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| [[Category:Reaction]] | | [[Category:Reaction]] |
− | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=CITSYN-RXN CITSYN-RXN] == | + | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-13162 RXN-13162] == |
| * direction: | | * direction: |
| ** LEFT-TO-RIGHT | | ** LEFT-TO-RIGHT |
| + | * common name: |
| + | ** Isopentenyl-diphosphate delta-isomerase type 1 fused to squalene synthase; probably two separate ORFs |
| * ec number: | | * ec number: |
− | ** [http://enzyme.expasy.org/EC/2.3.3.16 EC-2.3.3.16] | + | ** [http://enzyme.expasy.org/EC/2.5.1.21 EC-2.5.1.21] |
− | ** [http://enzyme.expasy.org/EC/2.3.3.1 EC-2.3.3.1]
| + | |
| * Synonym(s): | | * Synonym(s): |
− | ** Condensing enzyme
| |
− | ** citrate synthesis
| |
| | | |
| == Reaction Formula == | | == Reaction Formula == |
| * With identifiers: | | * With identifiers: |
− | ** 1 [[ACETYL-COA]][c] '''+''' 1 [[WATER]][c] '''+''' 1 [[OXALACETIC_ACID]][c] '''=>''' 1 [[CO-A]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[CIT]][c] | + | ** 2 [[FARNESYL-PP]][c] '''+''' 1 [[NADH-P-OR-NOP]][c] '''+''' 1 [[PROTON]][c] '''=>''' 1 [[SQUALENE]][c] '''+''' 2 [[PPI]][c] '''+''' 1 [[NAD-P-OR-NOP]][c] |
| * With common name(s): | | * With common name(s): |
− | ** 1 acetyl-CoA[c] '''+''' 1 H2O[c] '''+''' 1 oxaloacetate[c] '''=>''' 1 coenzyme A[c] '''+''' 1 H+[c] '''+''' 1 citrate[c] | + | ** 2 (2E,6E)-farnesyl diphosphate[c] '''+''' 1 NAD(P)H[c] '''+''' 1 H+[c] '''=>''' 1 squalene[c] '''+''' 2 diphosphate[c] '''+''' 1 NAD(P)+[c] |
| | | |
| == Genes associated with this reaction == | | == Genes associated with this reaction == |
| + | Genes have been associated with this reaction based on different elements listed below. |
| + | * Gene: [[Ec-11_001030]] |
| + | ** Source: [[annotation-esiliculosus_genome]] |
| + | *** Assignment: EC-NUMBER |
| == Pathways == | | == Pathways == |
− | * [[FERMENTATION-PWY]], mixed acid fermentation: [http://metacyc.org/META/NEW-IMAGE?object=FERMENTATION-PWY FERMENTATION-PWY]
| + | * [[PWY-5670]], epoxysqualene biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5670 PWY-5670] |
− | ** '''8''' reactions found over '''16''' reactions in the full pathway
| + | ** '''2''' reactions found over '''2''' reactions in the full pathway |
− | * [[PWY-5750]], itaconate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5750 PWY-5750] | + | |
− | ** '''3''' reactions found over '''4''' reactions in the full pathway | + | |
− | * [[PWY-5913]], partial TCA cycle (obligate autotrophs): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5913 PWY-5913]
| + | |
− | ** '''10''' reactions found over '''11''' reactions in the full pathway
| + | |
− | * [[PWY-5690]], TCA cycle II (plants and fungi): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5690 PWY-5690]
| + | |
− | ** '''8''' reactions found over '''9''' reactions in the full pathway
| + | |
− | * [[PWY-6549]], L-glutamine biosynthesis III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6549 PWY-6549]
| + | |
− | ** '''8''' reactions found over '''9''' reactions in the full pathway
| + | |
− | * [[P105-PWY]], TCA cycle IV (2-oxoglutarate decarboxylase): [http://metacyc.org/META/NEW-IMAGE?object=P105-PWY P105-PWY]
| + | |
− | ** '''9''' reactions found over '''11''' reactions in the full pathway
| + | |
− | * [[GLYOXYLATE-BYPASS]], glyoxylate cycle: [http://metacyc.org/META/NEW-IMAGE?object=GLYOXYLATE-BYPASS GLYOXYLATE-BYPASS]
| + | |
− | ** '''6''' reactions found over '''6''' reactions in the full pathway
| + | |
− | * [[PWY-6969]], TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6969 PWY-6969]
| + | |
− | ** '''10''' reactions found over '''12''' reactions in the full pathway
| + | |
− | * [[PWY-6728]], methylaspartate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6728 PWY-6728]
| + | |
− | ** '''11''' reactions found over '''18''' reactions in the full pathway
| + | |
− | * [[REDCITCYC]], TCA cycle VIII (helicobacter): [http://metacyc.org/META/NEW-IMAGE?object=REDCITCYC REDCITCYC]
| + | |
− | ** '''5''' reactions found over '''9''' reactions in the full pathway
| + | |
− | * [[PWY-7254]], TCA cycle VII (acetate-producers): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7254 PWY-7254]
| + | |
− | ** '''7''' reactions found over '''9''' reactions in the full pathway
| + | |
− | * [[PWY-7124]], ethylene biosynthesis V (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7124 PWY-7124]
| + | |
− | ** '''8''' reactions found over '''10''' reactions in the full pathway
| + | |
− | * [[PWY66-398]], TCA cycle III (animals): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-398 PWY66-398]
| + | |
− | ** '''10''' reactions found over '''11''' reactions in the full pathway
| + | |
− | * [[TCA]], TCA cycle I (prokaryotic): [http://metacyc.org/META/NEW-IMAGE?object=TCA TCA]
| + | |
− | ** '''9''' reactions found over '''10''' reactions in the full pathway
| + | |
| == Reconstruction information == | | == Reconstruction information == |
− | * [[annotation]]: | + | * Category: [[annotation]] |
− | ** [[pathwaytools]]: | + | ** Source: [[annotation-esiliculosus_genome]] |
− | *** [[esiliculosus_genome]] | + | *** Tool: [[pathwaytools]] |
| == External links == | | == External links == |
| * RHEA: | | * RHEA: |
− | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=16845 16845] | + | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=32302 32302] |
| + | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=32296 32296] |
| * LIGAND-RXN: | | * LIGAND-RXN: |
− | ** [http://www.genome.jp/dbget-bin/www_bget?R00351 R00351] | + | ** [http://www.genome.jp/dbget-bin/www_bget?R06223 R06223] |
− | * PIR:
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A43936 A43936]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A81200 A81200]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=B81139 B81139]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=E64760 E64760]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=F86708 F86708]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=G69600 G69600]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=G81265 G81265]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=I39506 I39506]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=I40044 I40044]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=I40380 I40380]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=I40717 I40717]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=JQ1392 JQ1392]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=PQ0046 PQ0046]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S41527 S41527]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S41563 S41563]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S42370 S42370]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S44316 S44316]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S52814 S52814]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T02390 T02390]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T09334 T09334]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T44615 T44615]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKBY YKBY]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKBYC YKBYC]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKEC YKEC]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKMUM YKMUM]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKMY YKMY]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKPG YKPG]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKPSCA YKPSCA]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKQPC YKQPC]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKRECP YKRECP]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKYT YKYT]
| + | |
− | * UNIPROT:
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9JRA5 Q9JRA5]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9JQX0 Q9JQX0]
| + | |
− | ** [http://www.uniprot.org/uniprot/P31660 P31660]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9CHQ6 Q9CHQ6]
| + | |
− | ** [http://www.uniprot.org/uniprot/P39120 P39120]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9PLZ5 Q9PLZ5]
| + | |
− | ** [http://www.uniprot.org/uniprot/P20902 P20902]
| + | |
− | ** [http://www.uniprot.org/uniprot/P51033 P51033]
| + | |
− | ** [http://www.uniprot.org/uniprot/P39119 P39119]
| + | |
− | ** [http://www.uniprot.org/uniprot/P42457 P42457]
| + | |
− | ** [http://www.uniprot.org/uniprot/P18789 P18789]
| + | |
− | ** [http://www.uniprot.org/uniprot/P20903 P20903]
| + | |
− | ** [http://www.uniprot.org/uniprot/P51038 P51038]
| + | |
− | ** [http://www.uniprot.org/uniprot/P34085 P34085]
| + | |
− | ** [http://www.uniprot.org/uniprot/P34575 P34575]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q43175 Q43175]
| + | |
− | ** [http://www.uniprot.org/uniprot/P43635 P43635]
| + | |
− | ** [http://www.uniprot.org/uniprot/O24259 O24259]
| + | |
− | ** [http://www.uniprot.org/uniprot/O32705 O32705]
| + | |
− | ** [http://www.uniprot.org/uniprot/P00890 P00890]
| + | |
− | ** [http://www.uniprot.org/uniprot/P08679 P08679]
| + | |
− | ** [http://www.uniprot.org/uniprot/P0ABH7 P0ABH7]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q47237 Q47237]
| + | |
− | ** [http://www.uniprot.org/uniprot/P20115 P20115]
| + | |
− | ** [http://www.uniprot.org/uniprot/P26491 P26491]
| + | |
− | ** [http://www.uniprot.org/uniprot/P00889 P00889]
| + | |
− | ** [http://www.uniprot.org/uniprot/P20901 P20901]
| + | |
− | ** [http://www.uniprot.org/uniprot/P09948 P09948]
| + | |
− | ** [http://www.uniprot.org/uniprot/P21553 P21553]
| + | |
| {{#set: direction=LEFT-TO-RIGHT}} | | {{#set: direction=LEFT-TO-RIGHT}} |
− | {{#set: ec number=EC-2.3.3.16}} | + | {{#set: common name=Isopentenyl-diphosphate delta-isomerase type 1 fused to squalene synthase; probably two separate ORFs}} |
− | {{#set: ec number=EC-2.3.3.1}} | + | {{#set: ec number=EC-2.5.1.21}} |
− | {{#set: common name=Condensing enzyme|citrate synthesis}} | + | {{#set: gene associated=Ec-11_001030}} |
− | {{#set: in pathway=FERMENTATION-PWY|PWY-5750|PWY-5913|PWY-5690|PWY-6549|P105-PWY|GLYOXYLATE-BYPASS|PWY-6969|PWY-6728|REDCITCYC|PWY-7254|PWY-7124|PWY66-398|TCA}} | + | {{#set: in pathway=PWY-5670}} |
| {{#set: reconstruction category=annotation}} | | {{#set: reconstruction category=annotation}} |
| + | {{#set: reconstruction source=annotation-esiliculosus_genome}} |
| {{#set: reconstruction tool=pathwaytools}} | | {{#set: reconstruction tool=pathwaytools}} |
− | {{#set: reconstruction source=esiliculosus_genome}}
| |
Genes have been associated with this reaction based on different elements listed below.