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− | [[Category:Reaction]] | + | [[Category:Metabolite]] |
− | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=SUCCCOASYN-RXN SUCCCOASYN-RXN] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=ACETYL-ACP ACETYL-ACP] == |
− | * direction:
| + | |
− | ** REVERSIBLE
| + | |
| * common name: | | * common name: |
− | ** Succinate:CoA ligase (ADP-forming) | + | ** an acetyl-[acp] |
− | * ec number:
| + | |
− | ** [http://enzyme.expasy.org/EC/6.2.1.5 EC-6.2.1.5]
| + | |
| * Synonym(s): | | * Synonym(s): |
− | ** Succinate thiokinase | + | ** acetyl-[acyl-carrier protein] |
− | ** succinyl CoA synthesis | + | ** acetylacylcarrier-protein |
| | | |
− | == Reaction Formula == | + | == Reaction(s) known to consume the compound == |
− | * With identifiers:
| + | * [[3-OXOACYL-ACP-SYNTH-BASE-RXN]] |
− | ** 1 [[CO-A]][c] '''+''' 1 [[SUC]][c] '''+''' 1 [[ATP]][c] '''<=>''' 1 [[SUC-COA]][c] '''+''' 1 [[Pi]][c] '''+''' 1 [[ADP]][c]
| + | == Reaction(s) known to produce the compound == |
− | * With common name(s):
| + | == Reaction(s) of unknown directionality == |
− | ** 1 coenzyme A[c] '''+''' 1 succinate[c] '''+''' 1 ATP[c] '''<=>''' 1 succinyl-CoA[c] '''+''' 1 phosphate[c] '''+''' 1 ADP[c]
| + | * [[ACP-S-ACETYLTRANSFER-RXN]] |
− | | + | |
− | == Genes associated with this reaction == | + | |
− | Genes have been associated with this reaction based on different elements listed below.
| + | |
− | * Gene: [[Ec-10_000030]] | + | |
− | ** Source: [[orthology-aragem]]
| + | |
− | * Gene: [[Ec-02_001020]]
| + | |
− | ** Source: [[annotation-esiliculosus_genome]]
| + | |
− | *** Assignment: EC-NUMBER
| + | |
− | ** Source: [[orthology-aragem]]
| + | |
− | == Pathways == | + | |
− | * [[PWY-5913]], partial TCA cycle (obligate autotrophs): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5913 PWY-5913]
| + | |
− | ** '''10''' reactions found over '''11''' reactions in the full pathway
| + | |
− | * [[P42-PWY]], incomplete reductive TCA cycle: [http://metacyc.org/META/NEW-IMAGE?object=P42-PWY P42-PWY]
| + | |
− | ** '''5''' reactions found over '''7''' reactions in the full pathway
| + | |
− | * [[PWY-5537]], pyruvate fermentation to acetate V: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5537 PWY-5537]
| + | |
− | ** '''2''' reactions found over '''4''' reactions in the full pathway
| + | |
− | * [[PWY-7384]], anaerobic energy metabolism (invertebrates, mitochondrial): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7384 PWY-7384]
| + | |
− | ** '''6''' reactions found over '''12''' reactions in the full pathway
| + | |
− | * [[PWY-5392]], reductive TCA cycle II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5392 PWY-5392]
| + | |
− | ** '''6''' reactions found over '''12''' reactions in the full pathway
| + | |
− | * [[P23-PWY]], reductive TCA cycle I: [http://metacyc.org/META/NEW-IMAGE?object=P23-PWY P23-PWY]
| + | |
− | ** '''10''' reactions found over '''12''' reactions in the full pathway
| + | |
− | * [[PWY-6969]], TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6969 PWY-6969]
| + | |
− | ** '''10''' reactions found over '''12''' reactions in the full pathway
| + | |
− | * [[PWY-6728]], methylaspartate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6728 PWY-6728]
| + | |
− | ** '''11''' reactions found over '''18''' reactions in the full pathway
| + | |
− | * [[PWY-5538]], pyruvate fermentation to acetate VI: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5538 PWY-5538]
| + | |
− | ** '''2''' reactions found over '''4''' reactions in the full pathway
| + | |
− | * [[PWY-5690]], TCA cycle II (plants and fungi): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5690 PWY-5690]
| + | |
− | ** '''8''' reactions found over '''9''' reactions in the full pathway
| + | |
− | * [[PWY66-398]], TCA cycle III (animals): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-398 PWY66-398]
| + | |
− | ** '''10''' reactions found over '''11''' reactions in the full pathway
| + | |
− | * [[TCA]], TCA cycle I (prokaryotic): [http://metacyc.org/META/NEW-IMAGE?object=TCA TCA] | + | |
− | ** '''9''' reactions found over '''10''' reactions in the full pathway
| + | |
− | == Reconstruction information ==
| + | |
− | * Category: [[orthology]]
| + | |
− | ** Source: [[orthology-aragem]]
| + | |
− | *** Tool: [[pantograph]]
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− | * Category: [[annotation]]
| + | |
− | ** Source: [[annotation-esiliculosus_genome]]
| + | |
− | *** Tool: [[pathwaytools]]
| + | |
| == External links == | | == External links == |
− | * RHEA:
| + | {{#set: common name=an acetyl-[acp]}} |
− | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=17661 17661]
| + | {{#set: common name=acetyl-[acyl-carrier protein]|acetylacylcarrier-protein}} |
− | * LIGAND-RXN:
| + | {{#set: consumed by=3-OXOACYL-ACP-SYNTH-BASE-RXN}} |
− | ** [http://www.genome.jp/dbget-bin/www_bget?R00405 R00405]
| + | {{#set: reversible reaction associated=ACP-S-ACETYLTRANSFER-RXN}} |
− | * UNIPROT:
| + | |
− | ** [http://www.uniprot.org/uniprot/O28098 O28098]
| + | |
− | ** [http://www.uniprot.org/uniprot/P53594 P53594]
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− | ** [http://www.uniprot.org/uniprot/O28733 O28733]
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− | ** [http://www.uniprot.org/uniprot/P45101 P45101]
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− | ** [http://www.uniprot.org/uniprot/P45102 P45102]
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− | ** [http://www.uniprot.org/uniprot/Q9JUT0 Q9JUT0]
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− | ** [http://www.uniprot.org/uniprot/Q58643 Q58643]
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− | ** [http://www.uniprot.org/uniprot/O26663 O26663]
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− | ** [http://www.uniprot.org/uniprot/P80886 P80886]
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− | ** [http://www.uniprot.org/uniprot/Q9PHY1 Q9PHY1]
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− | ** [http://www.uniprot.org/uniprot/Q9JUS9 Q9JUS9]
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− | ** [http://www.uniprot.org/uniprot/P80865 P80865]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9PHY0 Q9PHY0]
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− | ** [http://www.uniprot.org/uniprot/O67729 O67729]
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− | ** [http://www.uniprot.org/uniprot/O67546 O67546]
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− | ** [http://www.uniprot.org/uniprot/P53593 P53593]
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− | ** [http://www.uniprot.org/uniprot/P0AGE9 P0AGE9]
| + | |
− | ** [http://www.uniprot.org/uniprot/P0A836 P0A836]
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− | ** [http://www.uniprot.org/uniprot/O82662 O82662]
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− | {{#set: direction=REVERSIBLE}}
| + | |
− | {{#set: common name=Succinate:CoA ligase (ADP-forming)}} | + | |
− | {{#set: ec number=EC-6.2.1.5}}
| + | |
− | {{#set: common name=Succinate thiokinase|succinyl CoA synthesis}} | + | |
− | {{#set: gene associated=Ec-10_000030|Ec-02_001020}}
| + | |
− | {{#set: in pathway=PWY-5913|P42-PWY|PWY-5537|PWY-7384|PWY-5392|P23-PWY|PWY-6969|PWY-6728|PWY-5538|PWY-5690|PWY66-398|TCA}} | + | |
− | {{#set: reconstruction category=orthology|annotation}} | + | |
− | {{#set: reconstruction source=annotation-esiliculosus_genome|orthology-aragem}}
| + | |
− | {{#set: reconstruction tool=pantograph|pathwaytools}}
| + | |