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| Line 1: |
Line 1: |
| | [[Category:Metabolite]] | | [[Category:Metabolite]] |
| − | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CO-A CO-A] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD-3483 CPD-3483] == |
| | * smiles: | | * smiles: |
| − | ** CC(C)(C(O)C(=O)NCCC(=O)NCCS)COP(=O)(OP(=O)(OCC1(OC(C(C1OP([O-])(=O)[O-])O)N3(C2(=C(C(N)=NC=N2)N=C3))))[O-])[O-] | + | ** CC([N+]C(C)(C)CO)C(=O)C1(C=CC=C(Cl)C=1) |
| | * inchi key: | | * inchi key: |
| − | ** InChIKey=RGJOEKWQDUBAIZ-IBOSZNHHSA-J | + | ** InChIKey=AKOAEVOSDHIVFX-UHFFFAOYSA-O |
| | * common name: | | * common name: |
| − | ** coenzyme A | + | ** hydroxybupropion |
| | * molecular weight: | | * molecular weight: |
| − | ** 763.502 | + | ** 256.752 |
| | * Synonym(s): | | * Synonym(s): |
| − | ** CoA
| |
| − | ** co-A-SH
| |
| − | ** co-enzyme-A
| |
| − | ** co-A
| |
| − | ** HS-CoA
| |
| | | | |
| | == Reaction(s) known to consume the compound == | | == Reaction(s) known to consume the compound == |
| − | * [[RXN-2006]]
| |
| − | * [[RXN66-483]]
| |
| − | * [[RXN66-480]]
| |
| − | * [[RXN0-7248]]
| |
| − | * [[RXN66-469]]
| |
| − | * [[RXN66-484]]
| |
| − | * [[RXN-16418]]
| |
| − | * [[RXN-17116]]
| |
| − | * [[RXN-1126]]
| |
| − | * [[2.3.1.176-RXN]]
| |
| − | * [[RXN-14268]]
| |
| − | * [[RXN-16045]]
| |
| − | * [[RXN-15889]]
| |
| − | * [[RXN-2001]]
| |
| − | * [[RXN-16389]]
| |
| − | * [[RXN-16041]]
| |
| − | * [[ACYLCOASYN-RXN]]
| |
| − | * [[RXN-16043]]
| |
| − | * [[RXN-11921]]
| |
| − | * [[RXN-16380]]
| |
| − | * [[RXN-10919]]
| |
| − | * [[RXN-13617]]
| |
| − | * [[ACETATE--COA-LIGASE-RXN]]
| |
| − | * [[RXN-9673]]
| |
| − | * [[ACETOACETATE--COA-LIGASE-RXN]]
| |
| − | * [[RXN-8988]]
| |
| − | * [[PYRUVDEH-RXN]]
| |
| − | * [[ATP-CITRATE-PRO-S--LYASE-RXN]]
| |
| − | * [[RXN-13614]]
| |
| − | * [[RXN-16137]]
| |
| − | * [[RXN-11213]]
| |
| − | * [[2OXOGLUTARATEDEH-RXN]]
| |
| − | * [[RXN-7904]]
| |
| − | * [[2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN]]
| |
| − | * [[TRANS-RXN0-623]]
| |
| − | * [[RXN-12978]]
| |
| − | * [[RXN66-477]]
| |
| − | * [[HOLO-ACP-SYNTH-RXN]]
| |
| − | * [[RXN-12184]]
| |
| − | * [[RXN0-7238]]
| |
| − | * [[RXN-13290]]
| |
| − | * [[LINOLENOYL-RXN]]
| |
| − | * [[RXN0-7239]]
| |
| − | * [[RXN-16393]]
| |
| − | * [[RXN66-474]]
| |
| − | * [[R223-RXN]]
| |
| − | * [[RXN-2902]]
| |
| − | * [[RXN-11917]]
| |
| − | * [[RXN-9644]]
| |
| − | * [[RXN-16401]]
| |
| − | * [[1.2.1.27-RXN]]
| |
| − | * [[PYFLAVOXRE-RXN]]
| |
| − | * [[RXN-7790]]
| |
| − | * [[6.2.1.34-RXN]]
| |
| − | * [[2-KETO-ADIPATE-DEHYDROG-RXN]]
| |
| − | * [[RXN-9623]]
| |
| − | * [[ENTDB-RXN]]
| |
| − | * [[4-COUMARATE--COA-LIGASE-RXN]]
| |
| − | * [[1.2.1.25-RXN]]
| |
| − | * [[RXN-16402]]
| |
| | == Reaction(s) known to produce the compound == | | == Reaction(s) known to produce the compound == |
| − | * [[RXN-16081]] | + | * [[RXN66-181]] |
| − | * [[RXN-17010]]
| + | |
| − | * [[RXN1G-368]]
| + | |
| − | * [[RXN-16082]]
| + | |
| − | * [[NARINGENIN-CHALCONE-SYNTHASE-RXN]]
| + | |
| − | * [[RXN-17019]]
| + | |
| − | * [[7KAPSYN-RXN]]
| + | |
| − | * [[RXN-16118]]
| + | |
| − | * [[R08184]]
| + | |
| − | * [[RXN-1106]]
| + | |
| − | * [[RXN-7645]]
| + | |
| − | * [[RXN-1101]]
| + | |
| − | * [[RXN-16042]]
| + | |
| − | * [[RXN-9654]]
| + | |
| − | * [[RXN-10821]]
| + | |
| − | * [[RXN-16152]]
| + | |
| − | * [[3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN]]
| + | |
| − | * [[RXN-9632]]
| + | |
| − | * [[RXN-13322]]
| + | |
| − | * [[RXN-12565]]
| + | |
| − | * [[RXN-9653]]
| + | |
| − | * [[RXN-9652]]
| + | |
| − | * [[RXN-9651]]
| + | |
| − | * [[RXN-9650]]
| + | |
| − | * [[RXN-13442]]
| + | |
| − | * [[2-ISOPROPYLMALATESYN-RXN]]
| + | |
| − | * [[RXN-16044]]
| + | |
| − | * [[DEPHOSPHOCOAKIN-RXN]]
| + | |
| − | * [[RXN-17021]]
| + | |
| − | * [[RXN-17729]]
| + | |
| − | * [[RXN-17023]]
| + | |
| − | * [[RXN-10662]]
| + | |
| − | * [[DIACYLGLYCEROL-O-ACYLTRANSFERASE-RXN]]
| + | |
| − | * [[RXN1G-499]]
| + | |
| − | * [[RXN-17011]]
| + | |
| − | * [[RXN1G-445]]
| + | |
| − | * [[RXN-16079]]
| + | |
| − | * [[RXN-16094]]
| + | |
| − | * [[RXN-16016]]
| + | |
| − | * [[RXN-10059]]
| + | |
| − | * [[RXN-17008]]
| + | |
| − | * [[RXN-17009]]
| + | |
| − | * [[RXN-16032]]
| + | |
| − | * [[RXN-13295]]
| + | |
| − | * [[CITSYN-RXN]]
| + | |
| − | * [[RXN-16117]]
| + | |
| − | * [[MALSYN-RXN]]
| + | |
| − | * [[RXN-1381]]
| + | |
| − | * [[RXN-3142]]
| + | |
| − | * [[RXN-15044]]
| + | |
| − | * [[RXN-15045]]
| + | |
| − | * [[RXN-9648]]
| + | |
| − | * [[RXN-15043]]
| + | |
| − | * [[RXN0-6948]]
| + | |
| − | * [[GLUCOSAMINEPNACETYLTRANS-RXN]]
| + | |
| − | * [[RXN-1623]]
| + | |
| − | * [[RXN0-1133]]
| + | |
| − | * [[LINOLEOYL-RXN]]
| + | |
| − | * [[SERINE-C-PALMITOYLTRANSFERASE-RXN]]
| + | |
| − | * [[HOMSUCTRAN-RXN]]
| + | |
| − | * [[RXN-10734]]
| + | |
| − | * [[RXN-13435]]
| + | |
| − | * [[SERINE-O-ACETTRAN-RXN]]
| + | |
| − | * [[RXN-13431]]
| + | |
| − | * [[RXN-9629]]
| + | |
| | == Reaction(s) of unknown directionality == | | == Reaction(s) of unknown directionality == |
| − | * [[RXN-16759]]
| |
| − | * [[RXN-13805]]
| |
| − | * [[RXN1G-460]]
| |
| − | * [[RXN-1124]]
| |
| − | * [[MALONYL-COA-ACP-TRANSACYL-RXN]]
| |
| − | * [[RXN-8032]]
| |
| − | * [[RXN-16103]]
| |
| − | * [[RXN-10994]]
| |
| − | * [[RXN-16415]]
| |
| − | * [[SUCCINATE--COA-LIGASE-GDP-FORMING-RXN]]
| |
| − | * [[2.3.1.97-RXN]]
| |
| − | * [[1.1.1.34-RXN]]
| |
| − | * [[FATTY-ACID-SYNTHASE-RXN]]
| |
| − | * [[HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN]]
| |
| − | * [[RXN-12561]]
| |
| − | * [[RXN-15036]]
| |
| − | * [[ISOVALERYLCOA-DHLIPOAMIDE-RXN]]
| |
| − | * [[2KETO-3METHYLVALERATE-RXN]]
| |
| − | * [[HISTONE-ACETYLTRANSFERASE-RXN]]
| |
| − | * [[RXN-14274]]
| |
| − | * [[RXN-16151]]
| |
| − | * [[PYRUFLAVREDUCT-RXN]]
| |
| − | * [[RXN-16158]]
| |
| − | * [[RXN-17688]]
| |
| − | * [[RXN0-1147]]
| |
| − | * [[MBCOA-DHLIPOAMIDE-RXN]]
| |
| − | * [[FATTY-ACYL-COA-SYNTHASE-RXN]]
| |
| − | * [[R08190]]
| |
| − | * [[RXN-16150]]
| |
| − | * [[RXN-16157]]
| |
| − | * [[ACETYL-COA-ACETYLTRANSFER-RXN]]
| |
| − | * [[RXN-16066]]
| |
| − | * [[2.3.1.23-RXN]]
| |
| − | * [[RXN-10811]]
| |
| − | * [[SUCCCOASYN-RXN]]
| |
| − | * [[RXN-13112]]
| |
| − | * [[2.3.1.168-RXN]]
| |
| − | * [[METHYLACETOACETYLCOATHIOL-RXN]]
| |
| − | * [[N-ACETYLTRANSFER-RXN]]
| |
| − | * [[ACP-S-ACETYLTRANSFER-RXN]]
| |
| − | * [[RXN-15066]]
| |
| − | * [[LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN]]
| |
| − | * [[RXN-9670]]
| |
| − | * [[RXN-14277]]
| |
| | == External links == | | == External links == |
| − | * CAS : 85-61-0
| |
| − | * Wikipedia : Coenzyme_a
| |
| − | * BIGG : 33502
| |
| | * PUBCHEM: | | * PUBCHEM: |
| − | ** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=25113190 25113190] | + | ** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=25202442 25202442] |
| − | * KNAPSACK : C00007258
| + | * HMDB : HMDB12235 |
| − | * HMDB : HMDB01423 | + | {{#set: smiles=CC([N+]C(C)(C)CO)C(=O)C1(C=CC=C(Cl)C=1)}} |
| − | * LIGAND-CPD:
| + | {{#set: inchi key=InChIKey=AKOAEVOSDHIVFX-UHFFFAOYSA-O}} |
| − | ** [http://www.genome.jp/dbget-bin/www_bget?C00010 C00010]
| + | {{#set: common name=hydroxybupropion}} |
| − | * CHEBI:
| + | {{#set: molecular weight=256.752 }} |
| − | ** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57287 57287]
| + | {{#set: produced by=RXN66-181}} |
| − | * METABOLIGHTS : MTBLC57287
| + | |
| − | {{#set: smiles=CC(C)(C(O)C(=O)NCCC(=O)NCCS)COP(=O)(OP(=O)(OCC1(OC(C(C1OP([O-])(=O)[O-])O)N3(C2(=C(C(N)=NC=N2)N=C3))))[O-])[O-]}} | + | |
| − | {{#set: inchi key=InChIKey=RGJOEKWQDUBAIZ-IBOSZNHHSA-J}} | + | |
| − | {{#set: common name=coenzyme A}} | + | |
| − | {{#set: molecular weight=763.502 }} | + | |
| − | {{#set: common name=CoA|co-A-SH|co-enzyme-A|co-A|HS-CoA}} | + | |
| − | {{#set: consumed by=RXN-2006|RXN66-483|RXN66-480|RXN0-7248|RXN66-469|RXN66-484|RXN-16418|RXN-17116|RXN-1126|2.3.1.176-RXN|RXN-14268|RXN-16045|RXN-15889|RXN-2001|RXN-16389|RXN-16041|ACYLCOASYN-RXN|RXN-16043|RXN-11921|RXN-16380|RXN-10919|RXN-13617|ACETATE--COA-LIGASE-RXN|RXN-9673|ACETOACETATE--COA-LIGASE-RXN|RXN-8988|PYRUVDEH-RXN|ATP-CITRATE-PRO-S--LYASE-RXN|RXN-13614|RXN-16137|RXN-11213|2OXOGLUTARATEDEH-RXN|RXN-7904|2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN|TRANS-RXN0-623|RXN-12978|RXN66-477|HOLO-ACP-SYNTH-RXN|RXN-12184|RXN0-7238|RXN-13290|LINOLENOYL-RXN|RXN0-7239|RXN-16393|RXN66-474|R223-RXN|RXN-2902|RXN-11917|RXN-9644|RXN-16401|1.2.1.27-RXN|PYFLAVOXRE-RXN|RXN-7790|6.2.1.34-RXN|2-KETO-ADIPATE-DEHYDROG-RXN|RXN-9623|ENTDB-RXN|4-COUMARATE--COA-LIGASE-RXN|1.2.1.25-RXN|RXN-16402}}
| + | |
| − | {{#set: produced by=RXN-16081|RXN-17010|RXN1G-368|RXN-16082|NARINGENIN-CHALCONE-SYNTHASE-RXN|RXN-17019|7KAPSYN-RXN|RXN-16118|R08184|RXN-1106|RXN-7645|RXN-1101|RXN-16042|RXN-9654|RXN-10821|RXN-16152|3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN|RXN-9632|RXN-13322|RXN-12565|RXN-9653|RXN-9652|RXN-9651|RXN-9650|RXN-13442|2-ISOPROPYLMALATESYN-RXN|RXN-16044|DEPHOSPHOCOAKIN-RXN|RXN-17021|RXN-17729|RXN-17023|RXN-10662|DIACYLGLYCEROL-O-ACYLTRANSFERASE-RXN|RXN1G-499|RXN-17011|RXN1G-445|RXN-16079|RXN-16094|RXN-16016|RXN-10059|RXN-17008|RXN-17009|RXN-16032|RXN-13295|CITSYN-RXN|RXN-16117|MALSYN-RXN|RXN-1381|RXN-3142|RXN-15044|RXN-15045|RXN-9648|RXN-15043|RXN0-6948|GLUCOSAMINEPNACETYLTRANS-RXN|RXN-1623|RXN0-1133|LINOLEOYL-RXN|SERINE-C-PALMITOYLTRANSFERASE-RXN|HOMSUCTRAN-RXN|RXN-10734|RXN-13435|SERINE-O-ACETTRAN-RXN|RXN-13431|RXN-9629}}
| + | |
| − | {{#set: reversible reaction associated=RXN-16759|RXN-13805|RXN1G-460|RXN-1124|MALONYL-COA-ACP-TRANSACYL-RXN|RXN-8032|RXN-16103|RXN-10994|RXN-16415|SUCCINATE--COA-LIGASE-GDP-FORMING-RXN|2.3.1.97-RXN|1.1.1.34-RXN|FATTY-ACID-SYNTHASE-RXN|HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN|RXN-12561|RXN-15036|ISOVALERYLCOA-DHLIPOAMIDE-RXN|2KETO-3METHYLVALERATE-RXN|HISTONE-ACETYLTRANSFERASE-RXN|RXN-14274|RXN-16151|PYRUFLAVREDUCT-RXN|RXN-16158|RXN-17688|RXN0-1147|MBCOA-DHLIPOAMIDE-RXN|FATTY-ACYL-COA-SYNTHASE-RXN|R08190|RXN-16150|RXN-16157|ACETYL-COA-ACETYLTRANSFER-RXN|RXN-16066|2.3.1.23-RXN|RXN-10811|SUCCCOASYN-RXN|RXN-13112|2.3.1.168-RXN|METHYLACETOACETYLCOATHIOL-RXN|N-ACETYLTRANSFER-RXN|ACP-S-ACETYLTRANSFER-RXN|RXN-15066|LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN|RXN-9670|RXN-14277}}
| + | |
