Difference between revisions of "H2PTERIDINEPYROPHOSPHOKIN-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=AMMONIUM AMMONIUM] == * smiles: ** [NH4+] * inchi key: ** InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-O...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=H2PTERIDINEPYROPHOSPHOKIN-RXN H2PTERIDINEPYROPHOSPHOKIN-RXN] == * direction: ** LEFT-TO-RIGHT * com...")
 
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[[Category:Metabolite]]
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[[Category:Reaction]]
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=AMMONIUM AMMONIUM] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=H2PTERIDINEPYROPHOSPHOKIN-RXN H2PTERIDINEPYROPHOSPHOKIN-RXN] ==
* smiles:
+
* direction:
** [NH4+]
+
** LEFT-TO-RIGHT
* inchi key:
+
** InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-O
+
 
* common name:
 
* common name:
** ammonium
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** 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
* molecular weight:
+
* ec number:
** 18.038   
+
** [http://enzyme.expasy.org/EC/2.7.6.3 EC-2.7.6.3]
 
* Synonym(s):
 
* Synonym(s):
** NH4+
 
  
== Reaction(s) known to consume the compound ==
+
== Reaction Formula ==
* [[GLUTAMINESYN-RXN]]
+
* With identifiers:
* [[ASNSYNA-RXN]]
+
** 1 [[ATP]][c] '''+''' 1 [[AMINO-OH-HYDROXYMETHYL-DIHYDROPTERIDINE]][c] '''=>''' 1 [[AMP]][c] '''+''' 1 [[DIHYDROPTERIN-CH2OH-PP]][c] '''+''' 1 [[PROTON]][c]
* [[RXN-13202]]
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* With common name(s):
* [[GMP-SYN-NH3-RXN]]
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** 1 ATP[c] '''+''' 1 6-(hydroxymethyl)-7,8-dihydropterin[c] '''=>''' 1 AMP[c] '''+''' 1 (7,8-dihydropterin-6-yl)methyl diphosphate[c] '''+''' 1 H+[c]
* [[RXN-9615]]
+
 
* [[RXN-16910]]
+
== Genes associated with this reaction  ==
* [[RXN-14325]]
+
Genes have been associated with this reaction based on different elements listed below.
* [[NAD-SYNTH-NH3-RXN]]
+
* Gene: [[Ec-12_000230]]
== Reaction(s) known to produce the compound ==
+
** Source: [[annotation-esiliculosus_genome]]
* [[HOMOSERDEAM-RXN]]
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*** Assignment: GO-TERM
* [[BETA-UREIDOPROPIONASE-RXN]]
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** Source: [[orthology-aragem]]
* [[RXN0-5222]]
+
== Pathways  ==
* [[GMP-REDUCT-RXN]]
+
* [[PWY-7539]], 6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7539 PWY-7539]
* [[DCMP-DEAMINASE-RXN]]
+
** '''4''' reactions found over '''5''' reactions in the full pathway
* [[RXN-6381]]
+
* [[PWY-6797]], 6-hydroxymethyl-dihydropterin diphosphate biosynthesis II (archaea): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6797 PWY-6797]
* [[RXNN-404]]
+
** '''3''' reactions found over '''7''' reactions in the full pathway
* [[AGMATINE-DEIMINASE-RXN]]
+
* [[PWY-6147]], 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6147 PWY-6147]
* [[GLUTAMIN-RXN]]
+
** '''5''' reactions found over '''5''' reactions in the full pathway
* [[ADENODEAMIN-RXN]]
+
== Reconstruction information  ==
* [[AMP-DEAMINASE-RXN]]
+
* Category: [[orthology]]
* [[PYRAZIN-RXN]]
+
** Source: [[orthology-aragem]]
* [[PROTEIN-ARGININE-DEIMINASE-RXN]]
+
*** Tool: [[pantograph]]
* [[RXN-11784]]
+
* Category: [[annotation]]
* [[R311-RXN]]
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** Source: [[annotation-esiliculosus_genome]]
* [[LCYSDESULF-RXN]]
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*** Tool: [[pathwaytools]]
* [[AMACETOXID-RXN]]
+
* [[CYSTHIOCYS-RXN]]
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* [[N-CARBAMOYLPUTRESCINE-AMIDASE-RXN]]
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* [[RXN-11210]]
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* [[RXN-9615]]
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* [[PMPOXI-RXN]]
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* [[FERREDOXIN--NITRITE-REDUCTASE-RXN]]
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* [[CYTIDEAM2-RXN]]
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* [[RIBOFLAVINSYNDEAM-RXN]]
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* [[AMINEOXID-RXN]]
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* [[RXN-646]]
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* [[CYSTATHIONINE-BETA-LYASE-RXN]]
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* [[4.1.99.4-RXN]]
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* [[ORNITHINE-CYCLODEAMINASE-RXN]]
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* [[ASPARAGHYD-RXN]]
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* [[THREDEHYD-RXN]]
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* [[RXN-1404]]
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* [[RXN6666-4]]
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* [[RXN-9597]]
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* [[METBALT-RXN]]
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* [[AMINEPHEN-RXN]]
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* [[RXN-5821]]
+
* [[RXN-15127]]
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* [[RXN-15130]]
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* [[HISTIDINE-AMMONIA-LYASE-RXN]]
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* [[RXN-15123]]
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* [[RXN-8899]]
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* [[RXN-12729]]
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* [[OHMETHYLBILANESYN-RXN]]
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* [[GUANIDINOBUTANAMIDE-NH3-RXN]]
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* [[ADDALT-RXN]]
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== Reaction(s) of unknown directionality ==
+
* [[RXN-14727]]
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* [[ALANINE-DEHYDROGENASE-RXN]]
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* [[GCVMULTI-RXN]]
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* [[GCVMULTI-RXN-GLY/THF/NAD//METHYLENE-THF/AMMONIUM/CARBON-DIOXIDE/NADH.56.]]
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* [[RXN-17608]]
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* [[GLUTAMATE-DEHYDROGENASE-RXN]]
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* [[L-AMINO-ACID-DEHYDROGENASE-RXN-TYR/NAD/WATER//P-HYDROXY-PHENYLPYRUVATE/AMMONIUM/NADH/PROTON.61.]]
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* [[RXN-12878]]
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* [[RXN-14728]]
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* [[AMIDASE-RXN]]
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* [[GCVT-RXN]]
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* [[GLUTDEHYD-RXN]]
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* [[RXN-11811]]
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* [[CARBAMATE-KINASE-RXN]]
+
 
== External links  ==
 
== External links  ==
* CAS : 14798-03-9
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* RHEA:
* BIGG : 33515
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=11412 11412]
* PUBCHEM:
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* LIGAND-RXN:
** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=223 223]
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** [http://www.genome.jp/dbget-bin/www_bget?R03503 R03503]
* HMDB : HMDB41827
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* UNIPROT:
* LIGAND-CPD:
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** [http://www.uniprot.org/uniprot/P22291 P22291]
** [http://www.genome.jp/dbget-bin/www_bget?C01342 C01342]
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** [http://www.uniprot.org/uniprot/P26281 P26281]
* CHEMSPIDER:
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** [http://www.uniprot.org/uniprot/O84619 O84619]
** [http://www.chemspider.com/Chemical-Structure.218.html 218]
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** [http://www.uniprot.org/uniprot/Q9ZM35 Q9ZM35]
* CHEBI:
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** [http://www.uniprot.org/uniprot/Q9RXY4 Q9RXY4]
** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=28938 28938]
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** [http://www.uniprot.org/uniprot/O66550 O66550]
* METABOLIGHTS : MTBLC28938
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** [http://www.uniprot.org/uniprot/O25680 O25680]
{{#set: smiles=[NH4+]}}
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** [http://www.uniprot.org/uniprot/Q9PJ54 Q9PJ54]
{{#set: inchi key=InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-O}}
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** [http://www.uniprot.org/uniprot/Q9JV81 Q9JV81]
{{#set: common name=ammonium}}
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** [http://www.uniprot.org/uniprot/P64143 P64143]
{{#set: molecular weight=18.038    }}
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** [http://www.uniprot.org/uniprot/Q9Z7E8 Q9Z7E8]
{{#set: common name=NH4+}}
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** [http://www.uniprot.org/uniprot/P82602 P82602]
{{#set: consumed by=GLUTAMINESYN-RXN|ASNSYNA-RXN|RXN-13202|GMP-SYN-NH3-RXN|RXN-9615|RXN-16910|RXN-14325|NAD-SYNTH-NH3-RXN}}
+
** [http://www.uniprot.org/uniprot/P29252 P29252]
{{#set: produced by=HOMOSERDEAM-RXN|BETA-UREIDOPROPIONASE-RXN|RXN0-5222|GMP-REDUCT-RXN|DCMP-DEAMINASE-RXN|RXN-6381|RXNN-404|AGMATINE-DEIMINASE-RXN|GLUTAMIN-RXN|ADENODEAMIN-RXN|AMP-DEAMINASE-RXN|PYRAZIN-RXN|PROTEIN-ARGININE-DEIMINASE-RXN|RXN-11784|R311-RXN|LCYSDESULF-RXN|AMACETOXID-RXN|CYSTHIOCYS-RXN|N-CARBAMOYLPUTRESCINE-AMIDASE-RXN|RXN-11210|RXN-9615|PMPOXI-RXN|FERREDOXIN--NITRITE-REDUCTASE-RXN|CYTIDEAM2-RXN|RIBOFLAVINSYNDEAM-RXN|AMINEOXID-RXN|RXN-646|CYSTATHIONINE-BETA-LYASE-RXN|4.1.99.4-RXN|ORNITHINE-CYCLODEAMINASE-RXN|ASPARAGHYD-RXN|THREDEHYD-RXN|RXN-1404|RXN6666-4|RXN-9597|METBALT-RXN|AMINEPHEN-RXN|RXN-5821|RXN-15127|RXN-15130|HISTIDINE-AMMONIA-LYASE-RXN|RXN-15123|RXN-8899|RXN-12729|OHMETHYLBILANESYN-RXN|GUANIDINOBUTANAMIDE-NH3-RXN|ADDALT-RXN}}
+
** [http://www.uniprot.org/uniprot/P72736 P72736]
{{#set: reversible reaction associated=RXN-14727|ALANINE-DEHYDROGENASE-RXN|GCVMULTI-RXN|GCVMULTI-RXN-GLY/THF/NAD//METHYLENE-THF/AMMONIUM/CARBON-DIOXIDE/NADH.56.|RXN-17608|GLUTAMATE-DEHYDROGENASE-RXN|L-AMINO-ACID-DEHYDROGENASE-RXN-TYR/NAD/WATER//P-HYDROXY-PHENYLPYRUVATE/AMMONIUM/NADH/PROTON.61.|RXN-12878|RXN-14728|AMIDASE-RXN|GCVT-RXN|GLUTDEHYD-RXN|RXN-11811|CARBAMATE-KINASE-RXN}}
+
** [http://www.uniprot.org/uniprot/O04862 O04862]
 +
** [http://www.uniprot.org/uniprot/Q9SZV3 Q9SZV3]
 +
** [http://www.uniprot.org/uniprot/Q9X8I1 Q9X8I1]
 +
{{#set: direction=LEFT-TO-RIGHT}}
 +
{{#set: common name=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase}}
 +
{{#set: ec number=EC-2.7.6.3}}
 +
{{#set: gene associated=Ec-12_000230}}
 +
{{#set: in pathway=PWY-7539|PWY-6797|PWY-6147}}
 +
{{#set: reconstruction category=orthology|annotation}}
 +
{{#set: reconstruction source=annotation-esiliculosus_genome|orthology-aragem}}
 +
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 20:19, 21 March 2018

Reaction H2PTERIDINEPYROPHOSPHOKIN-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-7539, 6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia): PWY-7539
    • 4 reactions found over 5 reactions in the full pathway
  • PWY-6797, 6-hydroxymethyl-dihydropterin diphosphate biosynthesis II (archaea): PWY-6797
    • 3 reactions found over 7 reactions in the full pathway
  • PWY-6147, 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I: PWY-6147
    • 5 reactions found over 5 reactions in the full pathway

Reconstruction information

External links