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− | [[Category:Reaction]] | + | [[Category:Metabolite]] |
− | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=METHENYLTHFCYCLOHYDRO-RXN METHENYLTHFCYCLOHYDRO-RXN] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=Red-Thioredoxin Red-Thioredoxin] == |
− | * direction:
| + | |
− | ** REVERSIBLE
| + | |
| * common name: | | * common name: |
− | ** Tetrahydrofolate dehydrogenase/cyclohydrolase | + | ** a reduced thioredoxin |
− | ** Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
| + | |
− | * ec number:
| + | |
− | ** [http://enzyme.expasy.org/EC/3.5.4.9 EC-3.5.4.9]
| + | |
| * Synonym(s): | | * Synonym(s): |
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− | == Reaction Formula == | + | == Reaction(s) known to consume the compound == |
− | * With identifiers:
| + | * [[RXN0-5468]] |
− | ** 1 [[WATER]][c] '''+''' 1 [[5-10-METHENYL-THF-GLU-N]][c] '''<=>''' 1 [[PROTON]][c] '''+''' 1 [[FORMYL-THF-GLU-N]][c]
| + | * [[CDPREDUCT-RXN]] |
− | * With common name(s):
| + | * [[RIBONUCLEOSIDE-DIP-REDUCTI-RXN]] |
− | ** 1 H2O[c] '''+''' 1 a 5,10-methenyltetrahydrofolate[c] '''<=>''' 1 H+[c] '''+''' 1 an N10-formyl-tetrahydrofolate[c]
| + | * [[UDPREDUCT-RXN]] |
− | | + | * [[RXN-8668]] |
− | == Genes associated with this reaction ==
| + | * [[1.8.4.14-RXN]] |
− | Genes have been associated with this reaction based on different elements listed below.
| + | * [[THIOREDOXIN-RXN]] |
− | * [[Ec-15_001370]] | + | * [[GDPREDUCT-RXN]] |
− | ** ESILICULOSUS_GENOME
| + | == Reaction(s) known to produce the compound == |
− | ***AUTOMATED-NAME-MATCH
| + | * [[THIOREDOXIN-REDUCT-NADPH-RXN]] |
− | * [[Ec-14_004070]] | + | == Reaction(s) of unknown directionality == |
− | ** ESILICULOSUS_GENOME
| + | * [[ADPREDUCT-RXN]] |
− | ***AUTOMATED-NAME-MATCH
| + | * [[1.8.4.12-RXN]] |
− | == Pathways ==
| + | * [[1.17.4.2-RXN]] |
− | * [[PWY-1722]], formate assimilation into 5,10-methylenetetrahydrofolate: [http://metacyc.org/META/NEW-IMAGE?object=PWY-1722 PWY-1722] | + | * [[1.8.4.8-RXN]] |
− | ** '''3''' reactions found over '''3''' reactions in the full pathway
| + | |
− | * [[PWY-3841]], folate transformations II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-3841 PWY-3841] | + | |
− | ** '''10''' reactions found over '''11''' reactions in the full pathway
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− | * [[1CMET2-PWY]], N10-formyl-tetrahydrofolate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=1CMET2-PWY 1CMET2-PWY] | + | |
− | ** '''9''' reactions found over '''9''' reactions in the full pathway
| + | |
− | * [[PWY-5030]], L-histidine degradation III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5030 PWY-5030] | + | |
− | ** '''2''' reactions found over '''6''' reactions in the full pathway
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− | * [[P164-PWY]], purine nucleobases degradation I (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=P164-PWY P164-PWY] | + | |
− | ** '''4''' reactions found over '''17''' reactions in the full pathway
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− | * [[CODH-PWY]], reductive acetyl coenzyme A pathway I (homoacetogenic bacteria): [http://metacyc.org/META/NEW-IMAGE?object=CODH-PWY CODH-PWY] | + | |
− | ** '''5''' reactions found over '''9''' reactions in the full pathway
| + | |
− | * [[PWY-5497]], purine nucleobases degradation II (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5497 PWY-5497] | + | |
− | ** '''8''' reactions found over '''24''' reactions in the full pathway
| + | |
− | * [[PWY-2201]], folate transformations I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-2201 PWY-2201] | + | |
− | ** '''12''' reactions found over '''12''' reactions in the full pathway
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− | * [[PWY-6613]], tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6613 PWY-6613] | + | |
− | ** '''1''' reactions found over '''2''' reactions in the full pathway
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− | == Reconstruction information ==
| + | |
− | * Category: [[annotation]]
| + | |
− | ** Source: [[annotation-esiliculosus_genome]] | + | |
− | *** Tool: [[pathwaytools]] | + | |
| == External links == | | == External links == |
− | * RHEA:
| + | {{#set: common name=a reduced thioredoxin}} |
− | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=23700 23700]
| + | {{#set: consumed by=RXN0-5468|CDPREDUCT-RXN|RIBONUCLEOSIDE-DIP-REDUCTI-RXN|UDPREDUCT-RXN|RXN-8668|1.8.4.14-RXN|THIOREDOXIN-RXN|GDPREDUCT-RXN}} |
− | * LIGAND-RXN:
| + | {{#set: produced by=THIOREDOXIN-REDUCT-NADPH-RXN}} |
− | ** [http://www.genome.jp/dbget-bin/www_bget?R01655 R01655]
| + | {{#set: reversible reaction associated=ADPREDUCT-RXN|1.8.4.12-RXN|1.17.4.2-RXN|1.8.4.8-RXN}} |
− | * UNIPROT:
| + | |
− | ** [http://www.uniprot.org/uniprot/P09440 P09440]
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− | ** [http://www.uniprot.org/uniprot/P07245 P07245]
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− | ** [http://www.uniprot.org/uniprot/P11586 P11586]
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− | ** [http://www.uniprot.org/uniprot/P18155 P18155]
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− | ** [http://www.uniprot.org/uniprot/P44313 P44313]
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− | ** [http://www.uniprot.org/uniprot/P47259 P47259]
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− | ** [http://www.uniprot.org/uniprot/P13995 P13995]
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− | ** [http://www.uniprot.org/uniprot/P54382 P54382]
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− | ** [http://www.uniprot.org/uniprot/O67736 O67736]
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− | ** [http://www.uniprot.org/uniprot/Q9JWI9 Q9JWI9]
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− | ** [http://www.uniprot.org/uniprot/Q9PP68 Q9PP68]
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− | ** [http://www.uniprot.org/uniprot/P24186 P24186]
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− | ** [http://www.uniprot.org/uniprot/Q04448 Q04448]
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− | ** [http://www.uniprot.org/uniprot/Q60006 Q60006]
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− | ** [http://www.uniprot.org/uniprot/Q27772 Q27772]
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− | ** [http://www.uniprot.org/uniprot/P51696 P51696]
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− | ** [http://www.uniprot.org/uniprot/O68031 O68031]
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− | ** [http://www.uniprot.org/uniprot/Q9ZTV0 Q9ZTV0]
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− | ** [http://www.uniprot.org/uniprot/Q9X7F6 Q9X7F6]
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− | {{#set: direction=REVERSIBLE}}
| + | |
− | {{#set: common name=Tetrahydrofolate dehydrogenase/cyclohydrolase}} | + | |
− | {{#set: common name=Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain}} | + | |
− | {{#set: ec number=EC-3.5.4.9}}
| + | |
− | {{#set: gene associated=Ec-15_001370|Ec-14_004070}}
| + | |
− | {{#set: in pathway=PWY-1722|PWY-3841|1CMET2-PWY|PWY-5030|P164-PWY|CODH-PWY|PWY-5497|PWY-2201|PWY-6613}}
| + | |
− | {{#set: reconstruction category=annotation}} | + | |
− | {{#set: reconstruction source=annotation-esiliculosus_genome}} | + | |
− | {{#set: reconstruction tool=pathwaytools}}
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