Difference between revisions of "HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-9533 RXN-9533] == * direction: ** LEFT-TO-RIGHT * ec number: ** [http://enzyme.expasy.org/EC/2....")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN] == * direction: ** LEFT-TO...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-9533 RXN-9533] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN] ==
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
 +
* common name:
 +
** Hydroxymethylglutaryl-CoA lyase
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/2.3.1.86 EC-2.3.1.86]
+
** [http://enzyme.expasy.org/EC/4.1.3.4 EC-4.1.3.4]
−
** [http://enzyme.expasy.org/EC/2.3.1.85 EC-2.3.1.85]
+
−
** [http://enzyme.expasy.org/EC/4.2.1.59 EC-4.2.1.59]
+
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[R-3-hydroxydodecanoyl-ACPs]][c] '''=>''' 1 [[Dodec-2-enoyl-ACPs]][c] '''+''' 1 [[WATER]][c]
+
** 1 [[3-HYDROXY-3-METHYL-GLUTARYL-COA]][c] '''=>''' 1 [[ACETYL-COA]][c] '''+''' 1 [[3-KETOBUTYRATE]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 a (3R)-3-hydroxydodecanoyl-[acp][c] '''=>''' 1 a (2E)-dodec-2-enoyl-[acp][c] '''+''' 1 H2O[c]
+
** 1 (S)-3-hydroxy-3-methylglutaryl-CoA[c] '''=>''' 1 acetyl-CoA[c] '''+''' 1 acetoacetate[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 +
Genes have been associated with this reaction based on different elements listed below.
 +
* Gene: [[Ec-26_006120]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[orthology-aragem]]
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-5994]], palmitate biosynthesis I (animals and fungi): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5994 PWY-5994]
+
* [[PWY66-367]], ketogenesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY66-367 PWY66-367]
−
** '''20''' reactions found over '''31''' reactions in the full pathway
+
** '''3''' reactions found over '''5''' reactions in the full pathway
−
* [[PWY-5971]], palmitate biosynthesis II (bacteria and plants): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5971 PWY-5971]
+
* [[LEU-DEG2-PWY]], L-leucine degradation I: [http://metacyc.org/META/NEW-IMAGE?object=LEU-DEG2-PWY LEU-DEG2-PWY]
−
** '''28''' reactions found over '''31''' reactions in the full pathway
+
** '''6''' reactions found over '''6''' reactions in the full pathway
−
* [[PWY-7664]], oleate biosynthesis IV (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7664 PWY-7664]
+
* [[PWY-5074]], mevalonate degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5074 PWY-5074]
−
** '''10''' reactions found over '''14''' reactions in the full pathway
+
** '''1''' reactions found over '''2''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
−
* [[gap-filling]]:
+
* Category: [[orthology]]
−
** [[meneco]]:
+
** Source: [[orthology-aragem]]
−
*** [[added for gapfilling]]
+
*** Tool: [[pantograph]]
 +
* Category: [[annotation]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
 +
* RHEA:
 +
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=24404 24404]
 +
* LIGAND-RXN:
 +
** [http://www.genome.jp/dbget-bin/www_bget?R01360 R01360]
 +
* UNIPROT:
 +
** [http://www.uniprot.org/uniprot/P35914 P35914]
 +
** [http://www.uniprot.org/uniprot/P35915 P35915]
 +
** [http://www.uniprot.org/uniprot/Q8L7K2 Q8L7K2]
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
−
{{#set: ec number=EC-2.3.1.86}}
+
{{#set: common name=Hydroxymethylglutaryl-CoA lyase}}
−
{{#set: ec number=EC-2.3.1.85}}
+
{{#set: ec number=EC-4.1.3.4}}
−
{{#set: ec number=EC-4.2.1.59}}
+
{{#set: gene associated=Ec-26_006120}}
−
{{#set: in pathway=PWY-5994|PWY-5971|PWY-7664}}
+
{{#set: in pathway=PWY66-367|LEU-DEG2-PWY|PWY-5074}}
−
{{#set: reconstruction category=gap-filling}}
+
{{#set: reconstruction category=orthology|annotation}}
−
{{#set: reconstruction tool=meneco}}
+
{{#set: reconstruction source=annotation-esiliculosus_genome|orthology-aragem}}
−
{{#set: reconstruction source=added for gapfilling}}
+
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 20:43, 21 March 2018

Reaction HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • Hydroxymethylglutaryl-CoA lyase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY66-367, ketogenesis: PWY66-367
    • 3 reactions found over 5 reactions in the full pathway
  • LEU-DEG2-PWY, L-leucine degradation I: LEU-DEG2-PWY
    • 6 reactions found over 6 reactions in the full pathway
  • PWY-5074, mevalonate degradation: PWY-5074
    • 1 reactions found over 2 reactions in the full pathway

Reconstruction information

External links





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