Difference between revisions of "RXN-13158"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=PYRUFLAVREDUCT-RXN PYRUFLAVREDUCT-RXN] == * direction: ** REVERSIBLE * common name: ** Transketolas...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-13158 RXN-13158] == * direction: ** LEFT-TO-RIGHT * common name: ** 3-isopropylmalate dehydroge...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=PYRUFLAVREDUCT-RXN PYRUFLAVREDUCT-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-13158 RXN-13158] ==
 
* direction:
 
* direction:
** REVERSIBLE
+
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
** Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II
+
** 3-isopropylmalate dehydrogenase
 
* ec number:
 
* ec number:
** [http://enzyme.expasy.org/EC/1.2.7.1 EC-1.2.7.1]
+
** [http://enzyme.expasy.org/EC/1.1.1.85 EC-1.1.1.85]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
** 1 [[CO-A]][c] '''+''' 1 [[PYRUVATE]][c] '''+''' 2 [[Oxidized-ferredoxins]][c] '''<=>''' 1 [[CARBON-DIOXIDE]][c] '''+''' 2 [[Reduced-ferredoxins]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[ACETYL-COA]][c]
+
** 1 [[2-D-THREO-HYDROXY-3-CARBOXY-ISOCAPROATE]][c] '''+''' 1 [[NAD]][c] '''=>''' 1 [[CARBON-DIOXIDE]][c] '''+''' 1 [[NADH]][c] '''+''' 1 [[2K-4CH3-PENTANOATE]][c]
 
* With common name(s):
 
* With common name(s):
** 1 coenzyme A[c] '''+''' 1 pyruvate[c] '''+''' 2 an oxidized ferredoxin [iron-sulfur] cluster[c] '''<=>''' 1 CO2[c] '''+''' 2 a reduced ferredoxin [iron-sulfur] cluster[c] '''+''' 1 H+[c] '''+''' 1 acetyl-CoA[c]
+
** 1 (2R,3S)-3-isopropylmalate[c] '''+''' 1 NAD+[c] '''=>''' 1 CO2[c] '''+''' 1 NADH[c] '''+''' 1 4-methyl-2-oxopentanoate[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
* Gene: [[Ec-18_003420]]
+
* Gene: [[Ec-16_002120]]
 
** Source: [[annotation-esiliculosus_genome]]
 
** Source: [[annotation-esiliculosus_genome]]
*** Assignment: AUTOMATED-NAME-MATCH
+
*** Assignment: EC-NUMBER
* Gene: [[Ec-15_004230]]
+
** Source: [[annotation-esiliculosus_genome]]
+
*** Assignment: AUTOMATED-NAME-MATCH
+
* Gene: [[Ec-23_002710]]
+
** Source: [[annotation-esiliculosus_genome]]
+
*** Assignment: AUTOMATED-NAME-MATCH
+
 
== Pathways  ==
 
== Pathways  ==
* [[PWY-6876]], isopropanol biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6876 PWY-6876]
 
** '''2''' reactions found over '''5''' reactions in the full pathway
 
* [[P23-PWY]], reductive TCA cycle I: [http://metacyc.org/META/NEW-IMAGE?object=P23-PWY P23-PWY]
 
** '''10''' reactions found over '''12''' reactions in the full pathway
 
* [[P42-PWY]], incomplete reductive TCA cycle: [http://metacyc.org/META/NEW-IMAGE?object=P42-PWY P42-PWY]
 
** '''5''' reactions found over '''7''' reactions in the full pathway
 
* [[PWY-6588]], pyruvate fermentation to acetone: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6588 PWY-6588]
 
** '''2''' reactions found over '''5''' reactions in the full pathway
 
* [[NPGLUCAT-PWY]], Entner-Doudoroff pathway II (non-phosphorylative): [http://metacyc.org/META/NEW-IMAGE?object=NPGLUCAT-PWY NPGLUCAT-PWY]
 
** '''4''' reactions found over '''9''' reactions in the full pathway
 
* [[CENTFERM-PWY]], pyruvate fermentation to butanoate: [http://metacyc.org/META/NEW-IMAGE?object=CENTFERM-PWY CENTFERM-PWY]
 
** '''4''' reactions found over '''7''' reactions in the full pathway
 
* [[PWY-5392]], reductive TCA cycle II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5392 PWY-5392]
 
** '''6''' reactions found over '''12''' reactions in the full pathway
 
* [[PWY-5483]], pyruvate fermentation to acetate III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5483 PWY-5483]
 
** '''1''' reactions found over '''4''' reactions in the full pathway
 
* [[PWY-6583]], pyruvate fermentation to butanol I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6583 PWY-6583]
 
** '''4''' reactions found over '''8''' reactions in the full pathway
 
* [[PWY-5493]], reductive monocarboxylic acid cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5493 PWY-5493]
 
** '''1''' reactions found over '''2''' reactions in the full pathway
 
* [[PWY-5600]], pyruvate fermentation to acetate VII: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5600 PWY-5600]
 
** '''1''' reactions found over '''3''' reactions in the full pathway
 
* [[PWY-6587]], pyruvate fermentation to ethanol III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6587 PWY-6587]
 
** '''1''' reactions found over '''3''' reactions in the full pathway
 
* [[PWY-5497]], purine nucleobases degradation II (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5497 PWY-5497]
 
** '''8''' reactions found over '''24''' reactions in the full pathway
 
* [[GLUDEG-II-PWY]], L-glutamate degradation VII (to butanoate): [http://metacyc.org/META/NEW-IMAGE?object=GLUDEG-II-PWY GLUDEG-II-PWY]
 
** '''3''' reactions found over '''6''' reactions in the full pathway
 
* [[PWY-6142]], gluconeogenesis II (Methanobacterium thermoautotrophicum): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6142 PWY-6142]
 
** '''10''' reactions found over '''14''' reactions in the full pathway
 
* [[PWY-5538]], pyruvate fermentation to acetate VI: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5538 PWY-5538]
 
** '''2''' reactions found over '''4''' reactions in the full pathway
 
* [[P142-PWY]], pyruvate fermentation to acetate I: [http://metacyc.org/META/NEW-IMAGE?object=P142-PWY P142-PWY]
 
** '''1''' reactions found over '''3''' reactions in the full pathway
 
* [[PWY-6863]], pyruvate fermentation to hexanol (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6863 PWY-6863]
 
** '''7''' reactions found over '''11''' reactions in the full pathway
 
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[annotation]]
 
* Category: [[annotation]]
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*** Tool: [[pathwaytools]]
 
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
* LIGAND-RXN:
+
* RHEA:
** [http://www.genome.jp/dbget-bin/www_bget?R01196 R01196]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=32272 32272]
* UNIPROT:
+
{{#set: direction=LEFT-TO-RIGHT}}
** [http://www.uniprot.org/uniprot/Q57957 Q57957]
+
{{#set: common name=3-isopropylmalate dehydrogenase}}
** [http://www.uniprot.org/uniprot/O28574 O28574]
+
{{#set: ec number=EC-1.1.1.85}}
** [http://www.uniprot.org/uniprot/Q56316 Q56316]
+
{{#set: gene associated=Ec-16_002120}}
** [http://www.uniprot.org/uniprot/Q9R503 Q9R503]
+
{{#set: in pathway=}}
** [http://www.uniprot.org/uniprot/Q57714 Q57714]
+
** [http://www.uniprot.org/uniprot/O05651 O05651]
+
** [http://www.uniprot.org/uniprot/Q57715 Q57715]
+
** [http://www.uniprot.org/uniprot/O27771 O27771]
+
** [http://www.uniprot.org/uniprot/O28572 O28572]
+
** [http://www.uniprot.org/uniprot/Q56317 Q56317]
+
** [http://www.uniprot.org/uniprot/Q9UWL2 Q9UWL2]
+
** [http://www.uniprot.org/uniprot/P56810 P56810]
+
** [http://www.uniprot.org/uniprot/O28571 O28571]
+
** [http://www.uniprot.org/uniprot/Q9UWL1 Q9UWL1]
+
** [http://www.uniprot.org/uniprot/Q57717 Q57717]
+
** [http://www.uniprot.org/uniprot/O25312 O25312]
+
** [http://www.uniprot.org/uniprot/O25738 O25738]
+
** [http://www.uniprot.org/uniprot/O25739 O25739]
+
** [http://www.uniprot.org/uniprot/O58411 O58411]
+
** [http://www.uniprot.org/uniprot/Q9UYZ4 Q9UYZ4]
+
** [http://www.uniprot.org/uniprot/Q9UYZ3 Q9UYZ3]
+
** [http://www.uniprot.org/uniprot/Q59455 Q59455]
+
** [http://www.uniprot.org/uniprot/Q59456 Q59456]
+
** [http://www.uniprot.org/uniprot/P80521 P80521]
+
** [http://www.uniprot.org/uniprot/P80522 P80522]
+
** [http://www.uniprot.org/uniprot/P80523 P80523]
+
** [http://www.uniprot.org/uniprot/P80524 P80524]
+
** [http://www.uniprot.org/uniprot/P95903 P95903]
+
** [http://www.uniprot.org/uniprot/P95904 P95904]
+
** [http://www.uniprot.org/uniprot/Q51799 Q51799]
+
** [http://www.uniprot.org/uniprot/Q51800 Q51800]
+
** [http://www.uniprot.org/uniprot/Q51802 Q51802]
+
** [http://www.uniprot.org/uniprot/Q51803 Q51803]
+
** [http://www.uniprot.org/uniprot/Q51804 Q51804]
+
** [http://www.uniprot.org/uniprot/Q51805 Q51805]
+
{{#set: direction=REVERSIBLE}}
+
{{#set: common name=Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II}}
+
{{#set: ec number=EC-1.2.7.1}}
+
{{#set: gene associated=Ec-18_003420|Ec-15_004230|Ec-23_002710}}
+
{{#set: in pathway=PWY-6876|P23-PWY|P42-PWY|PWY-6588|NPGLUCAT-PWY|CENTFERM-PWY|PWY-5392|PWY-5483|PWY-6583|PWY-5493|PWY-5600|PWY-6587|PWY-5497|GLUDEG-II-PWY|PWY-6142|PWY-5538|P142-PWY|PWY-6863}}
+
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction source=annotation-esiliculosus_genome}}
 
{{#set: reconstruction source=annotation-esiliculosus_genome}}
 
{{#set: reconstruction tool=pathwaytools}}
 
{{#set: reconstruction tool=pathwaytools}}

Latest revision as of 19:42, 21 March 2018

Reaction RXN-13158

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • 3-isopropylmalate dehydrogenase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

Reconstruction information

External links