PWY-1781

Reaction 2.4.1.119-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • DAD/Ost2
  • Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1
  • Oligosaccharyl transferase complex, subunit OST3/OST6
  • Ribophorin I
  • Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1
  • Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A, C-terminal fragment, family GT66
  • Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A, N-terminal fragment, family GT66
• ec number:
  • EC-2.4.99.18
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CPD-18076[c] + 1 Protein-L-Asparagine[c] => 1 CPD-224[c] + 1 CPD-18077[c] + 1 PROTON[c]
• With common name(s):
  • 1 a (glucosyl)3(mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol[c] + 1 a [protein]-L-asparagine[c] => 1 a dolichyl diphosphate[c] + 1 a [protein]-L-asparagine-[(glucosyl)3(mannosyl)9(N-acetylglucosaminyl)2][c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Ec-10_002870
  • ESILICULOSUS_GENOME
    • AUTOMATED-NAME-MATCH
• Ec-00_007060
  • ESILICULOSUS_GENOME
    • EC-NUMBER
• Ec-22_002490
  • ESILICULOSUS_GENOME
    • EC-NUMBER
• Ec-07_004230
  • ESILICULOSUS_GENOME
    • EC-NUMBER
• Ec-00_007050
  • ESILICULOSUS_GENOME
    • EC-NUMBER
• Ec-14_004370
  • ESILICULOSUS_GENOME
    • EC-NUMBER
• Ec-09_000810
  • ESILICULOSUS_GENOME
    • EC-NUMBER

Pathways

• MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS, protein N-glycosylation (eukaryotic, high mannose): MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
  • 19 reactions found over 19 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• UNIPROT:
  • P39656
  • P48440
  • P41543
  • P80896
  • P80897
  • P48439
  • P46964
  • Q92316
  • Q10176