Difference between revisions of "CPD-504"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=OHACYL-COA-DEHYDROG-RXN OHACYL-COA-DEHYDROG-RXN] == * direction: ** LEFT-TO-RIGHT * common name: **...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-8991 RXN-8991] == * direction: ** REVERSIBLE * common name: ** 3-isopropylmalate dehydratase **...")
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=OHACYL-COA-DEHYDROG-RXN OHACYL-COA-DEHYDROG-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-8991 RXN-8991] ==
 
* direction:
 
* direction:
−
** LEFT-TO-RIGHT
+
** REVERSIBLE
 
* common name:
 
* common name:
−
** 3-hydroxyacyl-CoA dehydrogenase
+
** 3-isopropylmalate dehydratase
−
** 6-phosphogluconate dehydrogenase, C-terminal-like
+
** Aconitase/3-isopropylmalate dehydratase, swivel
−
* ec number:
+
−
** [http://enzyme.expasy.org/EC/1.1.1.35 EC-1.1.1.35]
+
 
* Synonym(s):
 
* Synonym(s):
 +
** (2R,3S)-3-isopropylmalate hydro-lyase
 +
** β-isopropylmalate dehydratase
 +
** α-isopropylmalate isomerase
 +
** 3-isopropylmalate hydro-lyase
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[NAD]][c] '''+''' 1 [[L-3-HYDROXYACYL-COA]][c] '''=>''' 1 [[PROTON]][c] '''+''' 1 [[3-KETOACYL-COA]][c] '''+''' 1 [[NADH]][c]
+
** 1 [[2-D-THREO-HYDROXY-3-CARBOXY-ISOCAPROATE]][c] '''<=>''' 1 [[WATER]][c] '''+''' 1 [[CPD-9451]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 NAD+[c] '''+''' 1 a (3S)-3-hydroxyacyl-CoA[c] '''=>''' 1 H+[c] '''+''' 1 a 3-oxoacyl-CoA[c] '''+''' 1 NADH[c]
+
** 1 (2R,3S)-3-isopropylmalate[c] '''<=>''' 1 H2O[c] '''+''' 1 2-isopropylmaleate[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* [[Ec-14_006530]]
+
* [[Ec-sdr_f_000030]]
−
** ESILICULOSUS_GENOME
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** [[pantograph]]-[[aragem]]
−
***GO-TERM
+
* [[Ec-12_000170]]
−
* [[Ec-19_005290]]
+
 
** ESILICULOSUS_GENOME
 
** ESILICULOSUS_GENOME
 
***EC-NUMBER
 
***EC-NUMBER
 +
** [[pantograph]]-[[aragem]]
 +
* [[Ec-13_001950]]
 +
** [[pantograph]]-[[aragem]]
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-5136]], fatty acid &beta;-oxidation II (peroxisome): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5136 PWY-5136]
+
* [[LEUSYN-PWY]], L-leucine biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=LEUSYN-PWY LEUSYN-PWY]
−
** '''4''' reactions found over '''5''' reactions in the full pathway
+
** '''6''' reactions found over '''6''' reactions in the full pathway
−
* [[PWY-7007]], methyl ketone biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7007 PWY-7007]
+
* [[PWY-6871]], 3-methylbutanol biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6871 PWY-6871]
−
** '''3''' reactions found over '''6''' reactions in the full pathway
+
−
* [[FAO-PWY]], fatty acid &beta;-oxidation I: [http://metacyc.org/META/NEW-IMAGE?object=FAO-PWY FAO-PWY]
+
 
** '''5''' reactions found over '''7''' reactions in the full pathway
 
** '''5''' reactions found over '''7''' reactions in the full pathway
−
* [[PWY66-391]], fatty acid &beta;-oxidation VI (peroxisome): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-391 PWY66-391]
 
−
** '''4''' reactions found over '''7''' reactions in the full pathway
 
 
== Reconstruction information  ==
 
== Reconstruction information  ==
−
* [[annotation]]:
+
* Category: [[orthology]]
−
** [[pathwaytools]]:
+
** Source: [[orthology-aragem]]
−
*** [[esiliculosus_genome]]
+
*** Tool: [[pantograph]]
 +
* Category: [[annotation]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=22432 22432]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=10676 10676]
−
* PIR:
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A39592 A39592]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A49613 A49613]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A55045 A55045]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=DEPGC DEPGC]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=DWRTEP DWRTEP]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=JC4210 JC4210]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=JC4879 JC4879]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=JX0199 JX0199]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S32607 S32607]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S36678 S36678]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S40743 S40743]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S54786 S54786]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S57651 S57651]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S74114 S74114]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T10464 T10464]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T46866 T46866]
+
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R01778 R01778]
+
** [http://www.genome.jp/dbget-bin/www_bget?R04001 R04001]
−
* UNIPROT:
+
{{#set: direction=REVERSIBLE}}
−
** [http://www.uniprot.org/uniprot/P21177 P21177]
+
{{#set: common name=3-isopropylmalate dehydratase}}
−
** [http://www.uniprot.org/uniprot/Q08426 Q08426]
+
{{#set: common name=Aconitase/3-isopropylmalate dehydratase, swivel}}
−
** [http://www.uniprot.org/uniprot/Q53924 Q53924]
+
{{#set: common name=(2R,3S)-3-isopropylmalate hydro-lyase|&beta;-isopropylmalate dehydratase|&alpha;-isopropylmalate isomerase|3-isopropylmalate hydro-lyase}}
−
** [http://www.uniprot.org/uniprot/P07896 P07896]
+
{{#set: gene associated=Ec-sdr_f_000030|Ec-12_000170|Ec-13_001950}}
−
** [http://www.uniprot.org/uniprot/Q61425 Q61425]
+
{{#set: in pathway=LEUSYN-PWY|PWY-6871}}
−
** [http://www.uniprot.org/uniprot/Q16836 Q16836]
+
{{#set: reconstruction category=orthology|annotation}}
−
** [http://www.uniprot.org/uniprot/P28793 P28793]
+
{{#set: reconstruction source=annotation-esiliculosus_genome|orthology-aragem}}
−
** [http://www.uniprot.org/uniprot/P22414 P22414]
+
{{#set: reconstruction tool=pantograph|pathwaytools}}
−
** [http://www.uniprot.org/uniprot/Q7M0E0 Q7M0E0]
+
−
** [http://www.uniprot.org/uniprot/P34439 P34439]
+
−
** [http://www.uniprot.org/uniprot/Q01373 Q01373]
+
−
** [http://www.uniprot.org/uniprot/P55100 P55100]
+
−
** [http://www.uniprot.org/uniprot/Q39659 Q39659]
+
−
** [http://www.uniprot.org/uniprot/P00348 P00348]
+
−
{{#set: direction=LEFT-TO-RIGHT}}
+
−
{{#set: common name=3-hydroxyacyl-CoA dehydrogenase}}
+
−
{{#set: common name=6-phosphogluconate dehydrogenase, C-terminal-like}}
+
−
{{#set: ec number=EC-1.1.1.35}}
+
−
{{#set: gene associated=Ec-14_006530|Ec-19_005290}}
+
−
{{#set: in pathway=PWY-5136|PWY-7007|FAO-PWY|PWY66-391}}
+
−
{{#set: reconstruction category=annotation}}
+
−
{{#set: reconstruction tool=pathwaytools}}
+
−
{{#set: reconstruction source=esiliculosus_genome}}
+

Revision as of 21:35, 17 March 2018

Reaction RXN-8991

  • direction:
    • REVERSIBLE
  • common name:
    • 3-isopropylmalate dehydratase
    • Aconitase/3-isopropylmalate dehydratase, swivel
  • Synonym(s):
    • (2R,3S)-3-isopropylmalate hydro-lyase
    • β-isopropylmalate dehydratase
    • α-isopropylmalate isomerase
    • 3-isopropylmalate hydro-lyase

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • LEUSYN-PWY, L-leucine biosynthesis: LEUSYN-PWY
    • 6 reactions found over 6 reactions in the full pathway
  • PWY-6871, 3-methylbutanol biosynthesis (engineered): PWY-6871
    • 5 reactions found over 7 reactions in the full pathway

Reconstruction information

External links





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