View source for IMP-DEHYDROG-RXN

[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=IMP-DEHYDROG-RXN IMP-DEHYDROG-RXN] ==
* direction:
** REVERSIBLE
* common name:
** IMP dehydrogenase/GMP reductase
** IMP dehydrogenase
* ec number:
** [http://enzyme.expasy.org/EC/1.1.1.205 EC-1.1.1.205]
* Synonym(s):

== Reaction Formula ==
* With identifiers:
** 1 [[NAD]][c] '''+''' 1 [[IMP]][c] '''+''' 1 [[WATER]][c] '''<=>''' 1 [[XANTHOSINE-5-PHOSPHATE]][c] '''+''' 1 [[NADH]][c] '''+''' 1 [[PROTON]][c]
* With common name(s):
** 1 NAD+[c] '''+''' 1 IMP[c] '''+''' 1 H2O[c] '''<=>''' 1 XMP[c] '''+''' 1 NADH[c] '''+''' 1 H+[c]

== Genes associated with this reaction  ==
Genes have been associated with this reaction based on different elements listed below.
* Gene: [[Ec-24_002410]]
** Source: [[annotation-esiliculosus_genome]]
*** Assignment: GO-TERM
** Source: [[orthology-aragem]]
* Gene: [[Ec-19_000030]]
** Source: [[annotation-esiliculosus_genome]]
*** Assignment: AUTOMATED-NAME-MATCH
** Source: [[orthology-aragem]]
== Pathways  ==
* [[PWY-7221]], guanosine ribonucleotides de novo biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7221 PWY-7221]
** '''4''' reactions found over '''4''' reactions in the full pathway
* [[PWY-5695]], urate biosynthesis/inosine 5'-phosphate degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5695 PWY-5695]
** '''3''' reactions found over '''4''' reactions in the full pathway
* [[PWY-6596]], adenosine nucleotides degradation I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6596 PWY-6596]
** '''6''' reactions found over '''8''' reactions in the full pathway
== Reconstruction information  ==
* Category: [[orthology]]
** Source: [[orthology-aragem]]
*** Tool: [[pantograph]]
* Category: [[annotation]]
** Source: [[annotation-esiliculosus_genome]]
*** Tool: [[pathwaytools]]
== External links  ==
* RHEA:
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=11708 11708]
* LIGAND-RXN:
** [http://www.genome.jp/dbget-bin/www_bget?R01130 R01130]
* UNIPROT:
** [http://www.uniprot.org/uniprot/P12268 P12268]
** [http://www.uniprot.org/uniprot/P21620 P21620]
** [http://www.uniprot.org/uniprot/P50098 P50098]
** [http://www.uniprot.org/uniprot/P50097 P50097]
** [http://www.uniprot.org/uniprot/O26245 O26245]
** [http://www.uniprot.org/uniprot/Q9PAR5 Q9PAR5]
** [http://www.uniprot.org/uniprot/P65172 P65172]
** [http://www.uniprot.org/uniprot/Q9X168 Q9X168]
** [http://www.uniprot.org/uniprot/Q9KTW3 Q9KTW3]
** [http://www.uniprot.org/uniprot/Q9YBU2 Q9YBU2]
** [http://www.uniprot.org/uniprot/Q9CIY6 Q9CIY6]
** [http://www.uniprot.org/uniprot/P21879 P21879]
** [http://www.uniprot.org/uniprot/P0ADG7 P0ADG7]
** [http://www.uniprot.org/uniprot/P56088 P56088]
** [http://www.uniprot.org/uniprot/P49058 P49058]
** [http://www.uniprot.org/uniprot/O58045 O58045]
** [http://www.uniprot.org/uniprot/Q9UY49 Q9UY49]
** [http://www.uniprot.org/uniprot/Q9PKM2 Q9PKM2]
** [http://www.uniprot.org/uniprot/Q9RT87 Q9RT87]
** [http://www.uniprot.org/uniprot/Q9JUD0 Q9JUD0]
** [http://www.uniprot.org/uniprot/Q59011 Q59011]
** [http://www.uniprot.org/uniprot/Q9PNN3 Q9PNN3]
** [http://www.uniprot.org/uniprot/P44334 P44334]
** [http://www.uniprot.org/uniprot/O67820 O67820]
** [http://www.uniprot.org/uniprot/P65167 P65167]
** [http://www.uniprot.org/uniprot/Q9ZL14 Q9ZL14]
** [http://www.uniprot.org/uniprot/Q9JZB5 Q9JZB5]
** [http://www.uniprot.org/uniprot/Q9HXM5 Q9HXM5]
** [http://www.uniprot.org/uniprot/P0C0H6 P0C0H6]
** [http://www.uniprot.org/uniprot/P42851 P42851]
** [http://www.uniprot.org/uniprot/P47996 P47996]
** [http://www.uniprot.org/uniprot/Q9RHG9 Q9RHG9]
** [http://www.uniprot.org/uniprot/P24547 P24547]
** [http://www.uniprot.org/uniprot/Q9RHG1 Q9RHG1]
** [http://www.uniprot.org/uniprot/P31002 P31002]
** [http://www.uniprot.org/uniprot/Q07152 Q07152]
** [http://www.uniprot.org/uniprot/P38697 P38697]
** [http://www.uniprot.org/uniprot/P50094 P50094]
** [http://www.uniprot.org/uniprot/P39567 P39567]
** [http://www.uniprot.org/uniprot/P50095 P50095]
** [http://www.uniprot.org/uniprot/Q49729 Q49729]
** [http://www.uniprot.org/uniprot/O14344 O14344]
** [http://www.uniprot.org/uniprot/O32912 O32912]
{{#set: direction=REVERSIBLE}}
{{#set: common name=IMP dehydrogenase/GMP reductase}}
{{#set: common name=IMP dehydrogenase}}
{{#set: ec number=EC-1.1.1.205}}
{{#set: gene associated=Ec-24_002410|Ec-19_000030}}
{{#set: in pathway=PWY-7221|PWY-5695|PWY-6596}}
{{#set: reconstruction category=orthology|annotation}}
{{#set: reconstruction source=annotation-esiliculosus_genome|orthology-aragem}}
{{#set: reconstruction tool=pantograph|pathwaytools}}