UBIQUITIN--PROTEIN-LIGASE-RXN

Reaction UBIQUITIN--PROTEIN-LIGASE-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • ubiquitin-protein transferase
  • Ubiquitin-activating enzyme e1, C-terminal
  • putative ubiquitin activating enzyme
  • Ubiquitin activating enzyme (E1) subunit UBA3
• ec number:
  • EC-6.2.1.45
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 ATP[c] + 1 Ubiquitin-C-Terminal-Glycine[c] + 1 Ubiquitin-activating-protein-E1-L-cys[c] => 1 AMP[c] + 1 PPI[c] + 1 S-ubiquitinyl-UAP-E1-L-cysteine[c]
• With common name(s):
  • 1 ATP[c] + 1 a [ubiquitin] C-terminal glycine[c] + 1 an [E1 ubiquitin-activating enzyme]-L-cysteine[c] => 1 AMP[c] + 1 diphosphate[c] + 1 an S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Ec-09_004750
  • Source: annotation-esiliculosus_genome
    • Assignment: EC-NUMBER
• Gene: Ec-26_001140
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-01_008900
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-25_002490
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-18_001830
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-01_001660
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-14_006720
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-16_001360
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-24_003940
  • Source: annotation-esiliculosus_genome
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: Ec-12_000320
  • Source: annotation-esiliculosus_genome
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: Ec-13_002660
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-01_007490
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-22_002200
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-01_009550
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-06_002450
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-25_000510
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-25_000920
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-14_003730
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-00_007160
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-25_000910
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-09_000720
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-14_001990
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-25_002630
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-27_002840
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-01_010570
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM

Pathways

• PWY-7511, protein ubiquitylation: PWY-7511
  • 9 reactions found over 9 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• LIGAND-RXN:
  • R03876
• UNIPROT:
  • P22314
  • P49459
  • P62256
  • P63146
  • P28263
  • Q02053
  • P62257
  • P61088
  • P63279
  • P19812
  • P21734
  • P25869
  • P31254
  • P15731
  • P15732
  • P29340
  • P35133
  • P35134
  • P35132
  • P33296
  • P22515
  • P39940
  • P42748
  • P42750
  • P42749
  • P42747
  • P50623
  • Q42973
  • P40984
  • Q92462
  • Q42540
  • P93028
  • P93393
  • P31252
  • P52486
  • Q9YGM6
  • O42646
  • O15979
  • P23566
  • Q96PU5
  • P27949