PGLYCDEHYDROG-RXN

Reaction PGLYCDEHYDROG-RXN

• direction:
  • REVERSIBLE
• common name:
  • Phosphoglycerate dehydrogenase / Phosphoserine aminotransferase
  • D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
  • Allosteric substrate binding domain
• ec number:
  • EC-1.1.1.95
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 NAD[c] + 1 G3P[c] <=> 1 3-P-HYDROXYPYRUVATE[c] + 1 PROTON[c] + 1 NADH[c]
• With common name(s):
  • 1 NAD+[c] + 1 3-phospho-D-glycerate[c] <=> 1 3-phospho-hydroxypyruvate[c] + 1 H+[c] + 1 NADH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Ec-17_000820
  • Source: annotation-esiliculosus_genome
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: Ec-04_006300
  • Source: annotation-esiliculosus_genome
    • Assignment: EC-NUMBER
  • Source: orthology-aragem
• Gene: Ec-11_000960
  • Source: annotation-esiliculosus_genome
    • Assignment: EC-NUMBER

Pathways

• SERSYN-PWY, L-serine biosynthesis: SERSYN-PWY
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-aragem
    • Tool: pantograph
• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 12641
• LIGAND-RXN:
  • R01513
• UNIPROT:
  • Q58424
  • P43885
  • P35136
  • Q9PP40
  • P0A9T0
  • P40510
  • P40054
  • O49485
  • P87228
  • O04130