TIGLYLCOA-HYDROXY-RXN

Reaction TIGLYLCOA-HYDROXY-RXN

• direction:
  • REVERSIBLE
• common name:
  • Tiglyl-CoA hydratase
  • enoyl-Coenzyme A hydratase/3-hydroxyacyl Coenzyme A dehydrogenase
  • Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ
  • ClpP/crotonase-like domain
• ec number:
  • EC-4.2.1.17
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 2-METHYL-3-HYDROXY-BUTYRYL-COA[c] <=> 1 WATER[c] + 1 CPD-1083[c]
• With common name(s):
  • 1 (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA[c] <=> 1 H2O[c] + 1 (E)-2-methylcrotonoyl-CoA[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Ec-16_003560
  • Source: annotation-esiliculosus_genome
    • Assignment: EC-NUMBER
• Gene: Ec-16_001250
  • Source: annotation-esiliculosus_genome
    • Assignment: EC-NUMBER
• Gene: Ec-14_006530
  • Source: annotation-esiliculosus_genome
    • Assignment: AUTOMATED-NAME-MATCH
  • Source: orthology-aragem
• Gene: Ec-06_001380
  • Source: annotation-esiliculosus_genome
    • Assignment: EC-NUMBER
• Gene: Ec-17_000320
  • Source: orthology-aragem

Pathways

• PWY-5109, 2-methylbutanoate biosynthesis: PWY-5109
  • 4 reactions found over 6 reactions in the full pathway
• ILEUDEG-PWY, L-isoleucine degradation I: ILEUDEG-PWY
  • 6 reactions found over 6 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-aragem
    • Tool: pantograph
• Category: manual
  • Source: manual-erythro
  • Source: manual-sphingo361
  • Source: manual-sphingo391
  • Source: manual-hoflea
  • Source: manual-rhizobi
  • Source: manual-roseov420
  • Source: manual-imperaili
  • Source: manual-roseov134
  • Source: manual-marino
  • Source: manual-bosea
• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 31119
• LIGAND-RXN:
  • R04204