QUINOPRIBOTRANS-RXN

Reaction QUINOPRIBOTRANS-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • nicotinate-nucleotide diphosphorylase (carboxylating)
• ec number:
  • EC-2.4.2.19
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 QUINOLINATE[c] + 2 PROTON[c] + 1 PRPP[c] => 1 NICOTINATE_NUCLEOTIDE[c] + 1 CARBON-DIOXIDE[c] + 1 PPI[c]
• With common name(s):
  • 1 quinolinate[c] + 2 H+[c] + 1 5-phospho-α-D-ribose 1-diphosphate[c] => 1 β-nicotinate D-ribonucleotide[c] + 1 CO2[c] + 1 diphosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Ec-27_002350
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-09_003390
  • Source: orthology-aragem
• Gene: Ec-05_000790
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM

Pathways

• PWY-5316, nicotine biosynthesis: PWY-5316
  • 3 reactions found over 9 reactions in the full pathway
• PWY-5653, NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde: PWY-5653
  • 4 reactions found over 4 reactions in the full pathway
• PYRIDNUCSYN-PWY, NAD biosynthesis I (from aspartate): PYRIDNUCSYN-PWY
  • 6 reactions found over 6 reactions in the full pathway
• PWY-7342, superpathway of nicotine biosynthesis: PWY-7342
  • 4 reactions found over 13 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-aragem
    • Tool: pantograph
• Category: manual
  • Source: manual-erythro
  • Source: manual-sphingo361
  • Source: manual-sphingo391
  • Source: manual-hoflea
  • Source: manual-rhizobi
  • Source: manual-imperaili
  • Source: manual-marino
  • Source: manual-bosea
• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 12733
• LIGAND-RXN:
  • R03348
• UNIPROT:
  • Q9JSX8
  • Q57916
  • P30011
  • P46714
  • Q15274
  • P77938