Difference between revisions of "RXN-16043"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=GDP-MANNOSE GDP-MANNOSE] == * smiles: ** C(OP(=O)([O-])OP(=O)([O-])OC1(OC(C(O)C(O)C(O)1)CO))C2(...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=ISOCIT-CLEAV-RXN ISOCIT-CLEAV-RXN] == * direction: ** REVERSIBLE * common name: ** isocitrate lyase...")
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=GDP-MANNOSE GDP-MANNOSE] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=ISOCIT-CLEAV-RXN ISOCIT-CLEAV-RXN] ==
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* smiles:
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* direction:
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** C(OP(=O)([O-])OP(=O)([O-])OC1(OC(C(O)C(O)C(O)1)CO))C2(C(O)C(O)C(O2)N4(C=NC3(C(=O)NC(N)=NC=34)))
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** REVERSIBLE
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* inchi key:
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** InChIKey=MVMSCBBUIHUTGJ-GDJBGNAASA-L
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* common name:
 
* common name:
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** GDP-α-D-mannose
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** isocitrate lyase
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* molecular weight:
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* ec number:
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** 603.329   
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** [http://enzyme.expasy.org/EC/4.1.3.1 EC-4.1.3.1]
 
* Synonym(s):
 
* Synonym(s):
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** guanosine pyrophosphate mannose
 
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** guanosine diphosphomannose
 
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** guanosine diphosphate mannose
 
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** GDP-mannose
 
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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* [[RXN-5464]]
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* With identifiers:
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* [[GDPMANDEHYDRA-RXN]]
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** 1 [[THREO-DS-ISO-CITRATE]][c] '''<=>''' 1 [[SUC]][c] '''+''' 1 [[GLYOX]][c]
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* [[RXN-5462]]
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* With common name(s):
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* [[2.4.1.83-RXN]]
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** 1 D-threo-isocitrate[c] '''<=>''' 1 succinate[c] '''+''' 1 glyoxylate[c]
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* [[RXN-5463]]
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* [[2.4.1.142-RXN]]
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== Genes associated with this reaction  ==
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* [[RXN-16602]]
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Genes have been associated with this reaction based on different elements listed below.
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* [[GDP-MANNOSE-6-DEHYDROGENASE-RXN]]
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* Gene: [[Ec-12_007550]]
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== Reaction(s) known to produce the compound ==
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** Source: [[annotation-esiliculosus_genome]]
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* [[2.7.7.13-RXN]]
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*** Assignment: GO-TERM
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== Reaction(s) of unknown directionality ==
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== Pathways  ==
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* [[RXN-1882]]
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* [[P105-PWY]], TCA cycle IV (2-oxoglutarate decarboxylase): [http://metacyc.org/META/NEW-IMAGE?object=P105-PWY P105-PWY]
 +
** '''9''' reactions found over '''11''' reactions in the full pathway
 +
* [[GLYOXYLATE-BYPASS]], glyoxylate cycle: [http://metacyc.org/META/NEW-IMAGE?object=GLYOXYLATE-BYPASS GLYOXYLATE-BYPASS]
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** '''6''' reactions found over '''6''' reactions in the full pathway
 +
* [[PWY-6969]], TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6969 PWY-6969]
 +
** '''10''' reactions found over '''12''' reactions in the full pathway
 +
== Reconstruction information  ==
 +
* Category: [[annotation]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* CAS : 18441-12-8
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* RHEA:
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* CAS : 3123-67-9
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=13245 13245]
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* BIGG : 1460457
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* PIR:
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* PUBCHEM:
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A41338 A41338]
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=46878389 46878389]
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=I40713 I40713]
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* HMDB : HMDB01163
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=JA0155 JA0155]
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* LIGAND-CPD:
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=JC6182 JC6182]
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** [http://www.genome.jp/dbget-bin/www_bget?C00096 C00096]
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S26857 S26857]
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* CHEBI:
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S26858 S26858]
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57527 57527]
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S39953 S39953]
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* METABOLIGHTS : MTBLC57527
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S52819 S52819]
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{{#set: smiles=C(OP(=O)([O-])OP(=O)([O-])OC1(OC(C(O)C(O)C(O)1)CO))C2(C(O)C(O)C(O2)N4(C=NC3(C(=O)NC(N)=NC=34)))}}
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S77654 S77654]
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{{#set: inchi key=InChIKey=MVMSCBBUIHUTGJ-GDJBGNAASA-L}}
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T04115 T04115]
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{{#set: common name=GDP-&alpha;-D-mannose}}
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T06353 T06353]
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{{#set: molecular weight=603.329    }}
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T07631 T07631]
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{{#set: common name=guanosine pyrophosphate mannose|guanosine diphosphomannose|guanosine diphosphate mannose|GDP-mannose}}
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T07632 T07632]
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{{#set: consumed by=RXN-5464|GDPMANDEHYDRA-RXN|RXN-5462|2.4.1.83-RXN|RXN-5463|2.4.1.142-RXN|RXN-16602|GDP-MANNOSE-6-DEHYDROGENASE-RXN}}
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T08046 T08046]
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{{#set: produced by=2.7.7.13-RXN}}
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T09774 T09774]
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{{#set: reversible reaction associated=RXN-1882}}
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T09779 T09779]
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T11209 T11209]
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=WZBYI WZBYI]
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=WZCKI WZCKI]
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=WZCNIU WZCNIU]
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=WZCSI WZCSI]
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=WZECIC WZECIC]
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** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=WZRPI WZRPI]
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* LIGAND-RXN:
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** [http://www.genome.jp/dbget-bin/www_bget?R00479 R00479]
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* UNIPROT:
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** [http://www.uniprot.org/uniprot/P28467 P28467]
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** [http://www.uniprot.org/uniprot/P42449 P42449]
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** [http://www.uniprot.org/uniprot/P20699 P20699]
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** [http://www.uniprot.org/uniprot/O13439 O13439]
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** [http://www.uniprot.org/uniprot/P28299 P28299]
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** [http://www.uniprot.org/uniprot/Q12031 Q12031]
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** [http://www.uniprot.org/uniprot/P46831 P46831]
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** [http://www.uniprot.org/uniprot/O24588 O24588]
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** [http://www.uniprot.org/uniprot/P49297 P49297]
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** [http://www.uniprot.org/uniprot/P45456 P45456]
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** [http://www.uniprot.org/uniprot/P45457 P45457]
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** [http://www.uniprot.org/uniprot/Q39577 Q39577]
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** [http://www.uniprot.org/uniprot/Q41084 Q41084]
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** [http://www.uniprot.org/uniprot/Q43097 Q43097]
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** [http://www.uniprot.org/uniprot/P28240 P28240]
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** [http://www.uniprot.org/uniprot/P20014 P20014]
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** [http://www.uniprot.org/uniprot/P17069 P17069]
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** [http://www.uniprot.org/uniprot/P15479 P15479]
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** [http://www.uniprot.org/uniprot/P0A9G6 P0A9G6]
 +
** [http://www.uniprot.org/uniprot/P25248 P25248]
 +
{{#set: direction=REVERSIBLE}}
 +
{{#set: common name=isocitrate lyase}}
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{{#set: ec number=EC-4.1.3.1}}
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{{#set: gene associated=Ec-12_007550}}
 +
{{#set: in pathway=P105-PWY|GLYOXYLATE-BYPASS|PWY-6969}}
 +
{{#set: reconstruction category=annotation}}
 +
{{#set: reconstruction source=annotation-esiliculosus_genome}}
 +
{{#set: reconstruction tool=pathwaytools}}

Revision as of 13:42, 21 March 2018

Reaction ISOCIT-CLEAV-RXN

  • direction:
    • REVERSIBLE
  • common name:
    • isocitrate lyase
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 D-threo-isocitrate[c] <=> 1 succinate[c] + 1 glyoxylate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • P105-PWY, TCA cycle IV (2-oxoglutarate decarboxylase): P105-PWY
    • 9 reactions found over 11 reactions in the full pathway
  • GLYOXYLATE-BYPASS, glyoxylate cycle: GLYOXYLATE-BYPASS
    • 6 reactions found over 6 reactions in the full pathway
  • PWY-6969, TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): PWY-6969
    • 10 reactions found over 12 reactions in the full pathway

Reconstruction information

External links





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