2 a reduced [2Fe-2S] ferredoxin[c] '''+''' 1 a sulfurated [sulfur carrier][c] '''+''' 1 dethiobiotin[c] '''+''' 2 S-adenosyl-L-methionine[c] '''=>''' 1 biotin[c] '''+''' 2 an oxidized [2Fe-2S] ferredoxin[c] '''+''' 1 an unsulfurated [sulfur carrier][c] '''+''' 2 5'-deoxyadenosine[c] '''+''' 2 L-methionine[c]

== Genes associated with this reaction  ==
Genes have been associated with this reaction based on different elements listed below.
* Gene: [[Ec-24_000980]]
** Source: [[annotation-esiliculosus_genome]]
*** Assignment: GO-TERM
== Pathways  ==
* [[PWY0-1507]], biotin biosynthesis from 8-amino-7-oxononanoate I: [http://metacyc.org/META/NEW-IMAGE?object=PWY0-1507 PWY0-1507]
** '''3''' reactions found over '''3''' reactions in the full pathway
* [[PWY-7380]], biotin biosynthesis from 8-amino-7-oxononanoate II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7380 PWY-7380]
** '''2''' reactions found over '''3''' reactions in the full pathway
== Reconstruction information  ==
* Category: [[manual]]
** Source: [[manual-erythro]]
** Source: [[manual-sphingo361]]
** Source: [[manual-sphingo391]]
** Source: [[manual-hoflea]]
** Source: [[manual-roseov420]]
** Source: [[manual-imperaili]]
** Source: [[manual-roseov134]]
** Source: [[manual-marino]]
** Source: [[manual-bosea]]
* Category: [[annotation]]
** Source: [[annotation-esiliculosus_genome]]
*** Tool: [[pathwaytools]]
== External links  ==
* RHEA:
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=22060 22060]
* LIGAND-RXN:
** [http://www.genome.jp/dbget-bin/www_bget?R01078 R01078]
* UNIPROT:
** [http://www.uniprot.org/uniprot/Q9JRW7 Q9JRW7]
** [http://www.uniprot.org/uniprot/Q9PLZ3 Q9PLZ3]
** [http://www.uniprot.org/uniprot/P53557 P53557]
** [http://www.uniprot.org/uniprot/O67104 O67104]
** [http://www.uniprot.org/uniprot/P44987 P44987]
** [http://www.uniprot.org/uniprot/Q58692 Q58692]
** [http://www.uniprot.org/uniprot/P0A506 P0A506]
** [http://www.uniprot.org/uniprot/Q9Z6L5 Q9Z6L5]
** [http://www.uniprot.org/uniprot/Q9JUE3 Q9JUE3]
** [http://www.uniprot.org/uniprot/P46396 P46396]
** [http://www.uniprot.org/uniprot/Q47862 Q47862]
** [http://www.uniprot.org/uniprot/P19206 P19206]
** [http://www.uniprot.org/uniprot/P32451 P32451]
** [http://www.uniprot.org/uniprot/P54967 P54967]
** [http://www.uniprot.org/uniprot/P46715 P46715]
** [http://www.uniprot.org/uniprot/P73538 P73538]
** [http://www.uniprot.org/uniprot/P12996 P12996]
** [http://www.uniprot.org/uniprot/O59778 O59778]
{{#set: direction=LEFT-TO-RIGHT}}
{{#set: common name=biotin synthase}}
{{#set: ec number=EC-2.8.1.6}}
{{#set: gene associated=Ec-24_000980}}
{{#set: in pathway=PWY0-1507|PWY-7380}}
{{#set: reconstruction category=manual|annotation}}
{{#set: reconstruction source=annotation-esiliculosus_genome|manual-erythro|manual-sphingo361|manual-sphingo391|manual-hoflea|manual-roseov420|manual-imperaili|manual-roseov134|manual-marino|manual-bosea}}
{{#set: reconstruction tool=pathwaytools}}