Difference between revisions of "2OXOGLUTDECARB-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD-8620 CPD-8620] == * smiles: ** CC(C)CCCC([CH]4(C1(C)([CH](C2(=C(CC1)C3(C)([CH](CC2)CC(=O)CC...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=2OXOGLUTDECARB-RXN 2OXOGLUTDECARB-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** dihydroli...")
 
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD-8620 CPD-8620] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=2OXOGLUTDECARB-RXN 2OXOGLUTDECARB-RXN] ==
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* smiles:
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* direction:
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** CC(C)CCCC([CH]4(C1(C)([CH](C2(=C(CC1)C3(C)([CH](CC2)CC(=O)CC3)))CC4)))C
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** LEFT-TO-RIGHT
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* inchi key:
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** InChIKey=RZSXSHNNQBIPTL-ZSBATXSLSA-N
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* common name:
 
* common name:
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** 5α-cholesta-8-en-3-one
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** dihydrolipoamide dehydrogenase
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* molecular weight:
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** Oxoglutarate dehydrogenase, N-terminal part
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** 384.644   
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** 2-oxoglutarate dehydrogenase E1 component
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* ec number:
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** [http://enzyme.expasy.org/EC/1.2.4.2 EC-1.2.4.2]
 
* Synonym(s):
 
* Synonym(s):
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** Oxoglutarate decarboxylase
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** 2-oxoglutarate decarboxylation
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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== Reaction(s) known to produce the compound ==
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* With identifiers:
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* [[RXN66-23]]
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** 1 [[2-KETOGLUTARATE]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[Oxo-glutarate-dehydrogenase-lipoyl]][c] '''=>''' 1 [[CARBON-DIOXIDE]][c] '''+''' 1 [[Oxo-glutarate-dehydro-suc-DH-lipoyl]][c]
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== Reaction(s) of unknown directionality ==
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* With common name(s):
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** 1 2-oxoglutarate[c] '''+''' 1 H+[c] '''+''' 1 a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] '''=>''' 1 CO2[c] '''+''' 1 a [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine[c]
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[Ec-25_000020]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Assignment: AUTOMATED-NAME-MATCH
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* Gene: [[Ec-21_002310]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Assignment: EC-NUMBER
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* Gene: [[Ec-21_002300]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Assignment: EC-NUMBER
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* Gene: [[Ec-27_004160]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Assignment: AUTOMATED-NAME-MATCH
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== Pathways  ==
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* [[PWY-5084]], 2-oxoglutarate decarboxylation to succinyl-CoA: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5084 PWY-5084]
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** '''3''' reactions found over '''3''' reactions in the full pathway
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* [[PWY66-398]], TCA cycle III (animals): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-398 PWY66-398]
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** '''10''' reactions found over '''11''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[annotation]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* PUBCHEM:
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* UNIPROT:
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=25203379 25203379]
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** [http://www.uniprot.org/uniprot/P23129 P23129]
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* HMDB : HMDB12178
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** [http://www.uniprot.org/uniprot/Q02218 Q02218]
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{{#set: smiles=CC(C)CCCC([CH]4(C1(C)([CH](C2(=C(CC1)C3(C)([CH](CC2)CC(=O)CC3)))CC4)))C}}
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** [http://www.uniprot.org/uniprot/Q60597 Q60597]
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{{#set: inchi key=InChIKey=RZSXSHNNQBIPTL-ZSBATXSLSA-N}}
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** [http://www.uniprot.org/uniprot/Q9JRJ8 Q9JRJ8]
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{{#set: common name=5α-cholesta-8-en-3-one}}
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** [http://www.uniprot.org/uniprot/P20967 P20967]
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{{#set: molecular weight=384.644    }}
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** [http://www.uniprot.org/uniprot/P0AFG3 P0AFG3]
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{{#set: produced by=RXN66-23}}
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** [http://www.uniprot.org/uniprot/P20707 P20707]
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** [http://www.uniprot.org/uniprot/P51056 P51056]
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** [http://www.uniprot.org/uniprot/Q56600 Q56600]
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** [http://www.uniprot.org/uniprot/O49541 O49541]
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** [http://www.uniprot.org/uniprot/Q59106 Q59106]
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** [http://www.uniprot.org/uniprot/Q9M2T8 Q9M2T8]
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** [http://www.uniprot.org/uniprot/Q9ZRQ2 Q9ZRQ2]
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{{#set: direction=LEFT-TO-RIGHT}}
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{{#set: common name=dihydrolipoamide dehydrogenase}}
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{{#set: common name=Oxoglutarate dehydrogenase, N-terminal part}}
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{{#set: common name=2-oxoglutarate dehydrogenase E1 component}}
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{{#set: ec number=EC-1.2.4.2}}
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{{#set: common name=Oxoglutarate decarboxylase|2-oxoglutarate decarboxylation}}
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{{#set: gene associated=Ec-25_000020|Ec-21_002310|Ec-21_002300|Ec-27_004160}}
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{{#set: in pathway=PWY-5084|PWY66-398}}
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{{#set: reconstruction category=annotation}}
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{{#set: reconstruction source=annotation-esiliculosus_genome}}
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{{#set: reconstruction tool=pathwaytools}}

Latest revision as of 19:36, 21 March 2018

Reaction 2OXOGLUTDECARB-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • dihydrolipoamide dehydrogenase
    • Oxoglutarate dehydrogenase, N-terminal part
    • 2-oxoglutarate dehydrogenase E1 component
  • ec number:
  • Synonym(s):
    • Oxoglutarate decarboxylase
    • 2-oxoglutarate decarboxylation

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-5084, 2-oxoglutarate decarboxylation to succinyl-CoA: PWY-5084
    • 3 reactions found over 3 reactions in the full pathway
  • PWY66-398, TCA cycle III (animals): PWY66-398
    • 10 reactions found over 11 reactions in the full pathway

Reconstruction information

External links






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