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| Line 1: |
Line 1: |
| − | [[Category:Metabolite]] | + | [[Category:Pathway]] |
| − | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=PPI PPI] == | + | == Pathway [http://metacyc.org/META/NEW-IMAGE?object=PWY-6627 PWY-6627] == |
| − | * smiles: | + | * taxonomic range: |
| − | ** O=P(O)(OP([O-])([O-])=O)[O-] | + | ** [http://metacyc.org/META/NEW-IMAGE?object=TAX-201174 TAX-201174] |
| − | * inchi key:
| + | |
| − | ** InChIKey=XPPKVPWEQAFLFU-UHFFFAOYSA-K
| + | |
| | * common name: | | * common name: |
| − | ** diphosphate | + | ** salinosporamide A biosynthesis |
| − | * molecular weight:
| + | |
| − | ** 174.951
| + | |
| | * Synonym(s): | | * Synonym(s): |
| − | ** PPi
| |
| − | ** PP
| |
| − | ** pyrophosphate
| |
| | | | |
| − | == Reaction(s) known to consume the compound == | + | == Reaction(s) found == |
| − | * [[INORGPYROPHOSPHAT-RXN]]
| + | '''2''' reactions found over '''15''' reactions in the full pathway |
| − | == Reaction(s) known to produce the compound ==
| + | * [[CHORISMATEMUT-RXN]] |
| − | * [[ARGININE--TRNA-LIGASE-RXN]] | + | ** 2 associated gene(s): |
| − | * [[RXN66-483]] | + | *** [[Ec-01_007700]] |
| − | * [[RXN66-480]] | + | *** [[Ec-27_003130]] |
| − | * [[RXN0-7248]] | + | ** 2 reconstruction source(s) associated: |
| − | * [[RXN66-484]] | + | *** [[annotation-esiliculosus_genome]] |
| − | * [[RXN0-2023]] | + | *** [[orthology-aragem]] |
| − | * [[GMP-SYN-GLUT-RXN]] | + | * [[RXN-11717]] |
| − | * [[ACYLCOASYN-RXN]] | + | ** 1 associated gene(s): |
| − | * [[2.7.7.30-RXN]] | + | *** [[Ec-03_000220]] |
| − | * [[ACETATE--COA-LIGASE-RXN]] | + | ** 1 reconstruction source(s) associated: |
| − | * [[RXN-1961]] | + | *** [[annotation-esiliculosus_genome]] |
| − | * [[ASPARTATE--TRNA-LIGASE-RXN]]
| + | == Reaction(s) not found == |
| − | * [[2.5.1.32-RXN]]
| + | * [http://metacyc.org/META/NEW-IMAGE?object=RXN-11712 RXN-11712] |
| − | * [[THI-P-SYN-RXN]] | + | * [http://metacyc.org/META/NEW-IMAGE?object=RXN-11713 RXN-11713] |
| − | * [[ASNSYNB-RXN]] | + | * [http://metacyc.org/META/NEW-IMAGE?object=RXN-11714 RXN-11714] |
| − | * [[HISTPRATPHYD-RXN]] | + | * [http://metacyc.org/META/NEW-IMAGE?object=RXN-11715 RXN-11715] |
| − | * [[URACIL-PRIBOSYLTRANS-RXN]] | + | * [http://metacyc.org/META/NEW-IMAGE?object=RXN-11716 RXN-11716] |
| − | * [[VALINE--TRNA-LIGASE-RXN]] | + | * [http://metacyc.org/META/NEW-IMAGE?object=RXN-11718 RXN-11718] |
| − | * [[TRYPTOPHAN--TRNA-LIGASE-RXN]] | + | * [http://metacyc.org/META/NEW-IMAGE?object=RXN-11719 RXN-11719] |
| − | * [[RXN-7904]] | + | * [http://metacyc.org/META/NEW-IMAGE?object=RXN-11720 RXN-11720] |
| − | * [[RXN-16418]] | + | * [http://metacyc.org/META/NEW-IMAGE?object=RXN-11721 RXN-11721] |
| − | * [[TRANS-OCTAPRENYLTRANSTRANSFERASE-RXN]] | + | * [http://metacyc.org/META/NEW-IMAGE?object=RXN-11722 RXN-11722] |
| − | * [[6.1.1.24-RXN]]
| + | * [http://metacyc.org/META/NEW-IMAGE?object=RXN-11723 RXN-11723] |
| − | * [[ASNSYNA-RXN]] | + | * [http://metacyc.org/META/NEW-IMAGE?object=RXN-11724 RXN-11724] |
| − | * [[DNA-LIGASE-ATP-RXN]] | + | * [http://metacyc.org/META/NEW-IMAGE?object=RXN-11725 RXN-11725] |
| − | * [[LYSINE--TRNA-LIGASE-RXN]] | + | |
| − | * [[RXN-8340]] | + | |
| − | * [[UBIQUITIN--PROTEIN-LIGASE-RXN]] | + | |
| − | * [[RXN-7810]] | + | |
| − | * [[S-ADENMETSYN-RXN]] | + | |
| − | * [[PANTEPADENYLYLTRAN-RXN]] | + | |
| − | * [[RXN-9230]]
| + | |
| − | * [[RXN-14139]] | + | |
| − | * [[RXN-9386]]
| + | |
| − | * [[R223-RXN]]
| + | |
| − | * [[RXN-9623]]
| + | |
| − | * [[2.5.1.41-RXN]] | + | |
| − | * [[2.5.1.39-RXN]]
| + | |
| − | * [[4-COUMARATE--COA-LIGASE-RXN]]
| + | |
| − | * [[NAD-SYNTH-GLN-RXN]] | + | |
| − | * [[ASPARAGINE--TRNA-LIGASE-RXN]]
| + | |
| − | * [[GLUTAMINE--TRNA-LIGASE-RXN]]
| + | |
| − | * [[6.3.4.10-RXN]] | + | |
| − | * [[ARGSUCCINSYN-RXN]]
| + | |
| − | * [[RXN-2001]]
| + | |
| − | * [[RXN0-1602]] | + | |
| − | * [[THREONINE--TRNA-LIGASE-RXN]]
| + | |
| − | * [[RXN-9003]]
| + | |
| − | * [[METHIONINE--TRNA-LIGASE-RXN]]
| + | |
| − | * [[GMP-SYN-NH3-RXN]]
| + | |
| − | * [[ISOLEUCINE--TRNA-LIGASE-RXN]] | + | |
| − | * [[RXN66-281]]
| + | |
| − | * [[NICONUCADENYLYLTRAN-RXN]]
| + | |
| − | * [[2.7.7.15-RXN]]
| + | |
| − | * [[RXN-4305]]
| + | |
| − | * [[FADSYN-RXN]]
| + | |
| − | * [[RXN-17573]]
| + | |
| − | * [[ALANINE--TRNA-LIGASE-RXN]] | + | |
| − | * [[RXN-14140]]
| + | |
| − | * [[DNA-DIRECTED-DNA-POLYMERASE-RXN]]
| + | |
| − | * [[RXN0-7239]]
| + | |
| − | * [[4OHBENZOATE-OCTAPRENYLTRANSFER-RXN]]
| + | |
| − | * [[RXN-9644]]
| + | |
| − | * [[GSADENYLATION-RXN]]
| + | |
| − | * [[RXN0-7238]]
| + | |
| − | * [[RXN-12720]]
| + | |
| − | * [[RXN-9222]]
| + | |
| − | * [[RXN-13724]]
| + | |
| − | * [[ADENYLATECYC-RXN]]
| + | |
| − | * [[PROLINE--TRNA-LIGASE-RXN]]
| + | |
| − | * [[NAD-SYNTH-NH3-RXN]]
| + | |
| − | * [[2.7.7.14-RXN]]
| + | |
| − | * [[QUINOPRIBOTRANS-RXN]]
| + | |
| − | * [[RXN-8344]]
| + | |
| − | * [[RXN-1126]] | + | |
| − | * [[RXN-7813]]
| + | |
| − | * [[RXN-7811]]
| + | |
| − | * [[RXN-10919]]
| + | |
| − | * [[RXN-16165]]
| + | |
| − | * [[H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN]]
| + | |
| − | * [[FPPSYN-RXN]]
| + | |
| − | * [[6.2.1.34-RXN]]
| + | |
| − | * [[RXN0-5359]]
| + | |
| − | * [[RXN-12056]]
| + | |
| − | * [[FARNESYLTRANSTRANSFERASE-RXN]] | + | |
| − | * [[RXN66-477]]
| + | |
| − | * [[HISTIDINE--TRNA-LIGASE-RXN]]
| + | |
| − | * [[RXN66-474]]
| + | |
| − | * [[RXN-12184]]
| + | |
| − | * [[RXN-13290]]
| + | |
| − | * [[RNA-LIGASE-ATP-RXN]]
| + | |
| − | * [[TYROSINE--TRNA-LIGASE-RXN]]
| + | |
| − | * [[MRNA-GUANYLYLTRANSFERASE-RXN]]
| + | |
| − | * [[RXN1G-121]]
| + | |
| − | * [[RXN-16393]]
| + | |
| − | * [[RXN-12263]]
| + | |
| − | * [[GTP-CYCLOHYDRO-II-RXN]]
| + | |
| − | * [[TRANS-RXN0-623]]
| + | |
| − | * [[H2PTEROATESYNTH-RXN]]
| + | |
| − | * [[RXN0-1603]]
| + | |
| − | * [[RXN0-5515]]
| + | |
| − | * [[RXN-8999]]
| + | |
| − | * [[RXN-16389]]
| + | |
| − | * [[RXN-11361]]
| + | |
| − | * [[NAG1P-URIDYLTRANS-RXN]]
| + | |
| − | * [[RXNARA-8002]]
| + | |
| − | * [[RXN-16401]]
| + | |
| − | * [[RXN-16402]]
| + | |
| − | * [[PYRUVATEORTHOPHOSPHATE-DIKINASE-RXN]]
| + | |
| − | * [[RXN66-469]]
| + | |
| − | * [[SERINE--TRNA-LIGASE-RXN]]
| + | |
| − | * [[LINOLENOYL-RXN]]
| + | |
| − | * [[PANTOATE-BETA-ALANINE-LIG-RXN]]
| + | |
| − | * [[2.7.7.60-RXN]]
| + | |
| − | * [[RXN0-7192]]
| + | |
| − | * [[RXN-16380]]
| + | |
| − | * [[RNA-3-PHOSPHATE-CYCLASE-RXN]] | + | |
| − | * [[RXN-13162]]
| + | |
| − | * [[ADENPRIBOSYLTRAN-RXN]]
| + | |
| − | * [[RXN-9673]]
| + | |
| − | * [[ACETOACETATE--COA-LIGASE-RXN]]
| + | |
| − | * [[RXN-11486]]
| + | |
| − | * [[CYSTEINE--TRNA-LIGASE-RXN]]
| + | |
| − | * [[6.3.4.11-RXN]]
| + | |
| − | * [[LEUCINE--TRNA-LIGASE-RXN]]
| + | |
| − | * [[RXN-13614]]
| + | |
| − | * [[GLYCINE--TRNA-LIGASE-RXN]] | + | |
| − | * [[PHENYLALANINE--TRNA-LIGASE-RXN]]
| + | |
| − | * [[CDPDIGLYSYN-RXN]]
| + | |
| − | * [[RXN-10]]
| + | |
| − | * [[2.7.7.13-RXN]]
| + | |
| − | * [[NICOTINATEPRIBOSYLTRANS-RXN]]
| + | |
| − | * [[RXN-12978]]
| + | |
| − | * [[RXN-2541]] | + | |
| − | * [[RXN-4303]]
| + | |
| − | * [[6.3.4.9-RXN]]
| + | |
| − | * [[BIOTINLIG-RXN]]
| + | |
| − | * [[RXN0-2161]]
| + | |
| − | * [[GLURS-RXN]]
| + | |
| − | * [[RXN0-6382]]
| + | |
| − | * [[DUTP-PYROP-RXN]]
| + | |
| − | * [[RXN0-385]]
| + | |
| − | * [[RXN0-6274]]
| + | |
| − | == Reaction(s) of unknown directionality == | + | |
| − | * [[RXN1F-144]]
| + | |
| − | * [[RNA-DIRECTED-DNA-POLYMERASE-RXN]]
| + | |
| − | * [[ATPPHOSPHORIBOSYLTRANS-RXN]]
| + | |
| − | * [[RXN-3701]]
| + | |
| − | * [[GUANYLCYC-RXN]] | + | |
| − | * [[TCX10]]
| + | |
| − | * [[2.5.1.58-RXN]]
| + | |
| − | * [[TCM3]]
| + | |
| − | * [[RXN-13323]]
| + | |
| − | * [[OROPRIBTRANS-RXN]]
| + | |
| − | * [[RXN-12503]]
| + | |
| − | * [[TCP26]]
| + | |
| − | * [[SULFATE-ADENYLYLTRANS-RXN]]
| + | |
| − | * [[RXN0-5180]]
| + | |
| − | * [[RXN-14270]]
| + | |
| − | * [[RXN-16415]]
| + | |
| − | * [[HYPOXANPRIBOSYLTRAN-RXN]]
| + | |
| − | * [[RNA-DIRECTED-RNA-POLYMERASE-RXN]]
| + | |
| − | * [[PRTRANS-RXN]]
| + | |
| − | * [[PRPPAMIDOTRANS-RXN]]
| + | |
| − | * [[DNA-DIRECTED-RNA-POLYMERASE-RXN]]
| + | |
| − | * [[RXN-11368]]
| + | |
| − | * [[GUANPRIBOSYLTRAN-RXN]]
| + | |
| − | * [[GLUC1PURIDYLTRANS-RXN]]
| + | |
| − | * [[RXN-14569]]
| + | |
| − | * [[GPPSYN-RXN]]
| + | |
| − | * [[POLYNUCLEOTIDE-ADENYLYLTRANSFERASE-RXN]]
| + | |
| − | * [[RXN-12502]]
| + | |
| | == External links == | | == External links == |
| − | * CAS : 2466-09-3
| + | {{#set: taxonomic range=TAX-201174}} |
| − | * BIGG : 33511
| + | {{#set: common name=salinosporamide A biosynthesis}} |
| − | * DRUGBANK : DB04160
| + | {{#set: reaction found=2}} |
| − | * PUBCHEM:
| + | {{#set: total reaction=15}} |
| − | ** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=1023 1023]
| + | {{#set: completion rate=13.0}} |
| − | * HMDB : HMDB00250
| + | |
| − | * LIGAND-CPD:
| + | |
| − | ** [http://www.genome.jp/dbget-bin/www_bget?C00013 C00013]
| + | |
| − | * CHEMSPIDER:
| + | |
| − | ** [http://www.chemspider.com/Chemical-Structure.996.html 996]
| + | |
| − | * CHEBI:
| + | |
| − | ** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=29888 29888]
| + | |
| − | * METABOLIGHTS : MTBLC33019
| + | |
| − | {{#set: smiles=O=P(O)(OP([O-])([O-])=O)[O-]}} | + | |
| − | {{#set: inchi key=InChIKey=XPPKVPWEQAFLFU-UHFFFAOYSA-K}}
| + | |
| − | {{#set: common name=diphosphate}} | + | |
| − | {{#set: molecular weight=174.951 }} | + | |
| − | {{#set: common name=PPi|PP|pyrophosphate}} | + | |
| − | {{#set: consumed by=INORGPYROPHOSPHAT-RXN}} | + | |
| − | {{#set: produced by=ARGININE--TRNA-LIGASE-RXN|RXN66-483|RXN66-480|RXN0-7248|RXN66-484|RXN0-2023|GMP-SYN-GLUT-RXN|ACYLCOASYN-RXN|2.7.7.30-RXN|ACETATE--COA-LIGASE-RXN|RXN-1961|ASPARTATE--TRNA-LIGASE-RXN|2.5.1.32-RXN|THI-P-SYN-RXN|ASNSYNB-RXN|HISTPRATPHYD-RXN|URACIL-PRIBOSYLTRANS-RXN|VALINE--TRNA-LIGASE-RXN|TRYPTOPHAN--TRNA-LIGASE-RXN|RXN-7904|RXN-16418|TRANS-OCTAPRENYLTRANSTRANSFERASE-RXN|6.1.1.24-RXN|ASNSYNA-RXN|DNA-LIGASE-ATP-RXN|LYSINE--TRNA-LIGASE-RXN|RXN-8340|UBIQUITIN--PROTEIN-LIGASE-RXN|RXN-7810|S-ADENMETSYN-RXN|PANTEPADENYLYLTRAN-RXN|RXN-9230|RXN-14139|RXN-9386|R223-RXN|RXN-9623|2.5.1.41-RXN|2.5.1.39-RXN|4-COUMARATE--COA-LIGASE-RXN|NAD-SYNTH-GLN-RXN|ASPARAGINE--TRNA-LIGASE-RXN|GLUTAMINE--TRNA-LIGASE-RXN|6.3.4.10-RXN|ARGSUCCINSYN-RXN|RXN-2001|RXN0-1602|THREONINE--TRNA-LIGASE-RXN|RXN-9003|METHIONINE--TRNA-LIGASE-RXN|GMP-SYN-NH3-RXN|ISOLEUCINE--TRNA-LIGASE-RXN|RXN66-281|NICONUCADENYLYLTRAN-RXN|2.7.7.15-RXN|RXN-4305|FADSYN-RXN|RXN-17573|ALANINE--TRNA-LIGASE-RXN|RXN-14140|DNA-DIRECTED-DNA-POLYMERASE-RXN|RXN0-7239|4OHBENZOATE-OCTAPRENYLTRANSFER-RXN|RXN-9644|GSADENYLATION-RXN|RXN0-7238|RXN-12720|RXN-9222|RXN-13724|ADENYLATECYC-RXN|PROLINE--TRNA-LIGASE-RXN|NAD-SYNTH-NH3-RXN|2.7.7.14-RXN|QUINOPRIBOTRANS-RXN|RXN-8344|RXN-1126|RXN-7813|RXN-7811|RXN-10919|RXN-16165|H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN|FPPSYN-RXN|6.2.1.34-RXN|RXN0-5359|RXN-12056|FARNESYLTRANSTRANSFERASE-RXN|RXN66-477|HISTIDINE--TRNA-LIGASE-RXN|RXN66-474|RXN-12184|RXN-13290|RNA-LIGASE-ATP-RXN|TYROSINE--TRNA-LIGASE-RXN|MRNA-GUANYLYLTRANSFERASE-RXN|RXN1G-121|RXN-16393|RXN-12263|GTP-CYCLOHYDRO-II-RXN|TRANS-RXN0-623|H2PTEROATESYNTH-RXN|RXN0-1603|RXN0-5515|RXN-8999|RXN-16389|RXN-11361|NAG1P-URIDYLTRANS-RXN|RXNARA-8002|RXN-16401|RXN-16402|PYRUVATEORTHOPHOSPHATE-DIKINASE-RXN|RXN66-469|SERINE--TRNA-LIGASE-RXN|LINOLENOYL-RXN|PANTOATE-BETA-ALANINE-LIG-RXN|2.7.7.60-RXN|RXN0-7192|RXN-16380|RNA-3-PHOSPHATE-CYCLASE-RXN|RXN-13162|ADENPRIBOSYLTRAN-RXN|RXN-9673|ACETOACETATE--COA-LIGASE-RXN|RXN-11486|CYSTEINE--TRNA-LIGASE-RXN|6.3.4.11-RXN|LEUCINE--TRNA-LIGASE-RXN|RXN-13614|GLYCINE--TRNA-LIGASE-RXN|PHENYLALANINE--TRNA-LIGASE-RXN|CDPDIGLYSYN-RXN|RXN-10|2.7.7.13-RXN|NICOTINATEPRIBOSYLTRANS-RXN|RXN-12978|RXN-2541|RXN-4303|6.3.4.9-RXN|BIOTINLIG-RXN|RXN0-2161|GLURS-RXN|RXN0-6382|DUTP-PYROP-RXN|RXN0-385|RXN0-6274}}
| + | |
| − | {{#set: reversible reaction associated=RXN1F-144|RNA-DIRECTED-DNA-POLYMERASE-RXN|ATPPHOSPHORIBOSYLTRANS-RXN|RXN-3701|GUANYLCYC-RXN|TCX10|2.5.1.58-RXN|TCM3|RXN-13323|OROPRIBTRANS-RXN|RXN-12503|TCP26|SULFATE-ADENYLYLTRANS-RXN|RXN0-5180|RXN-14270|RXN-16415|HYPOXANPRIBOSYLTRAN-RXN|RNA-DIRECTED-RNA-POLYMERASE-RXN|PRTRANS-RXN|PRPPAMIDOTRANS-RXN|DNA-DIRECTED-RNA-POLYMERASE-RXN|RXN-11368|GUANPRIBOSYLTRAN-RXN|GLUC1PURIDYLTRANS-RXN|RXN-14569|GPPSYN-RXN|POLYNUCLEOTIDE-ADENYLYLTRANSFERASE-RXN|RXN-12502}}
| + | |
