Difference between revisions of "METHYLENE-THF"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLUTAMATE-SYNTHASE-FERREDOXIN-RXN GLUTAMATE-SYNTHASE-FERREDOXIN-RXN] == * direction: ** LEFT-TO-RIG...")
(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=METHYLENE-THF METHYLENE-THF] == * smiles: ** C4(NC1(N=C(N)NC(=O)C=1N3(CN(C2(=CC=C(C=C2)C(=O)NC(...")
 
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[[Category:Reaction]]
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[[Category:Metabolite]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLUTAMATE-SYNTHASE-FERREDOXIN-RXN GLUTAMATE-SYNTHASE-FERREDOXIN-RXN] ==
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=METHYLENE-THF METHYLENE-THF] ==
* direction:
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* smiles:
** LEFT-TO-RIGHT
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** C4(NC1(N=C(N)NC(=O)C=1N3(CN(C2(=CC=C(C=C2)C(=O)NC(CCC([O-])=O)C([O-])=O))C[CH]34)))
 
* common name:
 
* common name:
** Glutamate synthase (ferredoxin-dependent)
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** 5,10-methylenetetrahydropteroyl mono-L-glutamate
** Aldolase-type TIM barrel
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* inchi key:
* ec number:
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** InChIKey=QYNUQALWYRSVHF-OLZOCXBDSA-L
** [http://enzyme.expasy.org/EC/1.4.7.1 EC-1.4.7.1]
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* molecular weight:
 +
** 455.429   
 
* Synonym(s):
 
* Synonym(s):
 +
** N5,N10-methylenetetrahydrofolate mono-L-glutamate
 +
** 5,10-methylenetetrahydrofolate mono-L-glutamate
 +
** 5,10-methylene-H4PteGlu1
  
== Reaction Formula ==
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== Reaction(s) known to consume the compound ==
* With identifiers:
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* [[1.5.1.20-RXN-5-METHYL-THF/NAD//METHYLENE-THF/NADH/PROTON.44.]]
** 2 [[PROTON]][c] '''+''' 1 [[GLN]][c] '''+''' 2 [[Reduced-ferredoxins]][c] '''+''' 1 [[2-KETOGLUTARATE]][c] '''=>''' 2 [[Oxidized-ferredoxins]][c] '''+''' 2 [[GLT]][c]
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== Reaction(s) known to produce the compound ==
* With common name(s):
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== Reaction(s) of unknown directionality ==
** 2 H+[c] '''+''' 1 L-glutamine[c] '''+''' 2 a reduced ferredoxin [iron-sulfur] cluster[c] '''+''' 1 2-oxoglutarate[c] '''=>''' 2 an oxidized ferredoxin [iron-sulfur] cluster[c] '''+''' 2 L-glutamate[c]
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* [[GLYOHMETRANS-RXN-SER/THF//GLY/METHYLENE-THF/WATER.33.]]
 
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* [[GCVMULTI-RXN-GLY/THF/NAD//METHYLENE-THF/AMMONIUM/CARBON-DIOXIDE/NADH.56.]]
== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[Ec-00_000720]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Assignment: EC-NUMBER
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* Gene: [[Ec-26_004630]]
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** Source: [[orthology-aragem]]
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* Gene: [[Ec-27_004970]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Assignment: EC-NUMBER
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** Source: [[orthology-aragem]]
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== Pathways  ==
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* [[PWY-6964]], ammonia assimilation cycle II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6964 PWY-6964]
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** '''2''' reactions found over '''2''' reactions in the full pathway
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* [[PWY-4341]], L-glutamate biosynthesis V: [http://metacyc.org/META/NEW-IMAGE?object=PWY-4341 PWY-4341]
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** '''1''' reactions found over '''1''' reactions in the full pathway
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* [[PWY-6549]], L-glutamine biosynthesis III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6549 PWY-6549]
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** '''8''' reactions found over '''9''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[orthology]]
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** Source: [[orthology-aragem]]
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*** Tool: [[pantograph]]
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* Category: [[annotation]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Tool: [[pathwaytools]]
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== External links  ==
 
== External links  ==
* LIGAND-RXN:
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* METABOLIGHTS : MTBLC15636
** [http://www.genome.jp/dbget-bin/www_bget?R00021 R00021]
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* PUBCHEM:
* UNIPROT:
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=9548565 9548565]
** [http://www.uniprot.org/uniprot/P23225 P23225]
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* HMDB : HMDB01533
** [http://www.uniprot.org/uniprot/O67512 O67512]
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* LIGAND-CPD:
** [http://www.uniprot.org/uniprot/P96218 P96218]
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** [http://www.genome.jp/dbget-bin/www_bget?C00143 C00143]
** [http://www.uniprot.org/uniprot/Q06434 Q06434]
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* CHEMSPIDER:
** [http://www.uniprot.org/uniprot/Q43081 Q43081]
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** [http://www.chemspider.com/Chemical-Structure.7827491.html 7827491]
** [http://www.uniprot.org/uniprot/P55037 P55037]
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* CHEBI:
** [http://www.uniprot.org/uniprot/Q43155 Q43155]
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=15636 15636]
** [http://www.uniprot.org/uniprot/Q7M242 Q7M242]
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* BIGG : 34022
** [http://www.uniprot.org/uniprot/P51375 P51375]
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{{#set: smiles=C4(NC1(N=C(N)NC(=O)C=1N3(CN(C2(=CC=C(C=C2)C(=O)NC(CCC([O-])=O)C([O-])=O))C[CH]34)))}}
** [http://www.uniprot.org/uniprot/P55038 P55038]
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{{#set: common name=5,10-methylenetetrahydropteroyl mono-L-glutamate}}
** [http://www.uniprot.org/uniprot/Q9SLM4 Q9SLM4]
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{{#set: inchi key=InChIKey=QYNUQALWYRSVHF-OLZOCXBDSA-L}}
** [http://www.uniprot.org/uniprot/Q08258 Q08258]
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{{#set: molecular weight=455.429    }}
** [http://www.uniprot.org/uniprot/O49154 O49154]
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{{#set: common name=N5,N10-methylenetetrahydrofolate mono-L-glutamate|5,10-methylenetetrahydrofolate mono-L-glutamate|5,10-methylene-H4PteGlu1}}
** [http://www.uniprot.org/uniprot/O19906 O19906]
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{{#set: consumed by=1.5.1.20-RXN-5-METHYL-THF/NAD//METHYLENE-THF/NADH/PROTON.44.}}
{{#set: direction=LEFT-TO-RIGHT}}
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{{#set: reversible reaction associated=GLYOHMETRANS-RXN-SER/THF//GLY/METHYLENE-THF/WATER.33.|GCVMULTI-RXN-GLY/THF/NAD//METHYLENE-THF/AMMONIUM/CARBON-DIOXIDE/NADH.56.}}
{{#set: common name=Glutamate synthase (ferredoxin-dependent)}}
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{{#set: common name=Aldolase-type TIM barrel}}
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{{#set: ec number=EC-1.4.7.1}}
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{{#set: gene associated=Ec-00_000720|Ec-26_004630|Ec-27_004970}}
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{{#set: in pathway=PWY-6964|PWY-4341|PWY-6549}}
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{{#set: reconstruction category=orthology|annotation}}
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{{#set: reconstruction source=annotation-esiliculosus_genome|orthology-aragem}}
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{{#set: reconstruction tool=pantograph|pathwaytools}}
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Latest revision as of 19:54, 21 March 2018

Metabolite METHYLENE-THF

  • smiles:
    • C4(NC1(N=C(N)NC(=O)C=1N3(CN(C2(=CC=C(C=C2)C(=O)NC(CCC([O-])=O)C([O-])=O))C[CH]34)))
  • common name:
    • 5,10-methylenetetrahydropteroyl mono-L-glutamate
  • inchi key:
    • InChIKey=QYNUQALWYRSVHF-OLZOCXBDSA-L
  • molecular weight:
    • 455.429
  • Synonym(s):
    • N5,N10-methylenetetrahydrofolate mono-L-glutamate
    • 5,10-methylenetetrahydrofolate mono-L-glutamate
    • 5,10-methylene-H4PteGlu1

Reaction(s) known to consume the compound

Reaction(s) known to produce the compound

Reaction(s) of unknown directionality

External links

  • METABOLIGHTS : MTBLC15636
  • PUBCHEM:
  • HMDB : HMDB01533
  • LIGAND-CPD:
  • CHEMSPIDER:
  • CHEBI:
  • BIGG : 34022
"C4(NC1(N=C(N)NC(=O)C=1N3(CN(C2(=CC=C(C=C2)C(=O)NC(CCC([O-])=O)C([O-])=O))C[CH]34)))" cannot be used as a page name in this wiki.