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− | [[Category:Reaction]] | + | [[Category:Pathway]] |
− | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=1.1.1.34-RXN 1.1.1.34-RXN] == | + | == Pathway [http://metacyc.org/META/NEW-IMAGE?object=PWY66-388 PWY66-388] == |
− | * direction: | + | * taxonomic range: |
− | ** REVERSIBLE | + | ** [http://metacyc.org/META/NEW-IMAGE?object=TAX-33208 TAX-33208] |
| * common name: | | * common name: |
− | ** hydroxymethylglutaryl-CoA reductase (NADPH) | + | ** fatty acid α-oxidation III |
− | ** Hydroxymethylglutaryl-CoA reductase, class I/II
| + | |
− | ** Hydroxymethylglutaryl-CoA reductase, N-terminal
| + | |
− | * ec number:
| + | |
− | ** [http://enzyme.expasy.org/EC/1.1.1.34 EC-1.1.1.34]
| + | |
| * Synonym(s): | | * Synonym(s): |
| | | |
− | == Reaction Formula == | + | == Reaction(s) found == |
− | * With identifiers:
| + | '''4''' reactions found over '''7''' reactions in the full pathway |
− | ** 2 [[NADP]][c] '''+''' 1 [[CO-A]][c] '''+''' 1 [[MEVALONATE]][c] '''<=>''' 1 [[3-HYDROXY-3-METHYL-GLUTARYL-COA]][c] '''+''' 2 [[PROTON]][c] '''+''' 2 [[NADPH]][c]
| + | * [[CERAMIDASE-YEAST-RXN]] |
− | * With common name(s): | + | ** 1 associated gene(s): |
− | ** 2 NADP+[c] '''+''' 1 coenzyme A[c] '''+''' 1 (R)-mevalonate[c] '''<=>''' 1 (S)-3-hydroxy-3-methylglutaryl-CoA[c] '''+''' 2 H+[c] '''+''' 2 NADPH[c] | + | *** [[Ec-26_006010]] |
− | | + | ** 1 reconstruction source(s) associated: |
− | == Genes associated with this reaction ==
| + | *** [[annotation-esiliculosus_genome]] |
− | Genes have been associated with this reaction based on different elements listed below.
| + | * [[RXN66-474]] |
− | * [[Ec-03_000580]] | + | ** 0 associated gene: |
− | ** ESILICULOSUS_GENOME | + | ** 1 reconstruction source(s) associated: |
− | ***EC-NUMBER | + | *** [[annotation-esiliculosus_genome]] |
− | * [[Ec-03_000570]] | + | * [[RXN66-476]] |
− | ** ESILICULOSUS_GENOME | + | ** 0 associated gene: |
− | ***EC-NUMBER | + | ** 1 reconstruction source(s) associated: |
− | ** [[pantograph]]-[[aragem]] | + | *** [[annotation-esiliculosus_genome]] |
− | * [[Ec-08_002990]] | + | * [[RXN66-477]] |
− | ** ESILICULOSUS_GENOME | + | ** 4 associated gene(s): |
− | ***EC-NUMBER | + | *** [[Ec-01_001560]] |
− | ** [[pantograph]]-[[aragem]] | + | *** [[Ec-03_003710]] |
− | * [[Ec-27_005710]] | + | *** [[Ec-12_008720]] |
− | ** ESILICULOSUS_GENOME | + | *** [[Ec-02_006430]] |
− | ***GO-TERM | + | ** 1 reconstruction source(s) associated: |
− | == Pathways == | + | *** [[annotation-esiliculosus_genome]] |
− | * [[PWY-922]], mevalonate pathway I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-922 PWY-922] | + | == Reaction(s) not found == |
− | ** '''7''' reactions found over '''7''' reactions in the full pathway
| + | * [http://metacyc.org/META/NEW-IMAGE?object=FORMYL-COA-HYDROLASE-RXN FORMYL-COA-HYDROLASE-RXN] |
− | * [[PWY-6174]], mevalonate pathway II (archaea): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6174 PWY-6174]
| + | * [http://metacyc.org/META/NEW-IMAGE?object=RXN3O-4042 RXN3O-4042] |
− | ** '''5''' reactions found over '''7''' reactions in the full pathway | + | * [http://metacyc.org/META/NEW-IMAGE?object=RXN66-475 RXN66-475] |
− | * [[PWY-7391]], isoprene biosynthesis II (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7391 PWY-7391]
| + | |
− | ** '''7''' reactions found over '''8''' reactions in the full pathway | + | |
− | * [[PWY-7524]], mevalonate pathway III (archaea): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7524 PWY-7524]
| + | |
− | ** '''4''' reactions found over '''8''' reactions in the full pathway
| + | |
− | == Reconstruction information ==
| + | |
− | * Category: [[orthology]]
| + | |
− | ** Source: [[orthology-aragem]]
| + | |
− | *** Tool: [[pantograph]]
| + | |
− | * Category: [[annotation]]
| + | |
− | ** Source: [[annotation-esiliculosus_genome]]
| + | |
− | *** Tool: [[pathwaytools]]
| + | |
| == External links == | | == External links == |
− | * RHEA:
| + | {{#set: taxonomic range=TAX-33208}} |
− | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=15989 15989]
| + | {{#set: common name=fatty acid α-oxidation III}} |
− | * LIGAND-RXN:
| + | {{#set: reaction found=4}} |
− | ** [http://www.genome.jp/dbget-bin/www_bget?R02082 R02082]
| + | {{#set: total reaction=7}} |
− | * UNIPROT:
| + | {{#set: completion rate=57.0}} |
− | ** [http://www.uniprot.org/uniprot/P16393 P16393]
| + | |
− | ** [http://www.uniprot.org/uniprot/P14891 P14891]
| + | |
− | ** [http://www.uniprot.org/uniprot/P16237 P16237]
| + | |
− | ** [http://www.uniprot.org/uniprot/P20715 P20715]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q59468 Q59468]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q01237 Q01237]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q61671 Q61671]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q944T9 Q944T9]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9S9C2 Q9S9C2]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9S999 Q9S999]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9S998 Q9S998]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9S997 Q9S997]
| + | |
− | ** [http://www.uniprot.org/uniprot/P04035 P04035]
| + | |
− | ** [http://www.uniprot.org/uniprot/P00347 P00347]
| + | |
− | ** [http://www.uniprot.org/uniprot/P29058 P29058]
| + | |
− | ** [http://www.uniprot.org/uniprot/P29057 P29057]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q12577 Q12577]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q12649 Q12649]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q00583 Q00583]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q01559 Q01559]
| + | |
− | ** [http://www.uniprot.org/uniprot/P48022 P48022]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q43825 Q43825]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q43826 Q43826]
| + | |
− | ** [http://www.uniprot.org/uniprot/P14773 P14773]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q7M4W2 Q7M4W2]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q7M4W1 Q7M4W1]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q7M4W4 Q7M4W4]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q7M4W3 Q7M4W3]
| + | |
− | ** [http://www.uniprot.org/uniprot/P48019 P48019]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q41454 Q41454]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q42506 Q42506]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q41455 Q41455]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q41456 Q41456]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q41458 Q41458]
| + | |
− | ** [http://www.uniprot.org/uniprot/P48020 P48020]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9FS01 Q9FS01]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q42466 Q42466]
| + | |
− | ** [http://www.uniprot.org/uniprot/O48624 O48624]
| + | |
− | ** [http://www.uniprot.org/uniprot/O04188 O04188]
| + | |
− | ** [http://www.uniprot.org/uniprot/O24594 O24594]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q41438 Q41438]
| + | |
− | ** [http://www.uniprot.org/uniprot/O64966 O64966]
| + | |
− | ** [http://www.uniprot.org/uniprot/O64967 O64967]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q03163 Q03163]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q39628 Q39628]
| + | |
− | ** [http://www.uniprot.org/uniprot/P93514 P93514]
| + | |
− | ** [http://www.uniprot.org/uniprot/O08424 O08424]
| + | |
− | {{#set: direction=REVERSIBLE}} | + | |
− | {{#set: common name=hydroxymethylglutaryl-CoA reductase (NADPH)}} | + | |
− | {{#set: common name=Hydroxymethylglutaryl-CoA reductase, class I/II}} | + | |
− | {{#set: common name=Hydroxymethylglutaryl-CoA reductase, N-terminal}} | + | |
− | {{#set: ec number=EC-1.1.1.34}} | + | |
− | {{#set: gene associated=Ec-03_000580|Ec-03_000570|Ec-08_002990|Ec-27_005710}}
| + | |
− | {{#set: in pathway=PWY-922|PWY-6174|PWY-7391|PWY-7524}}
| + | |
− | {{#set: reconstruction category=orthology|annotation}}
| + | |
− | {{#set: reconstruction source=annotation-esiliculosus_genome|orthology-aragem}}
| + | |
− | {{#set: reconstruction tool=pantograph|pathwaytools}}
| + | |