Difference between revisions of "KYNURENINE-3-MONOOXYGENASE-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLUTCYSLIG-RXN GLUTCYSLIG-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** Glutamate-cystein...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=KYNURENINE-3-MONOOXYGENASE-RXN KYNURENINE-3-MONOOXYGENASE-RXN] == * direction: ** LEFT-TO-RIGHT * c...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLUTCYSLIG-RXN GLUTCYSLIG-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=KYNURENINE-3-MONOOXYGENASE-RXN KYNURENINE-3-MONOOXYGENASE-RXN] ==
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
−
** Glutamate-cysteine ligase catalytic subunit
+
** Monooxygenase, FAD-binding
−
** glutamate-cysteine ligase
+
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/6.3.2.2 EC-6.3.2.2]
+
** [http://enzyme.expasy.org/EC/1.14.13.9 EC-1.14.13.9]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[CYS]][c] '''+''' 1 [[ATP]][c] '''+''' 1 [[GLT]][c] '''=>''' 1 [[PROTON]][c] '''+''' 1 [[L-GAMMA-GLUTAMYLCYSTEINE]][c] '''+''' 1 [[ADP]][c] '''+''' 1 [[Pi]][c]
+
** 1 [[PROTON]][c] '''+''' 1 [[CPD-14736]][c] '''+''' 1 [[NADPH]][c] '''+''' 1 [[OXYGEN-MOLECULE]][c] '''=>''' 1 [[WATER]][c] '''+''' 1 [[NADP]][c] '''+''' 1 [[3-HYDROXY-L-KYNURENINE]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 L-cysteine[c] '''+''' 1 ATP[c] '''+''' 1 L-glutamate[c] '''=>''' 1 H+[c] '''+''' 1 γ-L-glutamyl-L-cysteine[c] '''+''' 1 ADP[c] '''+''' 1 phosphate[c]
+
** 1 H+[c] '''+''' 1 L-kynurenine[c] '''+''' 1 NADPH[c] '''+''' 1 oxygen[c] '''=>''' 1 H2O[c] '''+''' 1 NADP+[c] '''+''' 1 3-hydroxy-L-kynurenine[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* Gene: [[Ec-05_001730]]
+
* Gene: [[Ec-26_002430]]
 
** Source: [[annotation-esiliculosus_genome]]
 
** Source: [[annotation-esiliculosus_genome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
−
* Gene: [[Ec-17_001900]]
+
* Gene: [[Ec-26_001830]]
 
** Source: [[annotation-esiliculosus_genome]]
 
** Source: [[annotation-esiliculosus_genome]]
−
*** Assignment: GO-TERM
+
*** Assignment: EC-NUMBER
 +
* Gene: [[Ec-28_001680]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: EC-NUMBER
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-6840]], homoglutathione biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6840 PWY-6840]
+
* [[PWY-7765]], 3-hydroxy-4-methyl-anthranilate biosynthesis II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7765 PWY-7765]
−
** '''1''' reactions found over '''2''' reactions in the full pathway
+
** '''2''' reactions found over '''5''' reactions in the full pathway
−
* [[PWY-7255]], ergothioneine biosynthesis I (bacteria): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7255 PWY-7255]
+
* [[PWY-5651]], L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5651 PWY-5651]
−
** '''1''' reactions found over '''6''' reactions in the full pathway
+
** '''2''' reactions found over '''5''' reactions in the full pathway
−
* [[GLUTATHIONESYN-PWY]], glutathione biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=GLUTATHIONESYN-PWY GLUTATHIONESYN-PWY]
+
* [[PWY-6309]], L-tryptophan degradation XI (mammalian, via kynurenine): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6309 PWY-6309]
−
** '''2''' reactions found over '''2''' reactions in the full pathway
+
** '''8''' reactions found over '''17''' reactions in the full pathway
 +
* [[PWY-7717]], 3-hydroxy-4-methyl-anthranilate biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7717 PWY-7717]
 +
** '''2''' reactions found over '''6''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[annotation]]
 
* Category: [[annotation]]
Line 37: Line 41:
 
== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=13285 13285]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=20545 20545]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R00894 R00894]
+
** [http://www.genome.jp/dbget-bin/www_bget?R01960 R01960]
−
* UNIPROT:
+
−
** [http://www.uniprot.org/uniprot/P19468 P19468]
+
−
** [http://www.uniprot.org/uniprot/Q56277 Q56277]
+
−
** [http://www.uniprot.org/uniprot/Q9JZI4 Q9JZI4]
+
−
** [http://www.uniprot.org/uniprot/Q9JU83 Q9JU83]
+
−
** [http://www.uniprot.org/uniprot/P48507 P48507]
+
−
** [http://www.uniprot.org/uniprot/P48506 P48506]
+
−
** [http://www.uniprot.org/uniprot/P32477 P32477]
+
−
** [http://www.uniprot.org/uniprot/P0A6W9 P0A6W9]
+
−
** [http://www.uniprot.org/uniprot/O22493 O22493]
+
−
** [http://www.uniprot.org/uniprot/P46309 P46309]
+
−
** [http://www.uniprot.org/uniprot/Q9TY17 Q9TY17]
+
−
** [http://www.uniprot.org/uniprot/Q09768 Q09768]
+
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
−
{{#set: common name=Glutamate-cysteine ligase catalytic subunit}}
+
{{#set: common name=Monooxygenase, FAD-binding}}
−
{{#set: common name=glutamate-cysteine ligase}}
+
{{#set: ec number=EC-1.14.13.9}}
−
{{#set: ec number=EC-6.3.2.2}}
+
{{#set: gene associated=Ec-26_002430|Ec-26_001830|Ec-28_001680}}
−
{{#set: gene associated=Ec-05_001730|Ec-17_001900}}
+
{{#set: in pathway=PWY-7765|PWY-5651|PWY-6309|PWY-7717}}
−
{{#set: in pathway=PWY-6840|PWY-7255|GLUTATHIONESYN-PWY}}
+
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction source=annotation-esiliculosus_genome}}
 
{{#set: reconstruction source=annotation-esiliculosus_genome}}
 
{{#set: reconstruction tool=pathwaytools}}
 
{{#set: reconstruction tool=pathwaytools}}

Latest revision as of 19:48, 21 March 2018

Reaction KYNURENINE-3-MONOOXYGENASE-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • Monooxygenase, FAD-binding
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-7765, 3-hydroxy-4-methyl-anthranilate biosynthesis II: PWY-7765
    • 2 reactions found over 5 reactions in the full pathway
  • PWY-5651, L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde: PWY-5651
    • 2 reactions found over 5 reactions in the full pathway
  • PWY-6309, L-tryptophan degradation XI (mammalian, via kynurenine): PWY-6309
    • 8 reactions found over 17 reactions in the full pathway
  • PWY-7717, 3-hydroxy-4-methyl-anthranilate biosynthesis I: PWY-7717
    • 2 reactions found over 6 reactions in the full pathway

Reconstruction information

External links





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