Difference between revisions of "Ec-21 001700"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=L-THYROXINE L-THYROXINE] == * smiles: ** C(=O)([O-])C([N+])CC1(C=C(I)C(=C(I)C=1)OC2(=CC(I)=C(O)...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=6PGLUCONDEHYDROG-RXN 6PGLUCONDEHYDROG-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** phosp...")
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[[Category:Metabolite]]
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[[Category:Reaction]]
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=L-THYROXINE L-THYROXINE] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=6PGLUCONDEHYDROG-RXN 6PGLUCONDEHYDROG-RXN] ==
* smiles:
+
* direction:
** C(=O)([O-])C([N+])CC1(C=C(I)C(=C(I)C=1)OC2(=CC(I)=C(O)C(I)=C2))
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** LEFT-TO-RIGHT
* inchi key:
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** InChIKey=XUIIKFGFIJCVMT-LBPRGKRZSA-N
+
 
* common name:
 
* common name:
** L-thyroxine
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** phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]
* molecular weight:
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** phosphogluconate dehydrogenase (decarboxylating)
** 776.874   
+
* ec number:
 +
** [http://enzyme.expasy.org/EC/1.1.1.351 EC-1.1.1.351]
 
* Synonym(s):
 
* Synonym(s):
** levothyroxine
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** 6PGD
** 3,3',5,5'-tetraiodo-L-thyronine
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** 6-phosphogluconic carboxylase
** 3,5,3',5'-tetraiodo-L-thyronine
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** 6-phosphogluconic dehydrogenase
** 4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-L-phenylalanine
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** Phosphogluconic acid dehydrogenase
** levothyroxin
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** O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine
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** T4
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** L-T4
+
  
== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
* [[RXN-10614]]
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* With identifiers:
== Reaction(s) known to produce the compound ==
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** 1 [[NAD-P-OR-NOP]][c] '''+''' 1 [[CPD-2961]][c] '''=>''' 1 [[CARBON-DIOXIDE]][c] '''+''' 1 [[NADH-P-OR-NOP]][c] '''+''' 1 [[RIBULOSE-5P]][c]
== Reaction(s) of unknown directionality ==
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* With common name(s):
 +
** 1 NAD(P)+[c] '''+''' 1 D-gluconate 6-phosphate[c] '''=>''' 1 CO2[c] '''+''' 1 NAD(P)H[c] '''+''' 1 D-ribulose 5-phosphate[c]
 +
 
 +
== Genes associated with this reaction  ==
 +
Genes have been associated with this reaction based on different elements listed below.
 +
* [[Ec-01_008450]]
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** ESILICULOSUS_GENOME
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***GO-TERM
 +
* [[Ec-12_007690]]
 +
** [[pantograph]]-[[aragem]]
 +
** [[pantograph]]-[[aragem]]
 +
== Pathways  ==
 +
* [[P122-PWY]], heterolactic fermentation: [http://metacyc.org/META/NEW-IMAGE?object=P122-PWY P122-PWY]
 +
** '''13''' reactions found over '''18''' reactions in the full pathway
 +
== Reconstruction information  ==
 +
* Category: [[orthology]]
 +
** Source: [[orthology-aragem]]
 +
*** Tool: [[pantograph]]
 +
* Category: [[annotation]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
* CAS : 51-48-9
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* RHEA:
* DRUGBANK : DB00451
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=10116 10116]
* PUBCHEM:
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* UNIPROT:
** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=25201348 25201348]
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** [http://www.uniprot.org/uniprot/P14332 P14332]
* HMDB : HMDB00248
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** [http://www.uniprot.org/uniprot/P31072 P31072]
* LIGAND-CPD:
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** [http://www.uniprot.org/uniprot/Q9CDN4 Q9CDN4]
** [http://www.genome.jp/dbget-bin/www_bget?C01829 C01829]
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** [http://www.uniprot.org/uniprot/P47506 P47506]
* CHEMSPIDER:
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** [http://www.uniprot.org/uniprot/Q9JWS3 Q9JWS3]
** [http://www.chemspider.com/Chemical-Structure.5614.html 5614]
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** [http://www.uniprot.org/uniprot/P43774 P43774]
* CHEBI:
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** [http://www.uniprot.org/uniprot/P12013 P12013]
** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=58448 58448]
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** [http://www.uniprot.org/uniprot/P41576 P41576]
* METABOLIGHTS : MTBLC18332
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** [http://www.uniprot.org/uniprot/P00350 P00350]
{{#set: smiles=C(=O)([O-])C([N+])CC1(C=C(I)C(=C(I)C=1)OC2(=CC(I)=C(O)C(I)=C2))}}
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** [http://www.uniprot.org/uniprot/P00349 P00349]
{{#set: inchi key=InChIKey=XUIIKFGFIJCVMT-LBPRGKRZSA-N}}
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** [http://www.uniprot.org/uniprot/P52209 P52209]
{{#set: common name=L-thyroxine}}
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** [http://www.uniprot.org/uniprot/P41581 P41581]
{{#set: molecular weight=776.874    }}
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** [http://www.uniprot.org/uniprot/P41582 P41582]
{{#set: common name=levothyroxine|3,3',5,5'-tetraiodo-L-thyronine|3,5,3',5'-tetraiodo-L-thyronine|4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-L-phenylalanine|levothyroxin|O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine|T4|L-T4}}
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** [http://www.uniprot.org/uniprot/Q59275 Q59275]
{{#set: consumed by=RXN-10614}}
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** [http://www.uniprot.org/uniprot/P41583 P41583]
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** [http://www.uniprot.org/uniprot/Q60254 Q60254]
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** [http://www.uniprot.org/uniprot/P37754 P37754]
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** [http://www.uniprot.org/uniprot/Q59410 Q59410]
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** [http://www.uniprot.org/uniprot/P52207 P52207]
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** [http://www.uniprot.org/uniprot/P70718 P70718]
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** [http://www.uniprot.org/uniprot/Q7M451 Q7M451]
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** [http://www.uniprot.org/uniprot/P41572 P41572]
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** [http://www.uniprot.org/uniprot/P14062 P14062]
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** [http://www.uniprot.org/uniprot/P21577 P21577]
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** [http://www.uniprot.org/uniprot/P38720 P38720]
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** [http://www.uniprot.org/uniprot/Q40311 Q40311]
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** [http://www.uniprot.org/uniprot/P53319 P53319]
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** [http://www.uniprot.org/uniprot/O81237 O81237]
 +
** [http://www.uniprot.org/uniprot/O81238 O81238]
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** [http://www.uniprot.org/uniprot/O81239 O81239]
 +
** [http://www.uniprot.org/uniprot/O22111 O22111]
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** [http://www.uniprot.org/uniprot/Q17761 Q17761]
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** [http://www.uniprot.org/uniprot/O32911 O32911]
 +
{{#set: direction=LEFT-TO-RIGHT}}
 +
{{#set: common name=phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]}}
 +
{{#set: common name=phosphogluconate dehydrogenase (decarboxylating)}}
 +
{{#set: ec number=EC-1.1.1.351}}
 +
{{#set: common name=6PGD|6-phosphogluconic carboxylase|6-phosphogluconic dehydrogenase|Phosphogluconic acid dehydrogenase}}
 +
{{#set: gene associated=Ec-01_008450|Ec-12_007690}}
 +
{{#set: in pathway=P122-PWY}}
 +
{{#set: reconstruction category=orthology|annotation}}
 +
{{#set: reconstruction source=annotation-esiliculosus_genome|orthology-aragem}}
 +
{{#set: reconstruction tool=pantograph|pathwaytools}}

Revision as of 22:03, 17 March 2018

Reaction 6PGLUCONDEHYDROG-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]
    • phosphogluconate dehydrogenase (decarboxylating)
  • ec number:
  • Synonym(s):
    • 6PGD
    • 6-phosphogluconic carboxylase
    • 6-phosphogluconic dehydrogenase
    • Phosphogluconic acid dehydrogenase

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • P122-PWY, heterolactic fermentation: P122-PWY
    • 13 reactions found over 18 reactions in the full pathway

Reconstruction information

External links

"phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating" cannot be used as a page name in this wiki.