Difference between revisions of "GMP-REDUCT-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=SUC SUC] == * smiles: ** C(C([O-])=O)CC([O-])=O * inchi key: ** InChIKey=KDYFGRWQOYBRFD-UHFFFAO...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=GMP-REDUCT-RXN GMP-REDUCT-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** IMP dehydrogenase...")
 
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[[Category:Metabolite]]
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[[Category:Reaction]]
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=SUC SUC] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=GMP-REDUCT-RXN GMP-REDUCT-RXN] ==
* smiles:
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* direction:
** C(C([O-])=O)CC([O-])=O
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** LEFT-TO-RIGHT
* inchi key:
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** InChIKey=KDYFGRWQOYBRFD-UHFFFAOYSA-L
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* common name:
 
* common name:
** succinate
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** IMP dehydrogenase/GMP reductase
* molecular weight:
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* ec number:
** 116.073   
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** [http://enzyme.expasy.org/EC/1.7.1.7 EC-1.7.1.7]
 
* Synonym(s):
 
* Synonym(s):
** succinic acid
 
** suc
 
** succ
 
** butanedioic acid
 
** ethylenesuccinic acid
 
  
== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
* [[RXN-15378]]
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* With identifiers:
* [[biomass_rxn]]
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** 1 [[NADPH]][c] '''+''' 2 [[PROTON]][c] '''+''' 1 [[GMP]][c] '''=>''' 1 [[AMMONIUM]][c] '''+''' 1 [[IMP]][c] '''+''' 1 [[NADP]][c]
* [[RXN-14971]]
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* With common name(s):
* [[SUCCINATE-DEHYDROGENASE-UBIQUINONE-RXN]]
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** 1 NADPH[c] '''+''' 2 H+[c] '''+''' 1 GMP[c] '''=>''' 1 ammonium[c] '''+''' 1 IMP[c] '''+''' 1 NADP+[c]
== Reaction(s) known to produce the compound ==
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* [[RXN-7775]]
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== Genes associated with this reaction  ==
* [[RXN-7648]]
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Genes have been associated with this reaction based on different elements listed below.
* [[RXN-527]]
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* Gene: [[Ec-19_000030]]
* [[RXN-113]]
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** Source: [[annotation-esiliculosus_genome]]
* [[RXN490-3641]]
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*** Assignment: AUTOMATED-NAME-MATCH
* [[RXN-115]]
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== Pathways  ==
* [[O-SUCCHOMOSERLYASE-RXN]]
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== Reconstruction information  ==
* [[RXN-171]]
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* Category: [[annotation]]
* [[RXN-8450]]
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** Source: [[annotation-esiliculosus_genome]]
* [[NARINGENIN-3-DIOXYGENASE-RXN]]
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*** Tool: [[pathwaytools]]
* [[1.14.11.2-RXN]]
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* [[RXN66-470]]
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* [[RXN-7922]]
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* [[RXN-6550]]
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* [[RXN-602]]
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* [[METBALT-RXN]]
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* [[PEPTIDE-ASPARTATE-BETA-DIOXYGENASE-RXN]]
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* [[RXN1F-93]]
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* [[RXN1F-168]]
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* [[RXN0-5245]]
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* [[RXN1F-165]]
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* [[1.14.11.18-RXN]]
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* [[RXN1F-167]]
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* [[RXN1F-162]]
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* [[RXN1F-163]]
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== Reaction(s) of unknown directionality ==
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* [[FUMARATE-REDUCTASE-NADH-RXN]]
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* [[SUCCINATE--COA-LIGASE-GDP-FORMING-RXN]]
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* [[RXN-9384]]
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* [[ISOCIT-CLEAV-RXN]]
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* [[SUCCCOASYN-RXN]]
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* [[RXN-1744]]
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== External links  ==
 
== External links  ==
* CAS : 110-15-6
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* RHEA:
* BIGG : 33633
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=17185 17185]
* PUBCHEM:
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* LIGAND-RXN:
** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=160419 160419]
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** [http://www.genome.jp/dbget-bin/www_bget?R01134 R01134]
* KNAPSACK : C00001205
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* UNIPROT:
* HMDB : HMDB00254
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** [http://www.uniprot.org/uniprot/Q9ZKZ2 Q9ZKZ2]
* LIGAND-CPD:
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** [http://www.uniprot.org/uniprot/Q9CGF1 Q9CGF1]
** [http://www.genome.jp/dbget-bin/www_bget?C00042 C00042]
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** [http://www.uniprot.org/uniprot/P36959 P36959]
* CHEMSPIDER:
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** [http://www.uniprot.org/uniprot/O05269 O05269]
** [http://www.chemspider.com/Chemical-Structure.140973.html 140973]
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** [http://www.uniprot.org/uniprot/O25525 O25525]
* CHEBI:
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** [http://www.uniprot.org/uniprot/P60560 P60560]
** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=30031 30031]
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** [http://www.uniprot.org/uniprot/O16294 O16294]
* METABOLIGHTS : MTBLC30031
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{{#set: direction=LEFT-TO-RIGHT}}
{{#set: smiles=C(C([O-])=O)CC([O-])=O}}
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{{#set: common name=IMP dehydrogenase/GMP reductase}}
{{#set: inchi key=InChIKey=KDYFGRWQOYBRFD-UHFFFAOYSA-L}}
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{{#set: ec number=EC-1.7.1.7}}
{{#set: common name=succinate}}
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{{#set: gene associated=Ec-19_000030}}
{{#set: molecular weight=116.073    }}
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{{#set: in pathway=}}
{{#set: common name=succinic acid|suc|succ|butanedioic acid|ethylenesuccinic acid}}
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{{#set: reconstruction category=annotation}}
{{#set: consumed by=RXN-15378|biomass_rxn|RXN-14971|SUCCINATE-DEHYDROGENASE-UBIQUINONE-RXN}}
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{{#set: reconstruction source=annotation-esiliculosus_genome}}
{{#set: produced by=RXN-7775|RXN-7648|RXN-527|RXN-113|RXN490-3641|RXN-115|O-SUCCHOMOSERLYASE-RXN|RXN-171|RXN-8450|NARINGENIN-3-DIOXYGENASE-RXN|1.14.11.2-RXN|RXN66-470|RXN-7922|RXN-6550|RXN-602|METBALT-RXN|PEPTIDE-ASPARTATE-BETA-DIOXYGENASE-RXN|RXN1F-93|RXN1F-168|RXN0-5245|RXN1F-165|1.14.11.18-RXN|RXN1F-167|RXN1F-162|RXN1F-163}}
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{{#set: reconstruction tool=pathwaytools}}
{{#set: reversible reaction associated=FUMARATE-REDUCTASE-NADH-RXN|SUCCINATE--COA-LIGASE-GDP-FORMING-RXN|RXN-9384|ISOCIT-CLEAV-RXN|SUCCCOASYN-RXN|RXN-1744}}
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Latest revision as of 20:07, 21 March 2018

Reaction GMP-REDUCT-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • IMP dehydrogenase/GMP reductase
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 NADPH[c] + 2 H+[c] + 1 GMP[c] => 1 ammonium[c] + 1 IMP[c] + 1 NADP+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

Reconstruction information

External links