Difference between revisions of "THYMIDYLATESYN-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=PHEAMINOTRANS-RXN PHEAMINOTRANS-RXN] == * direction: ** REVERSIBLE * ec number: ** [http://enzyme.e...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=THYMIDYLATESYN-RXN THYMIDYLATESYN-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** thymidyla...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=PHEAMINOTRANS-RXN PHEAMINOTRANS-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=THYMIDYLATESYN-RXN THYMIDYLATESYN-RXN] ==
 
* direction:
 
* direction:
−
** REVERSIBLE
+
** LEFT-TO-RIGHT
 +
* common name:
 +
** thymidylate synthase
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/2.6.1.57 EC-2.6.1.57]
+
** [http://enzyme.expasy.org/EC/2.1.1.45 EC-2.1.1.45]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[GLT]][c] '''+''' 1 [[PHENYL-PYRUVATE]][c] '''<=>''' 1 [[PHE]][c] '''+''' 1 [[2-KETOGLUTARATE]][c]
+
** 1 [[METHYLENE-THF-GLU-N]][c] '''+''' 1 [[DUMP]][c] '''=>''' 1 [[DIHYDROFOLATE-GLU-N]][c] '''+''' 1 [[TMP]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 L-glutamate[c] '''+''' 1 2-oxo-3-phenylpropanoate[c] '''<=>''' 1 L-phenylalanine[c] '''+''' 1 2-oxoglutarate[c]
+
** 1 a 5,10-methylene-tetrahydrofolate[c] '''+''' 1 dUMP[c] '''=>''' 1 a 7,8-dihydrofolate[c] '''+''' 1 dTMP[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* [[Ec-03_003270]]
+
* Gene: [[Ec-27_004630]]
−
** [[pantograph]]-[[aragem]]
+
** Source: [[annotation-esiliculosus_genome]]
−
* [[Ec-12_000850]]
+
*** Assignment: GO-TERM
−
** [[pantograph]]-[[aragem]]
+
−
* [[Ec-09_004540]]
+
−
** [[pantograph]]-[[aragem]]
+
−
* [[Ec-23_003500]]
+
−
** [[pantograph]]-[[aragem]]
+
−
* [[Ec-01_007480]]
+
−
** [[pantograph]]-[[aragem]]
+
−
* [[Ec-00_001230]]
+
−
** [[pantograph]]-[[aragem]]
+
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-5079]], L-phenylalanine degradation III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5079 PWY-5079]
+
* [[PWY-7210]], pyrimidine deoxyribonucleotides biosynthesis from CTP: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7210 PWY-7210]
−
** '''1''' reactions found over '''4''' reactions in the full pathway
+
** '''8''' reactions found over '''8''' reactions in the full pathway
−
* [[PWY-7432]], L-phenylalanine biosynthesis III (cytosolic, plants): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7432 PWY-7432]
+
* [[PWY-7198]], pyrimidine deoxyribonucleotides de novo biosynthesis IV: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7198 PWY-7198]
−
** '''4''' reactions found over '''4''' reactions in the full pathway
+
** '''6''' reactions found over '''7''' reactions in the full pathway
−
* [[ANAPHENOXI-PWY]], L-phenylalanine degradation II (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=ANAPHENOXI-PWY ANAPHENOXI-PWY]
+
* [[PWY-7199]], pyrimidine deoxyribonucleosides salvage: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7199 PWY-7199]
−
** '''2''' reactions found over '''3''' reactions in the full pathway
+
** '''1''' reactions found over '''5''' reactions in the full pathway
−
* [[PHESYN]], L-phenylalanine biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=PHESYN PHESYN]
+
* [[PWY-3841]], folate transformations II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-3841 PWY-3841]
−
** '''3''' reactions found over '''3''' reactions in the full pathway
+
** '''10''' reactions found over '''11''' reactions in the full pathway
 +
* [[1CMET2-PWY]], N10-formyl-tetrahydrofolate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=1CMET2-PWY 1CMET2-PWY]
 +
** '''9''' reactions found over '''9''' reactions in the full pathway
 +
* [[PWY-7187]], pyrimidine deoxyribonucleotides de novo biosynthesis II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7187 PWY-7187]
 +
** '''6''' reactions found over '''7''' reactions in the full pathway
 +
* [[PWY0-166]], superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli): [http://metacyc.org/META/NEW-IMAGE?object=PWY0-166 PWY0-166]
 +
** '''14''' reactions found over '''17''' reactions in the full pathway
 +
* [[PWY-7184]], pyrimidine deoxyribonucleotides de novo biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7184 PWY-7184]
 +
** '''9''' reactions found over '''9''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
−
* Category: [[orthology]]
+
* Category: [[annotation]]
−
** Source: [[orthology-aragem]]
+
** Source: [[annotation-esiliculosus_genome]]
−
*** Tool: [[pantograph]]
+
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=25152 25152]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=12104 12104]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R00694 R00694]
+
** [http://www.genome.jp/dbget-bin/www_bget?R02101 R02101]
 
* UNIPROT:
 
* UNIPROT:
−
** [http://www.uniprot.org/uniprot/O84642 O84642]
+
** [http://www.uniprot.org/uniprot/P19368 P19368]
−
** [http://www.uniprot.org/uniprot/Q02636 Q02636]
+
** [http://www.uniprot.org/uniprot/Q07422 Q07422]
−
** [http://www.uniprot.org/uniprot/Q9Z7G5 Q9Z7G5]
+
** [http://www.uniprot.org/uniprot/P47469 P47469]
−
** [http://www.uniprot.org/uniprot/Q9V0L2 Q9V0L2]
+
** [http://www.uniprot.org/uniprot/Q9JT57 Q9JT57]
−
** [http://www.uniprot.org/uniprot/Q9PHA8 Q9PHA8]
+
** [http://www.uniprot.org/uniprot/P42326 P42326]
−
** [http://www.uniprot.org/uniprot/O59096 O59096]
+
** [http://www.uniprot.org/uniprot/O02604 O02604]
−
** [http://www.uniprot.org/uniprot/O58489 O58489]
+
** [http://www.uniprot.org/uniprot/P07382 P07382]
−
** [http://www.uniprot.org/uniprot/Q9UZ63 Q9UZ63]
+
** [http://www.uniprot.org/uniprot/P16126 P16126]
−
** [http://www.uniprot.org/uniprot/Q9JT83 Q9JT83]
+
** [http://www.uniprot.org/uniprot/P13922 P13922]
−
** [http://www.uniprot.org/uniprot/Q9JYA1 Q9JYA1]
+
** [http://www.uniprot.org/uniprot/P20712 P20712]
−
** [http://www.uniprot.org/uniprot/P95468 P95468]
+
** [http://www.uniprot.org/uniprot/P11044 P11044]
−
** [http://www.uniprot.org/uniprot/Q9UWK9 Q9UWK9]
+
** [http://www.uniprot.org/uniprot/P45350 P45350]
−
** [http://www.uniprot.org/uniprot/Q9UWK8 Q9UWK8]
+
** [http://www.uniprot.org/uniprot/P45352 P45352]
−
** [http://www.uniprot.org/uniprot/P74861 P74861]
+
** [http://www.uniprot.org/uniprot/P51820 P51820]
−
** [http://www.uniprot.org/uniprot/P04693 P04693]
+
** [http://www.uniprot.org/uniprot/P0C0M4 P0C0M4]
−
{{#set: direction=REVERSIBLE}}
+
** [http://www.uniprot.org/uniprot/Q27828 Q27828]
−
{{#set: ec number=EC-2.6.1.57}}
+
** [http://www.uniprot.org/uniprot/P09249 P09249]
−
{{#set: gene associated=Ec-03_003270|Ec-12_000850|Ec-09_004540|Ec-23_003500|Ec-01_007480|Ec-00_001230}}
+
** [http://www.uniprot.org/uniprot/P12462 P12462]
−
{{#set: in pathway=PWY-5079|PWY-7432|ANAPHENOXI-PWY|PHESYN}}
+
** [http://www.uniprot.org/uniprot/P07606 P07606]
−
{{#set: reconstruction category=orthology}}
+
** [http://www.uniprot.org/uniprot/P00471 P00471]
−
{{#set: reconstruction source=orthology-aragem}}
+
** [http://www.uniprot.org/uniprot/P0A884 P0A884]
−
{{#set: reconstruction tool=pantograph}}
+
** [http://www.uniprot.org/uniprot/P00469 P00469]
 +
** [http://www.uniprot.org/uniprot/O81395 O81395]
 +
** [http://www.uniprot.org/uniprot/Q05763 Q05763]
 +
** [http://www.uniprot.org/uniprot/Q39687 Q39687]
 +
** [http://www.uniprot.org/uniprot/Q9YTJ6 Q9YTJ6]
 +
** [http://www.uniprot.org/uniprot/P06785 P06785]
 +
** [http://www.uniprot.org/uniprot/P04818 P04818]
 +
** [http://www.uniprot.org/uniprot/P07607 P07607]
 +
** [http://www.uniprot.org/uniprot/P13100 P13100]
 +
{{#set: direction=LEFT-TO-RIGHT}}
 +
{{#set: common name=thymidylate synthase}}
 +
{{#set: ec number=EC-2.1.1.45}}
 +
{{#set: gene associated=Ec-27_004630}}
 +
{{#set: in pathway=PWY-7210|PWY-7198|PWY-7199|PWY-3841|1CMET2-PWY|PWY-7187|PWY0-166|PWY-7184}}
 +
{{#set: reconstruction category=annotation}}
 +
{{#set: reconstruction source=annotation-esiliculosus_genome}}
 +
{{#set: reconstruction tool=pathwaytools}}

Latest revision as of 20:41, 21 March 2018

Reaction THYMIDYLATESYN-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • thymidylate synthase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-7210, pyrimidine deoxyribonucleotides biosynthesis from CTP: PWY-7210
    • 8 reactions found over 8 reactions in the full pathway
  • PWY-7198, pyrimidine deoxyribonucleotides de novo biosynthesis IV: PWY-7198
    • 6 reactions found over 7 reactions in the full pathway
  • PWY-7199, pyrimidine deoxyribonucleosides salvage: PWY-7199
    • 1 reactions found over 5 reactions in the full pathway
  • PWY-3841, folate transformations II: PWY-3841
    • 10 reactions found over 11 reactions in the full pathway
  • 1CMET2-PWY, N10-formyl-tetrahydrofolate biosynthesis: 1CMET2-PWY
    • 9 reactions found over 9 reactions in the full pathway
  • PWY-7187, pyrimidine deoxyribonucleotides de novo biosynthesis II: PWY-7187
    • 6 reactions found over 7 reactions in the full pathway
  • PWY0-166, superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli): PWY0-166
    • 14 reactions found over 17 reactions in the full pathway
  • PWY-7184, pyrimidine deoxyribonucleotides de novo biosynthesis I: PWY-7184
    • 9 reactions found over 9 reactions in the full pathway

Reconstruction information

External links





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