Difference between revisions of "GSHTRAN-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=UDPREDUCT-RXN UDPREDUCT-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** Ribonucleoside-diph...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=GSHTRAN-RXN GSHTRAN-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** Thioredoxin-like fold *...")
 
Line 1: Line 1:
 
[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=UDPREDUCT-RXN UDPREDUCT-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=GSHTRAN-RXN GSHTRAN-RXN] ==
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
−
** Ribonucleoside-diphosphate reductase small chain
+
** Thioredoxin-like fold
−
** ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
+
** Glutathione S-transferase, N-terminal
−
** EsV-1-128
+
** Glutathione S-transferase, C-terminal-like
−
** EsV-1-180
+
** Membrane associated eicosanoid/glutathione metabolism-like domain
 +
** Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein
 +
** DSBA-like thioredoxin domain
 +
** Glutathione S-transferase (GST)
 +
** putative Glutathione S-transferase
 +
** Glutathione S-transferase
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/1.17.4.1 EC-1.17.4.1]
+
** [http://enzyme.expasy.org/EC/2.5.1.18 EC-2.5.1.18]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[UDP]][c] '''+''' 1 [[Red-Thioredoxin]][c] '''=>''' 1 [[Ox-Thioredoxin]][c] '''+''' 1 [[DUDP]][c] '''+''' 1 [[WATER]][c]
+
** 1 [[GLUTATHIONE]][c] '''+''' 1 [[RX]][c] '''=>''' 1 [[HX]][c] '''+''' 1 [[S-Substituted-Glutathione]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 UDP[c] '''+''' 1 a reduced thioredoxin[c] '''=>''' 1 an oxidized thioredoxin[c] '''+''' 1 dUDP[c] '''+''' 1 H2O[c]
+
** 1 glutathione[c] '''+''' 1 RX[c] '''=>''' 1 HX[c] '''+''' 1 a glutathione-toxin conjugate[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* Gene: [[Ec-06_005120]]
+
* Gene: [[Ec-00_000320]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Ec-27_000390]]
 
** Source: [[annotation-esiliculosus_genome]]
 
** Source: [[annotation-esiliculosus_genome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
 
** Source: [[orthology-aragem]]
 
** Source: [[orthology-aragem]]
−
* Gene: [[Ec-21_002920]]
+
* Gene: [[Ec-20_001950]]
 
** Source: [[annotation-esiliculosus_genome]]
 
** Source: [[annotation-esiliculosus_genome]]
−
*** Assignment: GO-TERM
+
*** Assignment: AUTOMATED-NAME-MATCH
 +
* Gene: [[Ec-00_008380]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Ec-00_008370]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Ec-09_003670]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Ec-13_002370]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Ec-24_001030]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: AUTOMATED-NAME-MATCH
 +
* Gene: [[Ec-13_000340]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Ec-06_002520]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Ec-00_008890]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Ec-16_001680]]
 
** Source: [[orthology-aragem]]
 
** Source: [[orthology-aragem]]
−
* Gene: [[Ec-06_005570]]
+
* Gene: [[Ec-27_000400]]
 
** Source: [[annotation-esiliculosus_genome]]
 
** Source: [[annotation-esiliculosus_genome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
−
* Gene: [[Ec-11_002180]]
 
 
** Source: [[orthology-aragem]]
 
** Source: [[orthology-aragem]]
−
* Gene: [[Ec-17_003700]]
+
* Gene: [[Ec-00_008360]]
−
** Source: [[orthology-aragem]]
+
−
* Gene: [[Ec-11_002170]]
+
 
** Source: [[annotation-esiliculosus_genome]]
 
** Source: [[annotation-esiliculosus_genome]]
−
*** Assignment: GO-TERM
+
*** Assignment: EC-NUMBER
−
* Gene: [[Ec-19_000440]]
+
* Gene: [[Ec-06_008030]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Ec-18_001510]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Ec-13_002360]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Ec-00_008870]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Ec-11_002590]]
 
** Source: [[annotation-esiliculosus_genome]]
 
** Source: [[annotation-esiliculosus_genome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
 +
* Gene: [[Ec-10_001330]]
 
** Source: [[orthology-aragem]]
 
** Source: [[orthology-aragem]]
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-7184]], pyrimidine deoxyribonucleotides de novo biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7184 PWY-7184]
+
* [[PWY-6842]], glutathione-mediated detoxification II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6842 PWY-6842]
−
** '''9''' reactions found over '''9''' reactions in the full pathway
+
** '''2''' reactions found over '''8''' reactions in the full pathway
−
* [[PWY-6545]], pyrimidine deoxyribonucleotides de novo biosynthesis III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6545 PWY-6545]
+
* [[PWY-4061]], glutathione-mediated detoxification I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-4061 PWY-4061]
−
** '''8''' reactions found over '''9''' reactions in the full pathway
+
** '''2''' reactions found over '''5''' reactions in the full pathway
−
* [[PWY0-166]], superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli): [http://metacyc.org/META/NEW-IMAGE?object=PWY0-166 PWY0-166]
+
−
** '''14''' reactions found over '''17''' reactions in the full pathway
+
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[orthology]]
 
* Category: [[orthology]]
Line 57: Line 98:
 
*** Tool: [[pathwaytools]]
 
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
−
* RHEA:
 
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=28026 28026]
 
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R02018 R02018]
+
** [http://www.genome.jp/dbget-bin/www_bget?R03522 R03522]
 +
* UNIPROT:
 +
** [http://www.uniprot.org/uniprot/P30116 P30116]
 +
** [http://www.uniprot.org/uniprot/P04903 P04903]
 +
** [http://www.uniprot.org/uniprot/P04904 P04904]
 +
** [http://www.uniprot.org/uniprot/P13745 P13745]
 +
** [http://www.uniprot.org/uniprot/P08011 P08011]
 +
** [http://www.uniprot.org/uniprot/Q7M0B7 Q7M0B7]
 +
** [http://www.uniprot.org/uniprot/P08009 P08009]
 +
** [http://www.uniprot.org/uniprot/P04905 P04905]
 +
** [http://www.uniprot.org/uniprot/P21266 P21266]
 +
** [http://www.uniprot.org/uniprot/P09211 P09211]
 +
** [http://www.uniprot.org/uniprot/P28161 P28161]
 +
** [http://www.uniprot.org/uniprot/Q08863 Q08863]
 +
** [http://www.uniprot.org/uniprot/P30109 P30109]
 +
** [http://www.uniprot.org/uniprot/P28338 P28338]
 +
** [http://www.uniprot.org/uniprot/P46088 P46088]
 +
** [http://www.uniprot.org/uniprot/P15964 P15964]
 +
** [http://www.uniprot.org/uniprot/P46439 P46439]
 +
** [http://www.uniprot.org/uniprot/Q9VG97 Q9VG97]
 +
** [http://www.uniprot.org/uniprot/Q03013 Q03013]
 +
** [http://www.uniprot.org/uniprot/P41043 P41043]
 +
** [http://www.uniprot.org/uniprot/P28801 P28801]
 +
** [http://www.uniprot.org/uniprot/P46418 P46418]
 +
** [http://www.uniprot.org/uniprot/P46425 P46425]
 +
** [http://www.uniprot.org/uniprot/P0A9D2 P0A9D2]
 +
** [http://www.uniprot.org/uniprot/P08263 P08263]
 +
** [http://www.uniprot.org/uniprot/P30712 P30712]
 +
** [http://www.uniprot.org/uniprot/Q9NAW7 Q9NAW7]
 +
** [http://www.uniprot.org/uniprot/P08515 P08515]
 +
** [http://www.uniprot.org/uniprot/P10620 P10620]
 +
** [http://www.uniprot.org/uniprot/P19639 P19639]
 +
** [http://www.uniprot.org/uniprot/Q9WU21 Q9WU21]
 +
** [http://www.uniprot.org/uniprot/P15626 P15626]
 +
** [http://www.uniprot.org/uniprot/Q08862 Q08862]
 +
** [http://www.uniprot.org/uniprot/P26624 P26624]
 +
** [http://www.uniprot.org/uniprot/Q03377 Q03377]
 +
** [http://www.uniprot.org/uniprot/P19157 P19157]
 +
** [http://www.uniprot.org/uniprot/P20137 P20137]
 +
** [http://www.uniprot.org/uniprot/Q9VG95 Q9VG95]
 +
** [http://www.uniprot.org/uniprot/Q9VG98 Q9VG98]
 +
** [http://www.uniprot.org/uniprot/Q9VG96 Q9VG96]
 +
** [http://www.uniprot.org/uniprot/O31817 O31817]
 +
** [http://www.uniprot.org/uniprot/Q8X6U4 Q8X6U4]
 +
** [http://www.uniprot.org/uniprot/P30713 P30713]
 +
** [http://www.uniprot.org/uniprot/Q42706 Q42706]
 +
** [http://www.uniprot.org/uniprot/Q28514 Q28514]
 +
** [http://www.uniprot.org/uniprot/Q9TXB7 Q9TXB7]
 +
** [http://www.uniprot.org/uniprot/P09792 P09792]
 +
** [http://www.uniprot.org/uniprot/P16413 P16413]
 +
** [http://www.uniprot.org/uniprot/P81706 P81706]
 +
** [http://www.uniprot.org/uniprot/P09488 P09488]
 +
** [http://www.uniprot.org/uniprot/Q7M446 Q7M446]
 +
** [http://www.uniprot.org/uniprot/P10299 P10299]
 +
** [http://www.uniprot.org/uniprot/Q7M0B6 Q7M0B6]
 +
** [http://www.uniprot.org/uniprot/Q7M0C0 Q7M0C0]
 +
** [http://www.uniprot.org/uniprot/Q7M0F7 Q7M0F7]
 +
** [http://www.uniprot.org/uniprot/P22416 P22416]
 +
** [http://www.uniprot.org/uniprot/P30102 P30102]
 +
** [http://www.uniprot.org/uniprot/P28342 P28342]
 +
** [http://www.uniprot.org/uniprot/P24473 P24473]
 +
** [http://www.uniprot.org/uniprot/Q7M0F4 Q7M0F4]
 +
** [http://www.uniprot.org/uniprot/Q7M0F3 Q7M0F3]
 +
** [http://www.uniprot.org/uniprot/P26697 P26697]
 +
** [http://www.uniprot.org/uniprot/Q9PS57 Q9PS57]
 +
** [http://www.uniprot.org/uniprot/Q9JLQ6 Q9JLQ6]
 +
** [http://www.uniprot.org/uniprot/P30115 P30115]
 +
** [http://www.uniprot.org/uniprot/P09210 P09210]
 +
** [http://www.uniprot.org/uniprot/Q01579 Q01579]
 +
** [http://www.uniprot.org/uniprot/P24472 P24472]
 +
** [http://www.uniprot.org/uniprot/Q7M0F5 Q7M0F5]
 +
** [http://www.uniprot.org/uniprot/Q7M0F6 Q7M0F6]
 +
** [http://www.uniprot.org/uniprot/Q7M0F2 Q7M0F2]
 +
** [http://www.uniprot.org/uniprot/Q9TQQ8 Q9TQQ8]
 +
** [http://www.uniprot.org/uniprot/Q7M0B8 Q7M0B8]
 +
** [http://www.uniprot.org/uniprot/Q7M059 Q7M059]
 +
** [http://www.uniprot.org/uniprot/P30568 P30568]
 +
** [http://www.uniprot.org/uniprot/Q03425 Q03425]
 +
** [http://www.uniprot.org/uniprot/P10649 P10649]
 +
** [http://www.uniprot.org/uniprot/P46422 P46422]
 +
** [http://www.uniprot.org/uniprot/P45875 P45875]
 +
** [http://www.uniprot.org/uniprot/P42769 P42769]
 +
** [http://www.uniprot.org/uniprot/P46436 P46436]
 +
** [http://www.uniprot.org/uniprot/Q7M0F1 Q7M0F1]
 +
** [http://www.uniprot.org/uniprot/P42760 P42760]
 +
** [http://www.uniprot.org/uniprot/P42761 P42761]
 +
** [http://www.uniprot.org/uniprot/Q9GQE3 Q9GQE3]
 +
** [http://www.uniprot.org/uniprot/P46427 P46427]
 +
** [http://www.uniprot.org/uniprot/P48438 P48438]
 +
** [http://www.uniprot.org/uniprot/Q08392 Q08392]
 +
** [http://www.uniprot.org/uniprot/Q08393 Q08393]
 +
** [http://www.uniprot.org/uniprot/P30711 P30711]
 +
** [http://www.uniprot.org/uniprot/Q9UDH6 Q9UDH6]
 +
** [http://www.uniprot.org/uniprot/Q9UDH3 Q9UDH3]
 +
** [http://www.uniprot.org/uniprot/Q9UDH2 Q9UDH2]
 +
** [http://www.uniprot.org/uniprot/Q9UDH1 Q9UDH1]
 +
** [http://www.uniprot.org/uniprot/P46432 P46432]
 +
** [http://www.uniprot.org/uniprot/P46433 P46433]
 +
** [http://www.uniprot.org/uniprot/P46420 P46420]
 +
** [http://www.uniprot.org/uniprot/P27013 P27013]
 +
** [http://www.uniprot.org/uniprot/P27014 P27014]
 +
** [http://www.uniprot.org/uniprot/P20135 P20135]
 +
** [http://www.uniprot.org/uniprot/P46409 P46409]
 +
** [http://www.uniprot.org/uniprot/P46421 P46421]
 +
** [http://www.uniprot.org/uniprot/P46431 P46431]
 +
** [http://www.uniprot.org/uniprot/Q7M0B9 Q7M0B9]
 +
** [http://www.uniprot.org/uniprot/Q7M3E7 Q7M3E7]
 +
** [http://www.uniprot.org/uniprot/Q7M3E8 Q7M3E8]
 +
** [http://www.uniprot.org/uniprot/Q7M3E9 Q7M3E9]
 +
** [http://www.uniprot.org/uniprot/Q64471 Q64471]
 +
** [http://www.uniprot.org/uniprot/Q91VB0 Q91VB0]
 +
** [http://www.uniprot.org/uniprot/P15214 P15214]
 +
** [http://www.uniprot.org/uniprot/P47954 P47954]
 +
** [http://www.uniprot.org/uniprot/Q60550 Q60550]
 +
** [http://www.uniprot.org/uniprot/Q12760 Q12760]
 +
** [http://www.uniprot.org/uniprot/O65032 O65032]
 +
** [http://www.uniprot.org/uniprot/O65857 O65857]
 +
** [http://www.uniprot.org/uniprot/O82451 O82451]
 +
** [http://www.uniprot.org/uniprot/O24595 O24595]
 +
** [http://www.uniprot.org/uniprot/O49235 O49235]
 +
** [http://www.uniprot.org/uniprot/O04437 O04437]
 +
** [http://www.uniprot.org/uniprot/P30110 P30110]
 +
** [http://www.uniprot.org/uniprot/P30111 P30111]
 +
** [http://www.uniprot.org/uniprot/O04874 O04874]
 +
** [http://www.uniprot.org/uniprot/P32111 P32111]
 +
** [http://www.uniprot.org/uniprot/O22330 O22330]
 +
** [http://www.uniprot.org/uniprot/O49821 O49821]
 +
** [http://www.uniprot.org/uniprot/O65344 O65344]
 +
** [http://www.uniprot.org/uniprot/O81602 O81602]
 +
** [http://www.uniprot.org/uniprot/O85984 O85984]
 +
** [http://www.uniprot.org/uniprot/Q21355 Q21355]
 +
** [http://www.uniprot.org/uniprot/O16115 O16115]
 +
** [http://www.uniprot.org/uniprot/O16116 O16116]
 +
** [http://www.uniprot.org/uniprot/Q9ZRT5 Q9ZRT5]
 +
** [http://www.uniprot.org/uniprot/Q9ZRW8 Q9ZRW8]
 +
** [http://www.uniprot.org/uniprot/Q9SM20 Q9SM20]
 +
** [http://www.uniprot.org/uniprot/Q9ZP62 Q9ZP62]
 +
** [http://www.uniprot.org/uniprot/Q9ZS18 Q9ZS18]
 +
** [http://www.uniprot.org/uniprot/Q9ZS16 Q9ZS16]
 +
** [http://www.uniprot.org/uniprot/Q9SB97 Q9SB97]
 +
** [http://www.uniprot.org/uniprot/Q9ZS17 Q9ZS17]
 +
** [http://www.uniprot.org/uniprot/Q9ZRR6 Q9ZRR6]
 +
** [http://www.uniprot.org/uniprot/P20432 P20432]
 +
** [http://www.uniprot.org/uniprot/P14942 P14942]
 +
** [http://www.uniprot.org/uniprot/P08010 P08010]
 +
** [http://www.uniprot.org/uniprot/P04906 P04906]
 +
** [http://www.uniprot.org/uniprot/P12653 P12653]
 +
** [http://www.uniprot.org/uniprot/P04907 P04907]
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
−
{{#set: common name=Ribonucleoside-diphosphate reductase small chain}}
+
{{#set: common name=Thioredoxin-like fold}}
−
{{#set: common name=ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor}}
+
{{#set: common name=Glutathione S-transferase, N-terminal}}
−
{{#set: common name=EsV-1-128}}
+
{{#set: common name=Glutathione S-transferase, C-terminal-like}}
−
{{#set: common name=EsV-1-180}}
+
{{#set: common name=Membrane associated eicosanoid/glutathione metabolism-like domain}}
−
{{#set: ec number=EC-1.17.4.1}}
+
{{#set: common name=Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein}}
−
{{#set: gene associated=Ec-06_005120|Ec-21_002920|Ec-06_005570|Ec-11_002180|Ec-17_003700|Ec-11_002170|Ec-19_000440}}
+
{{#set: common name=DSBA-like thioredoxin domain}}
−
{{#set: in pathway=PWY-7184|PWY-6545|PWY0-166}}
+
{{#set: common name=Glutathione S-transferase (GST)}}
 +
{{#set: common name=putative Glutathione S-transferase}}
 +
{{#set: common name=Glutathione S-transferase}}
 +
{{#set: ec number=EC-2.5.1.18}}
 +
{{#set: gene associated=Ec-00_000320|Ec-27_000390|Ec-20_001950|Ec-00_008380|Ec-00_008370|Ec-09_003670|Ec-13_002370|Ec-24_001030|Ec-13_000340|Ec-06_002520|Ec-00_008890|Ec-16_001680|Ec-27_000400|Ec-00_008360|Ec-06_008030|Ec-18_001510|Ec-13_002360|Ec-00_008870|Ec-11_002590|Ec-10_001330}}
 +
{{#set: in pathway=PWY-6842|PWY-4061}}
 
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction source=annotation-esiliculosus_genome|orthology-aragem}}
 
{{#set: reconstruction source=annotation-esiliculosus_genome|orthology-aragem}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 19:36, 21 March 2018

Reaction GSHTRAN-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • Thioredoxin-like fold
    • Glutathione S-transferase, N-terminal
    • Glutathione S-transferase, C-terminal-like
    • Membrane associated eicosanoid/glutathione metabolism-like domain
    • Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein
    • DSBA-like thioredoxin domain
    • Glutathione S-transferase (GST)
    • putative Glutathione S-transferase
    • Glutathione S-transferase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6842, glutathione-mediated detoxification II: PWY-6842
    • 2 reactions found over 8 reactions in the full pathway
  • PWY-4061, glutathione-mediated detoxification I: PWY-4061
    • 2 reactions found over 5 reactions in the full pathway

Reconstruction information

External links









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