Difference between revisions of "NUCLEOSIDE-DIPHOSPHATASE-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=HISTIDINOL HISTIDINOL] == * smiles: ** C1(NC=NC=1CC(CO)[N+]) * inchi key: ** InChIKey=ZQISRDCJN...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=METHYLENETHFDEHYDROG-NADP-RXN METHYLENETHFDEHYDROG-NADP-RXN] == * direction: ** REVERSIBLE * common...")
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=HISTIDINOL HISTIDINOL] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=METHYLENETHFDEHYDROG-NADP-RXN METHYLENETHFDEHYDROG-NADP-RXN] ==
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* smiles:
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* direction:
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** C1(NC=NC=1CC(CO)[N+])
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** REVERSIBLE
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* inchi key:
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** InChIKey=ZQISRDCJNBUVMM-YFKPBYRVSA-O
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* common name:
 
* common name:
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** histidinol
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** methylenetetrahydrofolate dehydrogenase (NADP+)
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* molecular weight:
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* ec number:
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** 142.18   
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** [http://enzyme.expasy.org/EC/1.5.1.5 EC-1.5.1.5]
 
* Synonym(s):
 
* Synonym(s):
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** histidol
 
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** L-histidinol
 
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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* [[RXN-8001]]
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* With identifiers:
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== Reaction(s) known to produce the compound ==
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** 1 [[METHYLENE-THF-GLU-N]][c] '''+''' 1 [[NADP]][c] '''<=>''' 1 [[5-10-METHENYL-THF-GLU-N]][c] '''+''' 1 [[NADPH]][c]
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* [[HISTIDPHOS-RXN]]
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* With common name(s):
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* [[HISTIDPHOS-RXN[CCO-CYTOSOL]-L-HISTIDINOL-P/WATER//HISTIDINOL/Pi.49.]]
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** 1 a 5,10-methylene-tetrahydrofolate[c] '''+''' 1 NADP+[c] '''<=>''' 1 a 5,10-methenyltetrahydrofolate[c] '''+''' 1 NADPH[c]
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== Reaction(s) of unknown directionality ==
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* [[HISTOLDEHYD-RXN]]
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[Ec-15_001370]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Assignment: GO-TERM
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* Gene: [[Ec-14_004070]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Assignment: GO-TERM
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* Gene: [[Ec-07_007470]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Assignment: GO-TERM
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== Pathways  ==
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* [[PWY-1722]], formate assimilation into 5,10-methylenetetrahydrofolate: [http://metacyc.org/META/NEW-IMAGE?object=PWY-1722 PWY-1722]
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** '''3''' reactions found over '''3''' reactions in the full pathway
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* [[PWY-3841]], folate transformations II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-3841 PWY-3841]
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** '''10''' reactions found over '''11''' reactions in the full pathway
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* [[1CMET2-PWY]], N10-formyl-tetrahydrofolate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=1CMET2-PWY 1CMET2-PWY]
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** '''9''' reactions found over '''9''' reactions in the full pathway
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* [[CODH-PWY]], reductive acetyl coenzyme A pathway I (homoacetogenic bacteria): [http://metacyc.org/META/NEW-IMAGE?object=CODH-PWY CODH-PWY]
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** '''5''' reactions found over '''9''' reactions in the full pathway
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* [[PWY-5497]], purine nucleobases degradation II (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5497 PWY-5497]
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** '''8''' reactions found over '''24''' reactions in the full pathway
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* [[PWY-2201]], folate transformations I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-2201 PWY-2201]
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** '''12''' reactions found over '''12''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[annotation]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* CAS : 501-28-0
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* RHEA:
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* PUBCHEM:
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=22812 22812]
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=6950298 6950298]
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* LIGAND-RXN:
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* KNAPSACK : C00007479
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** [http://www.genome.jp/dbget-bin/www_bget?R01220 R01220]
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* HMDB : HMDB03431
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* UNIPROT:
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* LIGAND-CPD:
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** [http://www.uniprot.org/uniprot/P09440 P09440]
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** [http://www.genome.jp/dbget-bin/www_bget?C00860 C00860]
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** [http://www.uniprot.org/uniprot/P07245 P07245]
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* CHEBI:
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** [http://www.uniprot.org/uniprot/P11586 P11586]
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57699 57699]
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** [http://www.uniprot.org/uniprot/P44313 P44313]
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* BIGG : 36226
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** [http://www.uniprot.org/uniprot/P47259 P47259]
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{{#set: smiles=C1(NC=NC=1CC(CO)[N+])}}
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** [http://www.uniprot.org/uniprot/P54382 P54382]
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{{#set: inchi key=InChIKey=ZQISRDCJNBUVMM-YFKPBYRVSA-O}}
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** [http://www.uniprot.org/uniprot/O67736 O67736]
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{{#set: common name=histidinol}}
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** [http://www.uniprot.org/uniprot/Q9JWI9 Q9JWI9]
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{{#set: molecular weight=142.18    }}
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** [http://www.uniprot.org/uniprot/Q9PP68 Q9PP68]
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{{#set: common name=histidol|L-histidinol}}
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** [http://www.uniprot.org/uniprot/P24186 P24186]
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{{#set: consumed by=RXN-8001}}
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** [http://www.uniprot.org/uniprot/Q60006 Q60006]
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{{#set: produced by=HISTIDPHOS-RXN|HISTIDPHOS-RXN[CCO-CYTOSOL]-L-HISTIDINOL-P/WATER//HISTIDINOL/Pi.49.}}
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** [http://www.uniprot.org/uniprot/Q27772 Q27772]
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{{#set: reversible reaction associated=HISTOLDEHYD-RXN}}
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** [http://www.uniprot.org/uniprot/P51696 P51696]
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** [http://www.uniprot.org/uniprot/O65269 O65269]
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** [http://www.uniprot.org/uniprot/O65271 O65271]
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** [http://www.uniprot.org/uniprot/O68031 O68031]
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** [http://www.uniprot.org/uniprot/Q9ZTV0 Q9ZTV0]
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** [http://www.uniprot.org/uniprot/Q9X7F6 Q9X7F6]
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{{#set: direction=REVERSIBLE}}
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{{#set: common name=methylenetetrahydrofolate dehydrogenase (NADP+)}}
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{{#set: ec number=EC-1.5.1.5}}
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{{#set: gene associated=Ec-15_001370|Ec-14_004070|Ec-07_007470}}
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{{#set: in pathway=PWY-1722|PWY-3841|1CMET2-PWY|CODH-PWY|PWY-5497|PWY-2201}}
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{{#set: reconstruction category=annotation}}
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{{#set: reconstruction source=annotation-esiliculosus_genome}}
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{{#set: reconstruction tool=pathwaytools}}

Revision as of 13:31, 21 March 2018

Reaction METHYLENETHFDEHYDROG-NADP-RXN

  • direction:
    • REVERSIBLE
  • common name:
    • methylenetetrahydrofolate dehydrogenase (NADP+)
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-1722, formate assimilation into 5,10-methylenetetrahydrofolate: PWY-1722
    • 3 reactions found over 3 reactions in the full pathway
  • PWY-3841, folate transformations II: PWY-3841
    • 10 reactions found over 11 reactions in the full pathway
  • 1CMET2-PWY, N10-formyl-tetrahydrofolate biosynthesis: 1CMET2-PWY
    • 9 reactions found over 9 reactions in the full pathway
  • CODH-PWY, reductive acetyl coenzyme A pathway I (homoacetogenic bacteria): CODH-PWY
    • 5 reactions found over 9 reactions in the full pathway
  • PWY-5497, purine nucleobases degradation II (anaerobic): PWY-5497
    • 8 reactions found over 24 reactions in the full pathway
  • PWY-2201, folate transformations I: PWY-2201
    • 12 reactions found over 12 reactions in the full pathway

Reconstruction information

External links





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