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| Line 1: |
Line 1: |
| | [[Category:Metabolite]] | | [[Category:Metabolite]] |
| − | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=NAD NAD] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=PYRIDOXINE PYRIDOXINE] == |
| | * smiles: | | * smiles: |
| − | ** C1(C(=CC=C[N+]=1C5(OC(COP(=O)([O-])OP(=O)([O-])OCC2(OC(C(O)C(O)2)N4(C=NC3(C(N)=NC=NC=34))))C(O)C(O)5))C(N)=O) | + | ** CC1(=NC=C(C(=C1O)CO)CO) |
| | * inchi key: | | * inchi key: |
| − | ** InChIKey=BAWFJGJZGIEFAR-NNYOXOHSSA-M | + | ** InChIKey=LXNHXLLTXMVWPM-UHFFFAOYSA-N |
| | * common name: | | * common name: |
| − | ** NAD+ | + | ** pyridoxine |
| | * molecular weight: | | * molecular weight: |
| − | ** 662.422 | + | ** 169.18 |
| | * Synonym(s): | | * Synonym(s): |
| − | ** NAD+ | + | ** vitamin B6 |
| − | ** beta-nicotinamide adenine dinucleotide | + | ** 2-methyl-3-hydroxy-4,5-bis(hydroxy-methyl) pyridine |
| − | ** coenzyme I
| + | ** pyridoxol |
| − | ** diphosphopyridine nucleotide
| + | |
| − | ** diphosphopyridine nucleotide oxidized
| + | |
| − | ** nicotinamide adenine dinucleotide
| + | |
| − | ** nicotinamide adenine dinucleotide oxidized
| + | |
| − | ** NAD-oxidized
| + | |
| − | ** NAD-ox
| + | |
| − | ** DPN+
| + | |
| − | ** DPN-ox
| + | |
| − | ** DPN
| + | |
| − | ** β-nicotinamide adenine dinucleotide
| + | |
| − | ** NAD | + | |
| − | ** β-NAD+
| + | |
| | | | |
| | == Reaction(s) known to consume the compound == | | == Reaction(s) known to consume the compound == |
| − | * [[RXN-8001]] | + | * [[PNKIN-RXN]] |
| − | * [[RXN-12789]]
| + | |
| − | * [[RXN-17777]]
| + | |
| − | * [[1.2.1.65-RXN]]
| + | |
| − | * [[RXN-17115]]
| + | |
| − | * [[RXN-12490]]
| + | |
| − | * [[RXN66-479]]
| + | |
| − | * [[RXN-17794]]
| + | |
| − | * [[RXN-14116]]
| + | |
| − | * [[RXN-17790]]
| + | |
| − | * [[RXN-12705]]
| + | |
| − | * [[1.8.1.4-RXN]]
| + | |
| − | * [[RXN66-3]]
| + | |
| − | * [[1.5.1.9-RXN]]
| + | |
| − | * [[RXN-17798]]
| + | |
| − | * [[RXN-2902]]
| + | |
| − | * [[QUINATE-5-DEHYDROGENASE-RXN]]
| + | |
| − | * [[PREPHENATEDEHYDROG-RXN]]
| + | |
| − | * [[RXN-905]]
| + | |
| − | * [[RXN-10715]]
| + | |
| − | * [[RXN-12507]]
| + | |
| − | * [[PYRUVDEH-RXN]]
| + | |
| − | * [[RXN-7682]]
| + | |
| − | * [[RXN-12750]]
| + | |
| − | * [[2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN]]
| + | |
| − | * [[1.5.1.15-RXN]]
| + | |
| − | * [[PYRNUTRANSHYDROGEN-RXN]]
| + | |
| − | * [[2OXOGLUTARATEDEH-RXN]]
| + | |
| − | * [[GLYCOLALD-DEHYDROG-RXN]]
| + | |
| − | * [[RXN-37]]
| + | |
| − | * [[RXN-7745]]
| + | |
| − | * [[OHACYL-COA-DEHYDROG-RXN]]
| + | |
| − | * [[NAD-KIN-RXN]]
| + | |
| − | * [[RXN-11213]]
| + | |
| − | * [[RXN66-472]]
| + | |
| − | * [[RXN-1884]]
| + | |
| − | * [[HISTALDEHYD-RXN]]
| + | |
| − | * [[RXN-10698]]
| + | |
| − | * [[RXN66-476]]
| + | |
| − | * [[RXN-12693]]
| + | |
| − | * [[RXN-17781]]
| + | |
| − | * [[RXN-16559]]
| + | |
| − | * [[RXN-3341]]
| + | |
| − | * [[RXN-14271]]
| + | |
| − | * [[1.1.1.39-RXN]]
| + | |
| − | * [[RXN-13158]]
| + | |
| − | * [[DHBDEHYD-RXN]]
| + | |
| − | * [[RXN-16136]]
| + | |
| − | * [[UGD-RXN]]
| + | |
| − | * [[RXN-10702]]
| + | |
| − | * [[2.7.1.160-RXN]]
| + | |
| − | * [[RXN-10780]]
| + | |
| − | * [[1.2.1.27-RXN]]
| + | |
| − | * [[RXN-10703]]
| + | |
| − | * [[ALDHDEHYDROG-RXN]]
| + | |
| − | * [[RXN-7790]]
| + | |
| − | * [[RXN-13414]]
| + | |
| − | * [[RXN-14986]]
| + | |
| − | * [[RXN0-1132]]
| + | |
| − | * [[RXN-17786]]
| + | |
| − | * [[2-KETO-ADIPATE-DEHYDROG-RXN]]
| + | |
| − | * [[RXN0-5248]]
| + | |
| − | * [[3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN]]
| + | |
| − | * [[CYCLOHEXADIENYL-DEHYDROGENASE-RXN]]
| + | |
| − | * [[GDP-MANNOSE-6-DEHYDROGENASE-RXN]]
| + | |
| − | * [[R222-RXN]]
| + | |
| − | * [[1.2.1.25-RXN]]
| + | |
| − | * [[RXN-10089]]
| + | |
| − | * [[RXN-11245]]
| + | |
| | == Reaction(s) known to produce the compound == | | == Reaction(s) known to produce the compound == |
| − | * [[RXN-11195]]
| |
| − | * [[TRANS-RXN0-277]]
| |
| − | * [[RXN0-5330]]
| |
| − | * [[GLUTAMATE-SYNTHASE-NADH-RXN]]
| |
| − | * [[RXN-10062]]
| |
| − | * [[RXN-11478]]
| |
| − | * [[1.5.1.20-RXN]]
| |
| − | * [[RXN-3661]]
| |
| − | * [[RXN1G-488]]
| |
| − | * [[RXN1G-526]]
| |
| − | * [[RXN-9659]]
| |
| − | * [[RXN-9658]]
| |
| − | * [[RXN-10911]]
| |
| − | * [[RXN-11482]]
| |
| − | * [[RXN-9635]]
| |
| − | * [[ENOYL-ACP-REDUCT-NADH-RXN]]
| |
| − | * [[RXN-16632]]
| |
| − | * [[RXN-10657]]
| |
| − | * [[RXN-16628]]
| |
| − | * [[RXN-16620]]
| |
| − | * [[RXN-16624]]
| |
| − | * [[TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN-CPD-10279/NAD//CPD-14281/NADH/PROTON.37.]]
| |
| − | * [[1.5.1.20-RXN-5-METHYL-THF/NAD//METHYLENE-THF/NADH/PROTON.44.]]
| |
| − | * [[RXN0-2145]]
| |
| − | * [[RXN1G-395]]
| |
| − | * [[CYTOCHROME-B5-REDUCTASE-RXN]]
| |
| − | * [[1.6.5.4-RXN]]
| |
| − | * [[RXN-9662]]
| |
| − | * [[RXN-9663]]
| |
| − | * [[RXN-9660]]
| |
| − | * [[RXN-9661]]
| |
| − | * [[NAD-SYNTH-NH3-RXN]]
| |
| − | * [[RXN-12570]]
| |
| − | * [[RXN-5822]]
| |
| − | * [[RXN-9657]]
| |
| − | * [[RXN-9558]]
| |
| − | * [[RXN-10661]]
| |
| − | * [[NITRATE-REDUCTASE-NADH-RXN]]
| |
| − | * [[RXN-9510]]
| |
| − | * [[NAD-SYNTH-GLN-RXN]]
| |
| − | * [[RXN-13417]]
| |
| | == Reaction(s) of unknown directionality == | | == Reaction(s) of unknown directionality == |
| − | * [[RXN-7719]]
| |
| − | * [[NADH-DEHYDROG-A-RXN]]
| |
| − | * [[GCVMULTI-RXN]]
| |
| − | * [[PHENDEHYD-RXN]]
| |
| − | * [[RXN0-901]]
| |
| − | * [[RXN-7644]]
| |
| − | * [[RXN-7716]]
| |
| − | * [[GLUTAMATE-DEHYDROGENASE-RXN]]
| |
| − | * [[RXN0-2044]]
| |
| − | * [[IMP-DEHYDROG-RXN]]
| |
| − | * [[RXN-14280]]
| |
| − | * [[GLYCOLATE-REDUCTASE-RXN]]
| |
| − | * [[MANNPDEHYDROG-RXN]]
| |
| − | * [[ALANINE-DEHYDROGENASE-RXN]]
| |
| − | * [[RR-BUTANEDIOL-DEHYDROGENASE-RXN]]
| |
| − | * [[NADH-DEHYDROGENASE-RXN]]
| |
| − | * [[RXN-8629]]
| |
| − | * [[RXN-11662]]
| |
| − | * [[L-IDITOL-2-DEHYDROGENASE-RXN]]
| |
| − | * [[L-AMINO-ACID-DEHYDROGENASE-RXN-TYR/NAD/WATER//P-HYDROXY-PHENYLPYRUVATE/AMMONIUM/NADH/PROTON.61.]]
| |
| − | * [[RETINOL-DEHYDROGENASE-RXN]]
| |
| − | * [[HISTOLDEHYD-RXN]]
| |
| − | * [[RIBITOL-2-DEHYDROGENASE-RXN]]
| |
| − | * [[1.1.1.178-RXN]]
| |
| − | * [[MALATE-DEH-RXN]]
| |
| − | * [[2KETO-3METHYLVALERATE-RXN]]
| |
| − | * [[1.1.1.8-RXN]]
| |
| − | * [[MYO-INOSITOL-2-DEHYDROGENASE-RXN]]
| |
| − | * [[RXN-1302]]
| |
| − | * [[3-ISOPROPYLMALDEHYDROG-RXN]]
| |
| − | * [[BENZALDEHYDE-DEHYDROGENASE-NAD+-RXN]]
| |
| − | * [[1.1.1.145-RXN]]
| |
| − | * [[BADH-RXN]]
| |
| − | * [[RXN-16133]]
| |
| − | * [[GAPOXNPHOSPHN-RXN]]
| |
| − | * [[NAD+-ADP-RIBOSYLTRANSFERASE-RXN]]
| |
| − | * [[FUMARATE-REDUCTASE-NADH-RXN]]
| |
| − | * [[PGLYCDEHYDROG-RXN]]
| |
| − | * [[GCVMULTI-RXN-GLY/THF/NAD//METHYLENE-THF/AMMONIUM/CARBON-DIOXIDE/NADH.56.]]
| |
| − | * [[1.3.1.9-RXN]]
| |
| − | * [[RXN0-276]]
| |
| − | * [[RXN-14225]]
| |
| − | * [[RXN-14224]]
| |
| − | * [[L-LACTATE-DEHYDROGENASE-RXN]]
| |
| | == External links == | | == External links == |
| − | * CAS : 53-84-9 | + | * CAS : 65-23-6 |
| − | * BIGG : 33480 | + | * BIGG : 34590 |
| | + | * DRUGBANK : DB00165 |
| | * PUBCHEM: | | * PUBCHEM: |
| − | ** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=15938971 15938971] | + | ** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=1054 1054] |
| − | * HMDB : HMDB00902 | + | * HMDB : HMDB00239 |
| | * LIGAND-CPD: | | * LIGAND-CPD: |
| − | ** [http://www.genome.jp/dbget-bin/www_bget?C00003 C00003] | + | ** [http://www.genome.jp/dbget-bin/www_bget?C00314 C00314] |
| | * CHEMSPIDER: | | * CHEMSPIDER: |
| − | ** [http://www.chemspider.com/Chemical-Structure.10239196.html 10239196] | + | ** [http://www.chemspider.com/Chemical-Structure.1025.html 1025] |
| | * CHEBI: | | * CHEBI: |
| − | ** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57540 57540] | + | ** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=16709 16709] |
| − | * METABOLIGHTS : MTBLC57540 | + | * METABOLIGHTS : MTBLC16709 |
| − | {{#set: smiles=C1(C(=CC=C[N+]=1C5(OC(COP(=O)([O-])OP(=O)([O-])OCC2(OC(C(O)C(O)2)N4(C=NC3(C(N)=NC=NC=34))))C(O)C(O)5))C(N)=O)}} | + | {{#set: smiles=CC1(=NC=C(C(=C1O)CO)CO)}} |
| − | {{#set: inchi key=InChIKey=BAWFJGJZGIEFAR-NNYOXOHSSA-M}} | + | {{#set: inchi key=InChIKey=LXNHXLLTXMVWPM-UHFFFAOYSA-N}} |
| − | {{#set: common name=NAD+}} | + | {{#set: common name=pyridoxine}} |
| − | {{#set: molecular weight=662.422 }} | + | {{#set: molecular weight=169.18 }} |
| − | {{#set: common name=NAD+|beta-nicotinamide adenine dinucleotide|coenzyme I|diphosphopyridine nucleotide|diphosphopyridine nucleotide oxidized|nicotinamide adenine dinucleotide|nicotinamide adenine dinucleotide oxidized|NAD-oxidized|NAD-ox|DPN+|DPN-ox|DPN|β-nicotinamide adenine dinucleotide|NAD|β-NAD+}} | + | {{#set: common name=vitamin B6|2-methyl-3-hydroxy-4,5-bis(hydroxy-methyl) pyridine|pyridoxol}} |
| − | {{#set: consumed by=RXN-8001|RXN-12789|RXN-17777|1.2.1.65-RXN|RXN-17115|RXN-12490|RXN66-479|RXN-17794|RXN-14116|RXN-17790|RXN-12705|1.8.1.4-RXN|RXN66-3|1.5.1.9-RXN|RXN-17798|RXN-2902|QUINATE-5-DEHYDROGENASE-RXN|PREPHENATEDEHYDROG-RXN|RXN-905|RXN-10715|RXN-12507|PYRUVDEH-RXN|RXN-7682|RXN-12750|2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN|1.5.1.15-RXN|PYRNUTRANSHYDROGEN-RXN|2OXOGLUTARATEDEH-RXN|GLYCOLALD-DEHYDROG-RXN|RXN-37|RXN-7745|OHACYL-COA-DEHYDROG-RXN|NAD-KIN-RXN|RXN-11213|RXN66-472|RXN-1884|HISTALDEHYD-RXN|RXN-10698|RXN66-476|RXN-12693|RXN-17781|RXN-16559|RXN-3341|RXN-14271|1.1.1.39-RXN|RXN-13158|DHBDEHYD-RXN|RXN-16136|UGD-RXN|RXN-10702|2.7.1.160-RXN|RXN-10780|1.2.1.27-RXN|RXN-10703|ALDHDEHYDROG-RXN|RXN-7790|RXN-13414|RXN-14986|RXN0-1132|RXN-17786|2-KETO-ADIPATE-DEHYDROG-RXN|RXN0-5248|3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN|CYCLOHEXADIENYL-DEHYDROGENASE-RXN|GDP-MANNOSE-6-DEHYDROGENASE-RXN|R222-RXN|1.2.1.25-RXN|RXN-10089|RXN-11245}}
| + | {{#set: consumed by=PNKIN-RXN}} |
| − | {{#set: produced by=RXN-11195|TRANS-RXN0-277|RXN0-5330|GLUTAMATE-SYNTHASE-NADH-RXN|RXN-10062|RXN-11478|1.5.1.20-RXN|RXN-3661|RXN1G-488|RXN1G-526|RXN-9659|RXN-9658|RXN-10911|RXN-11482|RXN-9635|ENOYL-ACP-REDUCT-NADH-RXN|RXN-16632|RXN-10657|RXN-16628|RXN-16620|RXN-16624|TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN-CPD-10279/NAD//CPD-14281/NADH/PROTON.37.|1.5.1.20-RXN-5-METHYL-THF/NAD//METHYLENE-THF/NADH/PROTON.44.|RXN0-2145|RXN1G-395|CYTOCHROME-B5-REDUCTASE-RXN|1.6.5.4-RXN|RXN-9662|RXN-9663|RXN-9660|RXN-9661|NAD-SYNTH-NH3-RXN|RXN-12570|RXN-5822|RXN-9657|RXN-9558|RXN-10661|NITRATE-REDUCTASE-NADH-RXN|RXN-9510|NAD-SYNTH-GLN-RXN|RXN-13417}}
| + | |
| − | {{#set: consumed or produced by=RXN-7719|NADH-DEHYDROG-A-RXN|GCVMULTI-RXN|PHENDEHYD-RXN|RXN0-901|RXN-7644|RXN-7716|GLUTAMATE-DEHYDROGENASE-RXN|RXN0-2044|IMP-DEHYDROG-RXN|RXN-14280|GLYCOLATE-REDUCTASE-RXN|MANNPDEHYDROG-RXN|ALANINE-DEHYDROGENASE-RXN|RR-BUTANEDIOL-DEHYDROGENASE-RXN|NADH-DEHYDROGENASE-RXN|RXN-8629|RXN-11662|L-IDITOL-2-DEHYDROGENASE-RXN|L-AMINO-ACID-DEHYDROGENASE-RXN-TYR/NAD/WATER//P-HYDROXY-PHENYLPYRUVATE/AMMONIUM/NADH/PROTON.61.|RETINOL-DEHYDROGENASE-RXN|HISTOLDEHYD-RXN|RIBITOL-2-DEHYDROGENASE-RXN|1.1.1.178-RXN|MALATE-DEH-RXN|2KETO-3METHYLVALERATE-RXN|1.1.1.8-RXN|MYO-INOSITOL-2-DEHYDROGENASE-RXN|RXN-1302|3-ISOPROPYLMALDEHYDROG-RXN|BENZALDEHYDE-DEHYDROGENASE-NAD+-RXN|1.1.1.145-RXN|BADH-RXN|RXN-16133|GAPOXNPHOSPHN-RXN|NAD+-ADP-RIBOSYLTRANSFERASE-RXN|FUMARATE-REDUCTASE-NADH-RXN|PGLYCDEHYDROG-RXN|GCVMULTI-RXN-GLY/THF/NAD//METHYLENE-THF/AMMONIUM/CARBON-DIOXIDE/NADH.56.|1.3.1.9-RXN|RXN0-276|RXN-14225|RXN-14224|L-LACTATE-DEHYDROGENASE-RXN}} | + | |
