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| [[Category:Reaction]] | | [[Category:Reaction]] |
− | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=ISOCITDEH-RXN ISOCITDEH-RXN] == | + | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN0-5222 RXN0-5222] == |
| * direction: | | * direction: |
− | ** REVERSIBLE | + | ** LEFT-TO-RIGHT |
| * common name: | | * common name: |
− | ** isocitrate dehydrogenase (NADP+) | + | ** cyanase |
− | * ec number:
| + | |
− | ** [http://enzyme.expasy.org/EC/1.1.1.42 EC-1.1.1.42]
| + | |
| * Synonym(s): | | * Synonym(s): |
| + | ** cyanate lyase |
| + | ** cyanate hydrolase |
| + | ** cyanate aminohydrolase |
| + | ** cyanate C-N-lyase |
| + | ** cyanate hydratase |
| | | |
| == Reaction Formula == | | == Reaction Formula == |
| * With identifiers: | | * With identifiers: |
− | ** 1 [[THREO-DS-ISO-CITRATE]][c] '''+''' 1 [[NADP]][c] '''<=>''' 1 [[2-KETOGLUTARATE]][c] '''+''' 1 [[NADPH]][c] '''+''' 1 [[CARBON-DIOXIDE]][c] | + | ** 2 [[PROTON]][c] '''+''' 1 [[CARBAMATE]][c] '''=>''' 1 [[AMMONIUM]][c] '''+''' 1 [[CARBON-DIOXIDE]][c] |
| * With common name(s): | | * With common name(s): |
− | ** 1 D-threo-isocitrate[c] '''+''' 1 NADP+[c] '''<=>''' 1 2-oxoglutarate[c] '''+''' 1 NADPH[c] '''+''' 1 CO2[c] | + | ** 2 H+[c] '''+''' 1 carbamate[c] '''=>''' 1 ammonium[c] '''+''' 1 CO2[c] |
| | | |
| == Genes associated with this reaction == | | == Genes associated with this reaction == |
− | Genes have been associated with this reaction based on different elements listed below.
| |
− | * [[Ec-11_003080]]
| |
− | ** ESILICULOSUS_GENOME
| |
− | ***GO-TERM
| |
| == Pathways == | | == Pathways == |
− | * [[PWY-5913]], partial TCA cycle (obligate autotrophs): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5913 PWY-5913] | + | * [[CYANCAT-PWY]], cyanate degradation: [http://metacyc.org/META/NEW-IMAGE?object=CYANCAT-PWY CYANCAT-PWY] |
− | ** '''10''' reactions found over '''11''' reactions in the full pathway
| + | ** '''2''' reactions found over '''3''' reactions in the full pathway |
− | * [[PWY-6549]], L-glutamine biosynthesis III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6549 PWY-6549]
| + | * [[PWY0-1471]], uracil degradation III: [http://metacyc.org/META/NEW-IMAGE?object=PWY0-1471 PWY0-1471] |
− | ** '''8''' reactions found over '''9''' reactions in the full pathway
| + | ** '''1''' reactions found over '''6''' reactions in the full pathway |
− | * [[PWY-7268]], NAD/NADP-NADH/NADPH cytosolic interconversion (yeast): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7268 PWY-7268]
| + | |
− | ** '''4''' reactions found over '''5''' reactions in the full pathway | + | |
− | * [[TCA]], TCA cycle I (prokaryotic): [http://metacyc.org/META/NEW-IMAGE?object=TCA TCA]
| + | |
− | ** '''9''' reactions found over '''10''' reactions in the full pathway
| + | |
− | * [[P23-PWY]], reductive TCA cycle I: [http://metacyc.org/META/NEW-IMAGE?object=P23-PWY P23-PWY]
| + | |
− | ** '''10''' reactions found over '''12''' reactions in the full pathway
| + | |
− | * [[P105-PWY]], TCA cycle IV (2-oxoglutarate decarboxylase): [http://metacyc.org/META/NEW-IMAGE?object=P105-PWY P105-PWY]
| + | |
− | ** '''9''' reactions found over '''11''' reactions in the full pathway
| + | |
− | * [[FERMENTATION-PWY]], mixed acid fermentation: [http://metacyc.org/META/NEW-IMAGE?object=FERMENTATION-PWY FERMENTATION-PWY] | + | |
− | ** '''8''' reactions found over '''16''' reactions in the full pathway
| + | |
− | * [[PWY-6728]], methylaspartate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6728 PWY-6728]
| + | |
− | ** '''11''' reactions found over '''18''' reactions in the full pathway
| + | |
− | * [[REDCITCYC]], TCA cycle VIII (helicobacter): [http://metacyc.org/META/NEW-IMAGE?object=REDCITCYC REDCITCYC]
| + | |
− | ** '''5''' reactions found over '''9''' reactions in the full pathway
| + | |
− | * [[PWY-7254]], TCA cycle VII (acetate-producers): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7254 PWY-7254]
| + | |
− | ** '''7''' reactions found over '''9''' reactions in the full pathway
| + | |
− | * [[PWY-7124]], ethylene biosynthesis V (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7124 PWY-7124]
| + | |
− | ** '''8''' reactions found over '''10''' reactions in the full pathway
| + | |
− | * [[PWY-6969]], TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6969 PWY-6969]
| + | |
− | ** '''10''' reactions found over '''12''' reactions in the full pathway | + | |
| == Reconstruction information == | | == Reconstruction information == |
− | * [[annotation]]: | + | * Category: [[annotation]] |
− | ** [[pathwaytools]]: | + | ** Source: [[annotation-esiliculosus_genome]] |
− | *** [[esiliculosus_genome]] | + | *** Tool: [[pathwaytools]] |
| == External links == | | == External links == |
| + | * RHEA: |
| + | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=15649 15649] |
| * LIGAND-RXN: | | * LIGAND-RXN: |
− | ** [http://www.genome.jp/dbget-bin/www_bget?R00267 R00267] | + | ** [http://www.genome.jp/dbget-bin/www_bget?R07316 R07316] |
− | * PIR:
| + | {{#set: direction=LEFT-TO-RIGHT}} |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A10759 A10759]
| + | {{#set: common name=cyanase}} |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A43294 A43294]
| + | {{#set: common name=cyanate lyase|cyanate hydrolase|cyanate aminohydrolase|cyanate C-N-lyase|cyanate hydratase}} |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A43934 A43934]
| + | {{#set: in pathway=CYANCAT-PWY|PWY0-1471}} |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A49341 A49341]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A54756 A54756]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A55591 A55591]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=B49341 B49341]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=C64523 C64523]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=C81399 C81399]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=DCBYIS DCBYIS]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=DCECIS DCECIS]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=G69330 G69330]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=H64389 H64389]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=H81877 H81877]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=H86708 H86708]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=I40382 I40382]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=I40719 I40719]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=JC4600 JC4600]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S28423 S28423]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S33612 S33612]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S33859 S33859]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S47013 S47013]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S51419 S51419]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S57499 S57499]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S62921 S62921]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S65065 S65065]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S74684 S74684]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T04355 T04355]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T04356 T04356]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T07402 T07402]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T09619 T09619]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T39058 T39058]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T44658 T44658]
| + | |
− | ** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T46280 T46280]
| + | |
− | * UNIPROT:
| + | |
− | ** [http://www.uniprot.org/uniprot/P16100 P16100]
| + | |
− | ** [http://www.uniprot.org/uniprot/P33198 P33198]
| + | |
− | ** [http://www.uniprot.org/uniprot/P41561 P41561]
| + | |
− | ** [http://www.uniprot.org/uniprot/P41562 P41562]
| + | |
− | ** [http://www.uniprot.org/uniprot/P50214 P50214]
| + | |
− | ** [http://www.uniprot.org/uniprot/P41560 P41560]
| + | |
− | ** [http://www.uniprot.org/uniprot/P56063 P56063]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9PHY3 Q9PHY3]
| + | |
− | ** [http://www.uniprot.org/uniprot/P21954 P21954]
| + | |
− | ** [http://www.uniprot.org/uniprot/P08200 P08200]
| + | |
− | ** [http://www.uniprot.org/uniprot/O29610 O29610]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9JUV7 Q9JUV7]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9CHQ4 Q9CHQ4]
| + | |
− | ** [http://www.uniprot.org/uniprot/P39126 P39126]
| + | |
− | ** [http://www.uniprot.org/uniprot/P50216 P50216]
| + | |
− | ** [http://www.uniprot.org/uniprot/P50215 P50215]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q04467 Q04467]
| + | |
− | ** [http://www.uniprot.org/uniprot/P50217 P50217]
| + | |
− | ** [http://www.uniprot.org/uniprot/P41939 P41939]
| + | |
− | ** [http://www.uniprot.org/uniprot/P48735 P48735]
| + | |
− | ** [http://www.uniprot.org/uniprot/P53982 P53982]
| + | |
− | ** [http://www.uniprot.org/uniprot/P50218 P50218]
| + | |
− | ** [http://www.uniprot.org/uniprot/O65853 O65853]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q40345 Q40345]
| + | |
− | ** [http://www.uniprot.org/uniprot/O14254 O14254]
| + | |
− | ** [http://www.uniprot.org/uniprot/O75874 O75874]
| + | |
− | {{#set: direction=REVERSIBLE}} | + | |
− | {{#set: common name=isocitrate dehydrogenase (NADP+)}} | + | |
− | {{#set: ec number=EC-1.1.1.42}} | + | |
− | {{#set: gene associated=Ec-11_003080}}
| + | |
− | {{#set: in pathway=PWY-5913|PWY-6549|PWY-7268|TCA|P23-PWY|P105-PWY|FERMENTATION-PWY|PWY-6728|REDCITCYC|PWY-7254|PWY-7124|PWY-6969}} | + | |
| {{#set: reconstruction category=annotation}} | | {{#set: reconstruction category=annotation}} |
| + | {{#set: reconstruction source=annotation-esiliculosus_genome}} |
| {{#set: reconstruction tool=pathwaytools}} | | {{#set: reconstruction tool=pathwaytools}} |
− | {{#set: reconstruction source=esiliculosus_genome}}
| |