PWY-7401

Reaction IGPSYN-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • Aldolase-type TIM barrel
  • Indole-3-glycerol phosphate synthase
  • FIST domain, N-terminal
  • indole-3-glycerol-phosphate synthase
• ec number:
  • EC-4.1.1.48
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CARBOXYPHENYLAMINO-DEOXYRIBULOSE-P[c] + 1 PROTON[c] => 1 WATER[c] + 1 CARBON-DIOXIDE[c] + 1 INDOLE-3-GLYCEROL-P[c]
• With common name(s):
  • 1 1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate[c] + 1 H+[c] => 1 H2O[c] + 1 CO2[c] + 1 (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Ec-08_003030
  • Source: annotation-esiliculosus_genome
    • Assignment: EC-NUMBER
• Gene: Ec-03_003850
  • Source: annotation-esiliculosus_genome
    • Assignment: EC-NUMBER
• Gene: Ec-11_002820
  • Source: annotation-esiliculosus_genome
    • Assignment: EC-NUMBER
  • Source: orthology-aragem
• Gene: Ec-08_003020
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-27_004020
  • Source: annotation-esiliculosus_genome
    • Assignment: EC-NUMBER

Pathways

• TRPSYN-PWY, L-tryptophan biosynthesis: TRPSYN-PWY
  • 6 reactions found over 6 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-aragem
    • Tool: pantograph
• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 23476
• LIGAND-RXN:
  • R03508
• UNIPROT:
  • P42393
  • P20577
  • P18304
  • Q06121
  • Q9V1G3
  • P20578
  • Q9PI11
  • Q58328
  • Q9JSN4
  • P03964
  • P00910
  • P00909
  • P00911
  • P17217
  • P20409
  • P00937
  • P00908
  • P05328
  • P06531
  • P18483
  • P25170
  • P26938
  • P24773
  • Q01999
  • Q9YGB5
  • Q9S591
  • Q9X7C7
  • Q92370
  • Q9ZFA7
  • P94327