Difference between revisions of "L-LACTATE-DEHYDROGENASE-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=DCMP DCMP] == * smiles: ** C(C2(C(CC(N1(C(N=C(C=C1)N)=O))O2)O))OP([O-])([O-])=O * inchi key: **...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=L-LACTATE-DEHYDROGENASE-RXN L-LACTATE-DEHYDROGENASE-RXN] == * direction: ** REVERSIBLE * common nam...")
 
(2 intermediate revisions by the same user not shown)
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[[Category:Metabolite]]
+
[[Category:Reaction]]
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=DCMP DCMP] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=L-LACTATE-DEHYDROGENASE-RXN L-LACTATE-DEHYDROGENASE-RXN] ==
* smiles:
+
* direction:
** C(C2(C(CC(N1(C(N=C(C=C1)N)=O))O2)O))OP([O-])([O-])=O
+
** REVERSIBLE
* inchi key:
+
** InChIKey=NCMVOABPESMRCP-SHYZEUOFSA-L
+
 
* common name:
 
* common name:
** dCMP
+
** L-lactate dehydrogenase
* molecular weight:
+
* ec number:
** 305.183   
+
** [http://enzyme.expasy.org/EC/1.1.1.27 EC-1.1.1.27]
 
* Synonym(s):
 
* Synonym(s):
** 2'-deoxycytidine 5'-monophosphate
 
** deoxycytidylate
 
** deoxycytidylic acid
 
** deoxycytidine monophosphate
 
** 2'-deoxycytidine 5'-phosphate
 
** deoxycytidine-phosphate
 
  
== Reaction(s) known to consume the compound ==
+
== Reaction Formula ==
* [[RXN-7913]]
+
* With identifiers:
* [[DCMP-DEAMINASE-RXN]]
+
** 1 [[L-LACTATE]][c] '''+''' 1 [[NAD]][c] '''<=>''' 1 [[NADH]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[PYRUVATE]][c]
== Reaction(s) known to produce the compound ==
+
* With common name(s):
* [[RXN-14187]]
+
** 1 (S)-lactate[c] '''+''' 1 NAD+[c] '''<=>''' 1 NADH[c] '''+''' 1 H+[c] '''+''' 1 pyruvate[c]
* [[RXN-14198]]
+
 
== Reaction(s) of unknown directionality ==
+
== Genes associated with this reaction  ==
 +
Genes have been associated with this reaction based on different elements listed below.
 +
* Gene: [[Ec-12_006780]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: GO-TERM
 +
== Pathways  ==
 +
* [[P122-PWY]], heterolactic fermentation: [http://metacyc.org/META/NEW-IMAGE?object=P122-PWY P122-PWY]
 +
** '''13''' reactions found over '''18''' reactions in the full pathway
 +
* [[PWY-5481]], pyruvate fermentation to lactate: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5481 PWY-5481]
 +
** '''1''' reactions found over '''1''' reactions in the full pathway
 +
* [[P124-PWY]], Bifidobacterium shunt: [http://metacyc.org/META/NEW-IMAGE?object=P124-PWY P124-PWY]
 +
** '''12''' reactions found over '''15''' reactions in the full pathway
 +
* [[PWY-6901]], superpathway of glucose and xylose degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6901 PWY-6901]
 +
** '''9''' reactions found over '''12''' reactions in the full pathway
 +
== Reconstruction information  ==
 +
* Category: [[annotation]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
* CAS : 1032-65-1
+
* RHEA:
* BIGG : 34352
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=23444 23444]
* PUBCHEM:
+
* LIGAND-RXN:
** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=7058169 7058169]
+
** [http://www.genome.jp/dbget-bin/www_bget?R00703 R00703]
* HMDB : HMDB01202
+
* UNIPROT:
* LIGAND-CPD:
+
** [http://www.uniprot.org/uniprot/P04034 P04034]
** [http://www.genome.jp/dbget-bin/www_bget?C00239 C00239]
+
** [http://www.uniprot.org/uniprot/P04642 P04642]
* CHEMSPIDER:
+
** [http://www.uniprot.org/uniprot/P06150 P06150]
** [http://www.chemspider.com/Chemical-Structure.5414501.html 5414501]
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** [http://www.uniprot.org/uniprot/P20373 P20373]
* CHEBI:
+
** [http://www.uniprot.org/uniprot/P13491 P13491]
** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57566 57566]
+
** [http://www.uniprot.org/uniprot/P22988 P22988]
* METABOLIGHTS : MTBLC57566
+
** [http://www.uniprot.org/uniprot/P56512 P56512]
{{#set: smiles=C(C2(C(CC(N1(C(N=C(C=C1)N)=O))O2)O))OP([O-])([O-])=O}}
+
** [http://www.uniprot.org/uniprot/Q7M1E1 Q7M1E1]
{{#set: inchi key=InChIKey=NCMVOABPESMRCP-SHYZEUOFSA-L}}
+
** [http://www.uniprot.org/uniprot/P33571 P33571]
{{#set: common name=dCMP}}
+
** [http://www.uniprot.org/uniprot/P13743 P13743]
{{#set: molecular weight=305.183    }}
+
** [http://www.uniprot.org/uniprot/P26283 P26283]
{{#set: common name=2'-deoxycytidine 5'-monophosphate|deoxycytidylate|deoxycytidylic acid|deoxycytidine monophosphate|2'-deoxycytidine 5'-phosphate|deoxycytidine-phosphate}}
+
** [http://www.uniprot.org/uniprot/Q01462 Q01462]
{{#set: consumed by=RXN-7913|DCMP-DEAMINASE-RXN}}
+
** [http://www.uniprot.org/uniprot/Q06176 Q06176]
{{#set: produced by=RXN-14187|RXN-14198}}
+
** [http://www.uniprot.org/uniprot/Q9PNC8 Q9PNC8]
 +
** [http://www.uniprot.org/uniprot/Q59244 Q59244]
 +
** [http://www.uniprot.org/uniprot/P13490 P13490]
 +
** [http://www.uniprot.org/uniprot/P22989 P22989]
 +
** [http://www.uniprot.org/uniprot/P56511 P56511]
 +
** [http://www.uniprot.org/uniprot/Q60176 Q60176]
 +
** [http://www.uniprot.org/uniprot/P33232 P33232]
 +
** [http://www.uniprot.org/uniprot/P00344 P00344]
 +
** [http://www.uniprot.org/uniprot/P00345 P00345]
 +
** [http://www.uniprot.org/uniprot/P00337 P00337]
 +
** [http://www.uniprot.org/uniprot/P00340 P00340]
 +
** [http://www.uniprot.org/uniprot/P00341 P00341]
 +
** [http://www.uniprot.org/uniprot/P07864 P07864]
 +
** [http://www.uniprot.org/uniprot/P07195 P07195]
 +
** [http://www.uniprot.org/uniprot/P00338 P00338]
 +
** [http://www.uniprot.org/uniprot/P00343 P00343]
 +
** [http://www.uniprot.org/uniprot/P00342 P00342]
 +
** [http://www.uniprot.org/uniprot/P06151 P06151]
 +
** [http://www.uniprot.org/uniprot/P00336 P00336]
 +
** [http://www.uniprot.org/uniprot/P00339 P00339]
 +
** [http://www.uniprot.org/uniprot/P13714 P13714]
 +
** [http://www.uniprot.org/uniprot/P50933 P50933]
 +
** [http://www.uniprot.org/uniprot/O23569 O23569]
 +
** [http://www.uniprot.org/uniprot/P47698 P47698]
 +
** [http://www.uniprot.org/uniprot/Q9CII4 Q9CII4]
 +
** [http://www.uniprot.org/uniprot/Q9CGG8 Q9CGG8]
 +
** [http://www.uniprot.org/uniprot/Q07251 Q07251]
 +
** [http://www.uniprot.org/uniprot/Q62545 Q62545]
 +
** [http://www.uniprot.org/uniprot/P42121 P42121]
 +
** [http://www.uniprot.org/uniprot/P42119 P42119]
 +
** [http://www.uniprot.org/uniprot/P42120 P42120]
 +
** [http://www.uniprot.org/uniprot/P42123 P42123]
 +
** [http://www.uniprot.org/uniprot/P19629 P19629]
 +
** [http://www.uniprot.org/uniprot/Q60009 Q60009]
 +
** [http://www.uniprot.org/uniprot/Q27888 Q27888]
 +
** [http://www.uniprot.org/uniprot/P19869 P19869]
 +
** [http://www.uniprot.org/uniprot/P19858 P19858]
 +
** [http://www.uniprot.org/uniprot/P13715 P13715]
 +
** [http://www.uniprot.org/uniprot/P10655 P10655]
 +
** [http://www.uniprot.org/uniprot/P14561 P14561]
 +
** [http://www.uniprot.org/uniprot/P20619 P20619]
 +
** [http://www.uniprot.org/uniprot/P16125 P16125]
 +
** [http://www.uniprot.org/uniprot/P29038 P29038]
 +
** [http://www.uniprot.org/uniprot/P0C0J3 P0C0J3]
 +
** [http://www.uniprot.org/uniprot/P16115 P16115]
 +
** [http://www.uniprot.org/uniprot/Q48662 Q48662]
 +
** [http://www.uniprot.org/uniprot/Q9ZRJ5 Q9ZRJ5]
 +
** [http://www.uniprot.org/uniprot/O81272 O81272]
 +
** [http://www.uniprot.org/uniprot/Q9SBE4 Q9SBE4]
 +
** [http://www.uniprot.org/uniprot/Q96569 Q96569]
 +
** [http://www.uniprot.org/uniprot/Q96570 Q96570]
 +
** [http://www.uniprot.org/uniprot/P46454 P46454]
 +
{{#set: direction=REVERSIBLE}}
 +
{{#set: common name=L-lactate dehydrogenase}}
 +
{{#set: ec number=EC-1.1.1.27}}
 +
{{#set: gene associated=Ec-12_006780}}
 +
{{#set: in pathway=P122-PWY|PWY-5481|P124-PWY|PWY-6901}}
 +
{{#set: reconstruction category=annotation}}
 +
{{#set: reconstruction source=annotation-esiliculosus_genome}}
 +
{{#set: reconstruction tool=pathwaytools}}

Latest revision as of 19:35, 21 March 2018

Reaction L-LACTATE-DEHYDROGENASE-RXN

  • direction:
    • REVERSIBLE
  • common name:
    • L-lactate dehydrogenase
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 (S)-lactate[c] + 1 NAD+[c] <=> 1 NADH[c] + 1 H+[c] + 1 pyruvate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • P122-PWY, heterolactic fermentation: P122-PWY
    • 13 reactions found over 18 reactions in the full pathway
  • PWY-5481, pyruvate fermentation to lactate: PWY-5481
    • 1 reactions found over 1 reactions in the full pathway
  • P124-PWY, Bifidobacterium shunt: P124-PWY
    • 12 reactions found over 15 reactions in the full pathway
  • PWY-6901, superpathway of glucose and xylose degradation: PWY-6901
    • 9 reactions found over 12 reactions in the full pathway

Reconstruction information

External links