Difference between revisions of "PYRUVDEH-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=5-OXOPROLINE 5-OXOPROLINE] == * smiles: ** C(=O)(C1(NC(CC1)=O))[O-] * inchi key: ** InChIKey=OD...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=PYRUVDEH-RXN PYRUVDEH-RXN] == * direction: ** LEFT-TO-RIGHT * ec number: ** [http://enzyme.expasy.o...")
 
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[[Category:Metabolite]]
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[[Category:Reaction]]
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=5-OXOPROLINE 5-OXOPROLINE] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=PYRUVDEH-RXN PYRUVDEH-RXN] ==
* smiles:
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* direction:
** C(=O)(C1(NC(CC1)=O))[O-]
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** LEFT-TO-RIGHT
* inchi key:
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* ec number:
** InChIKey=ODHCTXKNWHHXJC-VKHMYHEASA-M
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** [http://enzyme.expasy.org/EC/1.2.1 EC-1.2.1]
* common name:
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** 5-oxo-L-proline
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* molecular weight:
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** 128.107   
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* Synonym(s):
 
* Synonym(s):
** pyrrolidone-COO
 
** pyrrolidone-carboxylate
 
** L-5-pyrrolidone-2-carboxylic acid
 
** L-pyroglutamic acid
 
** 5-oxo-L-proline
 
** pyroglutamic acid
 
** pyroglutamate
 
** 5-pyrrolidone-2-carboxylic acid
 
** L-pyroglutamate
 
** Pidolic acid
 
  
== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
* [[5-OXOPROLINASE-ATP-HYDROLYSING-RXN]]
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* With identifiers:
== Reaction(s) known to produce the compound ==
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** 1 [[PYRUVATE]][c] '''+''' 1 [[NAD]][c] '''+''' 1 [[CO-A]][c] '''=>''' 1 [[ACETYL-COA]][c] '''+''' 1 [[CARBON-DIOXIDE]][c] '''+''' 1 [[NADH]][c]
* [[GAMMA-GLUTAMYLCYCLOTRANSFERASE-RXN]]
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* With common name(s):
* [[RXN-15681]]
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** 1 pyruvate[c] '''+''' 1 NAD+[c] '''+''' 1 coenzyme A[c] '''=>''' 1 acetyl-CoA[c] '''+''' 1 CO2[c] '''+''' 1 NADH[c]
== Reaction(s) of unknown directionality ==
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[Ec-27_004160]]
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** Source: [[orthology-aragem]]
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** Source: [[orthology-aragem]]
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* Gene: [[Ec-25_000140]]
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** Source: [[orthology-aragem]]
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** Source: [[orthology-aragem]]
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* Gene: [[Ec-25_000020]]
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** Source: [[orthology-aragem]]
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** Source: [[orthology-aragem]]
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* Gene: [[Ec-01_010530]]
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** Source: [[orthology-aragem]]
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** Source: [[orthology-aragem]]
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* Gene: [[Ec-23_002710]]
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** Source: [[orthology-aragem]]
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* Gene: [[Ec-27_000530]]
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** Source: [[orthology-aragem]]
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* Gene: [[Ec-18_000080]]
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** Source: [[orthology-aragem]]
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** Source: [[orthology-aragem]]
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* Gene: [[Ec-18_003420]]
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** Source: [[orthology-aragem]]
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== Pathways  ==
 +
* [[PWY-7218]], photosynthetic 3-hydroxybutanoate biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7218 PWY-7218]
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** '''7''' reactions found over '''10''' reactions in the full pathway
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* [[PWY-7384]], anaerobic energy metabolism (invertebrates, mitochondrial): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7384 PWY-7384]
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** '''6''' reactions found over '''12''' reactions in the full pathway
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* [[PWY-6886]], 1-butanol autotrophic biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6886 PWY-6886]
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** '''8''' reactions found over '''11''' reactions in the full pathway
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* [[PWY-5537]], pyruvate fermentation to acetate V: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5537 PWY-5537]
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** '''2''' reactions found over '''4''' reactions in the full pathway
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* [[GLYCOLYSIS-TCA-GLYOX-BYPASS]], superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass: [http://metacyc.org/META/NEW-IMAGE?object=GLYCOLYSIS-TCA-GLYOX-BYPASS GLYCOLYSIS-TCA-GLYOX-BYPASS]
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** '''3''' reactions found over '''5''' reactions in the full pathway
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* [[PWY-5482]], pyruvate fermentation to acetate II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5482 PWY-5482]
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** '''1''' reactions found over '''3''' reactions in the full pathway
 +
== Reconstruction information  ==
 +
* Category: [[orthology]]
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** Source: [[orthology-aragem]]
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*** Tool: [[pantograph]]
 
== External links  ==
 
== External links  ==
* CAS : 98-79-3
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* RHEA:
* PUBCHEM:
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=28042 28042]
** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5289118 5289118]
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* LIGAND-RXN:
* HMDB : HMDB00267
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** [http://www.genome.jp/dbget-bin/www_bget?R00209 R00209]
* LIGAND-CPD:
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{{#set: direction=LEFT-TO-RIGHT}}
** [http://www.genome.jp/dbget-bin/www_bget?C01879 C01879]
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{{#set: ec number=EC-1.2.1}}
* CHEMSPIDER:
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{{#set: gene associated=Ec-27_004160|Ec-25_000140|Ec-25_000020|Ec-01_010530|Ec-23_002710|Ec-27_000530|Ec-18_000080|Ec-18_003420}}
** [http://www.chemspider.com/Chemical-Structure.4451146.html 4451146]
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{{#set: in pathway=PWY-7218|PWY-7384|PWY-6886|PWY-5537|GLYCOLYSIS-TCA-GLYOX-BYPASS|PWY-5482}}
* CHEBI:
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{{#set: reconstruction category=orthology}}
** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=58402 58402]
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{{#set: reconstruction source=orthology-aragem}}
{{#set: smiles=C(=O)(C1(NC(CC1)=O))[O-]}}
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{{#set: reconstruction tool=pantograph}}
{{#set: inchi key=InChIKey=ODHCTXKNWHHXJC-VKHMYHEASA-M}}
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{{#set: common name=5-oxo-L-proline}}
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{{#set: molecular weight=128.107    }}
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{{#set: common name=pyrrolidone-COO|pyrrolidone-carboxylate|L-5-pyrrolidone-2-carboxylic acid|L-pyroglutamic acid|5-oxo-L-proline|pyroglutamic acid|pyroglutamate|5-pyrrolidone-2-carboxylic acid|L-pyroglutamate|Pidolic acid}}
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{{#set: consumed by=5-OXOPROLINASE-ATP-HYDROLYSING-RXN}}
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{{#set: produced by=GAMMA-GLUTAMYLCYCLOTRANSFERASE-RXN|RXN-15681}}
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Latest revision as of 19:17, 21 March 2018

Reaction PYRUVDEH-RXN

  • direction:
    • LEFT-TO-RIGHT
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 pyruvate[c] + 1 NAD+[c] + 1 coenzyme A[c] => 1 acetyl-CoA[c] + 1 CO2[c] + 1 NADH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-7218, photosynthetic 3-hydroxybutanoate biosynthesis (engineered): PWY-7218
    • 7 reactions found over 10 reactions in the full pathway
  • PWY-7384, anaerobic energy metabolism (invertebrates, mitochondrial): PWY-7384
    • 6 reactions found over 12 reactions in the full pathway
  • PWY-6886, 1-butanol autotrophic biosynthesis (engineered): PWY-6886
    • 8 reactions found over 11 reactions in the full pathway
  • PWY-5537, pyruvate fermentation to acetate V: PWY-5537
    • 2 reactions found over 4 reactions in the full pathway
  • GLYCOLYSIS-TCA-GLYOX-BYPASS, superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass: GLYCOLYSIS-TCA-GLYOX-BYPASS
    • 3 reactions found over 5 reactions in the full pathway
  • PWY-5482, pyruvate fermentation to acetate II: PWY-5482
    • 1 reactions found over 3 reactions in the full pathway

Reconstruction information

External links