View source for 3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN

[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN 3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN] ==
* direction:
** REVERSIBLE
* common name:
** 3-methyl-2-oxobutanoate hydroxymethyltransferase
* ec number:
** [http://enzyme.expasy.org/EC/2.1.2.11 EC-2.1.2.11]
* Synonym(s):

== Reaction Formula ==
* With identifiers:
** 1 [[WATER]][c] '''+''' 1 [[2-KETO-ISOVALERATE]][c] '''+''' 1 [[METHYLENE-THF-GLU-N]][c] '''<=>''' 1 [[THF-GLU-N]][c] '''+''' 1 [[2-DEHYDROPANTOATE]][c]
* With common name(s):
** 1 H2O[c] '''+''' 1 3-methyl-2-oxobutanoate[c] '''+''' 1 a 5,10-methylene-tetrahydrofolate[c] '''<=>''' 1 a tetrahydrofolate[c] '''+''' 1 2-dehydropantoate[c]

== Genes associated with this reaction  ==
Genes have been associated with this reaction based on different elements listed below.
* Gene: [[Ec-01_001700]]
** Source: [[annotation-esiliculosus_genome]]
*** Assignment: GO-TERM
== Pathways  ==
* [[PANTO-PWY]], phosphopantothenate biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=PANTO-PWY PANTO-PWY]
** '''4''' reactions found over '''4''' reactions in the full pathway
== Reconstruction information  ==
* Category: [[annotation]]
** Source: [[annotation-esiliculosus_genome]]
*** Tool: [[pathwaytools]]
== External links  ==
* RHEA:
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=11824 11824]
* LIGAND-RXN:
** [http://www.genome.jp/dbget-bin/www_bget?R01226 R01226]
* UNIPROT:
** [http://www.uniprot.org/uniprot/Q9V0E1 Q9V0E1]
** [http://www.uniprot.org/uniprot/Q9JUY0 Q9JUY0]
** [http://www.uniprot.org/uniprot/P31057 P31057]
** [http://www.uniprot.org/uniprot/Q9PIK1 Q9PIK1]
** [http://www.uniprot.org/uniprot/P38122 P38122]
** [http://www.uniprot.org/uniprot/Q09672 Q09672]
** [http://www.uniprot.org/uniprot/P52997 P52997]
** [http://www.uniprot.org/uniprot/Q9X712 Q9X712]
** [http://www.uniprot.org/uniprot/Q9Y7B6 Q9Y7B6]
** [http://www.uniprot.org/uniprot/Q9L7B2 Q9L7B2]
** [http://www.uniprot.org/uniprot/Q9RKS2 Q9RKS2]
** [http://www.uniprot.org/uniprot/Q9RLE2 Q9RLE2]
{{#set: direction=REVERSIBLE}}
{{#set: common name=3-methyl-2-oxobutanoate hydroxymethyltransferase}}
{{#set: ec number=EC-2.1.2.11}}
{{#set: gene associated=Ec-01_001700}}
{{#set: in pathway=PANTO-PWY}}
{{#set: reconstruction category=annotation}}
{{#set: reconstruction source=annotation-esiliculosus_genome}}
{{#set: reconstruction tool=pathwaytools}}