3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN

Reaction 3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • NADP-dependent 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain
• ec number:
  • EC-1.1.1.31
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 NAD[c] + 1 CPD-12175[c] => 1 CH3-MALONATE-S-ALD[c] + 1 PROTON[c] + 1 NADH[c]
• With common name(s):
  • 1 NAD+[c] + 1 (S)-3-hydroxy-isobutanoate[c] => 1 (S)-methylmalonate-semialdehyde[c] + 1 H+[c] + 1 NADH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Ec-14_006530
  • Source: orthology-aragem
• Gene: Ec-11_000140
  • Source: annotation-esiliculosus_genome
    • Assignment: EC-NUMBER

Pathways

• VALDEG-PWY, L-valine degradation I: VALDEG-PWY
  • 8 reactions found over 8 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-aragem
    • Tool: pantograph
• Category: manual
  • Source: manual-erythro
  • Source: manual-sphingo361
  • Source: manual-sphingo391
  • Source: manual-roseov420
  • Source: manual-rhizobi
  • Source: manual-hoflea
  • Source: manual-roseov134
  • Source: manual-marino
  • Source: manual-bosea
• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• LIGAND-RXN:
  • R02047
• UNIPROT:
  • P29266
  • P28811
  • Q8XAE4
  • Q55702
  • Q9XTI0