Difference between revisions of "HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=ExchangeSeed_ZN+2 ExchangeSeed_ZN+2] == * direction: ** REVERSIBLE * Synonym(s): == Reaction Formu...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN] == * direction: ** LEFT-TO...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=ExchangeSeed_ZN+2 ExchangeSeed_ZN+2] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN] ==
 
* direction:
 
* direction:
−
** REVERSIBLE
+
** LEFT-TO-RIGHT
 +
* common name:
 +
** Hydroxymethylglutaryl-CoA lyase
 +
* ec number:
 +
** [http://enzyme.expasy.org/EC/4.1.3.4 EC-4.1.3.4]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1.0 [[ZN+2]][C-BOUNDARY] '''<=>''' 1.0 [[ZN+2]][e]
+
** 1 [[3-HYDROXY-3-METHYL-GLUTARYL-COA]][c] '''=>''' 1 [[ACETYL-COA]][c] '''+''' 1 [[3-KETOBUTYRATE]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1.0 Zn2+[C-BOUNDARY] '''<=>''' 1.0 Zn2+[e]
+
** 1 (S)-3-hydroxy-3-methylglutaryl-CoA[c] '''=>''' 1 acetyl-CoA[c] '''+''' 1 acetoacetate[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 +
Genes have been associated with this reaction based on different elements listed below.
 +
* Gene: [[Ec-26_006120]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[orthology-aragem]]
 
== Pathways  ==
 
== Pathways  ==
 +
* [[PWY66-367]], ketogenesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY66-367 PWY66-367]
 +
** '''3''' reactions found over '''5''' reactions in the full pathway
 +
* [[LEU-DEG2-PWY]], L-leucine degradation I: [http://metacyc.org/META/NEW-IMAGE?object=LEU-DEG2-PWY LEU-DEG2-PWY]
 +
** '''6''' reactions found over '''6''' reactions in the full pathway
 +
* [[PWY-5074]], mevalonate degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5074 PWY-5074]
 +
** '''1''' reactions found over '''2''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
−
* Category: [[manual]]
+
* Category: [[orthology]]
−
** Source: [[manual-import_from_medium]]
+
** Source: [[orthology-aragem]]
−
*** Comment: [[added to manage seeds from boundary to extracellular compartment]]
+
*** Tool: [[pantograph]]
 +
* Category: [[annotation]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
−
{{#set: direction=REVERSIBLE}}
+
* RHEA:
−
{{#set: in pathway=}}
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=24404 24404]
−
{{#set: reconstruction category=manual}}
+
* LIGAND-RXN:
−
{{#set: reconstruction source=manual-import_from_medium}}
+
** [http://www.genome.jp/dbget-bin/www_bget?R01360 R01360]
−
{{#set: reconstruction comment=added to manage seeds from boundary to extracellular compartment}}
+
* UNIPROT:
 +
** [http://www.uniprot.org/uniprot/P35914 P35914]
 +
** [http://www.uniprot.org/uniprot/P35915 P35915]
 +
** [http://www.uniprot.org/uniprot/Q8L7K2 Q8L7K2]
 +
{{#set: direction=LEFT-TO-RIGHT}}
 +
{{#set: common name=Hydroxymethylglutaryl-CoA lyase}}
 +
{{#set: ec number=EC-4.1.3.4}}
 +
{{#set: gene associated=Ec-26_006120}}
 +
{{#set: in pathway=PWY66-367|LEU-DEG2-PWY|PWY-5074}}
 +
{{#set: reconstruction category=orthology|annotation}}
 +
{{#set: reconstruction source=annotation-esiliculosus_genome|orthology-aragem}}
 +
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 20:43, 21 March 2018

Reaction HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • Hydroxymethylglutaryl-CoA lyase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY66-367, ketogenesis: PWY66-367
    • 3 reactions found over 5 reactions in the full pathway
  • LEU-DEG2-PWY, L-leucine degradation I: LEU-DEG2-PWY
    • 6 reactions found over 6 reactions in the full pathway
  • PWY-5074, mevalonate degradation: PWY-5074
    • 1 reactions found over 2 reactions in the full pathway

Reconstruction information

External links





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