PWY-5135

Reaction GLUTAMATE-DEHYDROGENASE-RXN

• direction:
  • REVERSIBLE
• common name:
  • Glutamate dehydrogenase (NAD-dependent)
• ec number:
  • EC-1.4.1.2
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 NAD[c] + 1 GLT[c] + 1 WATER[c] <=> 1 AMMONIUM[c] + 1 2-KETOGLUTARATE[c] + 1 NADH[c] + 1 PROTON[c]
• With common name(s):
  • 1 NAD+[c] + 1 L-glutamate[c] + 1 H2O[c] <=> 1 ammonium[c] + 1 2-oxoglutarate[c] + 1 NADH[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Ec-12_008040
  • Source: orthology-aragem
• Gene: Ec-06_008240
  • Source: orthology-aragem
• Gene: Ec-06_001980
  • Source: annotation-esiliculosus_genome
    • Assignment: EC-NUMBER

Pathways

• GLUTAMATE-DEG1-PWY, L-glutamate degradation I: GLUTAMATE-DEG1-PWY
  • 1 reactions found over 1 reactions in the full pathway
• ALACAT2-PWY, L-alanine degradation II (to D-lactate): ALACAT2-PWY
  • 2 reactions found over 3 reactions in the full pathway
• P162-PWY, L-glutamate degradation V (via hydroxyglutarate): P162-PWY
  • 4 reactions found over 11 reactions in the full pathway
• PWY-5022, 4-aminobutanoate degradation V: PWY-5022
  • 1 reactions found over 7 reactions in the full pathway
• PWY-6728, methylaspartate cycle: PWY-6728
  • 11 reactions found over 18 reactions in the full pathway
• PWY-7126, ethylene biosynthesis IV (engineered): PWY-7126
  • 1 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-aragem
    • Tool: pantograph
• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 15133
• LIGAND-RXN:
  • R00243
• UNIPROT:
  • P20016
  • P28997
  • P41755
  • Q9JTP6
  • P00365
  • P93541
  • P80319
  • P24295
  • P27346
  • P33327
  • Q43260
  • O04937
  • Q25415
  • O74024
  • O59650