RXN-14199

Reaction FUMHYDR-RXN

• direction:
  • REVERSIBLE
• common name:
  • Fumarate lyase, N-terminal
  • fumarate hydratase
• ec number:
  • EC-4.2.1.2
• Synonym(s):
  • fumarate hydration
  • malate dehydration

Reaction Formula

• With identifiers:
  • 1 MAL[c] <=> 1 FUM[c] + 1 WATER[c]
• With common name(s):
  • 1 (S)-malate[c] <=> 1 fumarate[c] + 1 H2O[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Ec-25_001360
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
• Gene: Ec-23_003460
  • Source: annotation-esiliculosus_genome
    • Assignment: EC-NUMBER
  • Source: orthology-aragem

Pathways

• PWY-561, superpathway of glyoxylate cycle and fatty acid degradation: PWY-561
  • 6 reactions found over 8 reactions in the full pathway
• PWY-5913, partial TCA cycle (obligate autotrophs): PWY-5913
  • 10 reactions found over 11 reactions in the full pathway
• P42-PWY, incomplete reductive TCA cycle: P42-PWY
  • 5 reactions found over 7 reactions in the full pathway
• PWY-7384, anaerobic energy metabolism (invertebrates, mitochondrial): PWY-7384
  • 6 reactions found over 12 reactions in the full pathway
• PWY-5392, reductive TCA cycle II: PWY-5392
  • 6 reactions found over 12 reactions in the full pathway
• TCA, TCA cycle I (prokaryotic): TCA
  • 9 reactions found over 10 reactions in the full pathway
• P23-PWY, reductive TCA cycle I: P23-PWY
  • 10 reactions found over 12 reactions in the full pathway
• P105-PWY, TCA cycle IV (2-oxoglutarate decarboxylase): P105-PWY
  • 9 reactions found over 11 reactions in the full pathway
• FERMENTATION-PWY, mixed acid fermentation: FERMENTATION-PWY
  • 8 reactions found over 16 reactions in the full pathway
• PWY-6728, methylaspartate cycle: PWY-6728
  • 11 reactions found over 18 reactions in the full pathway
• REDCITCYC, TCA cycle VIII (helicobacter): REDCITCYC
  • 5 reactions found over 9 reactions in the full pathway
• PWY-7254, TCA cycle VII (acetate-producers): PWY-7254
  • 7 reactions found over 9 reactions in the full pathway
• P108-PWY, pyruvate fermentation to propanoate I: P108-PWY
  • 2 reactions found over 7 reactions in the full pathway
• PWY-5690, TCA cycle II (plants and fungi): PWY-5690
  • 8 reactions found over 9 reactions in the full pathway
• PWY66-398, TCA cycle III (animals): PWY66-398
  • 10 reactions found over 11 reactions in the full pathway
• PWY-6969, TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): PWY-6969
  • 10 reactions found over 12 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-aragem
    • Tool: pantograph
• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 12460
• PIR:
  • A47692
  • A49760
  • A64377
  • A81281
  • A81807
  • B44511
  • B81862
  • E64461
  • E64685
  • H70896
  • H71462
  • JC4293
  • JC4982
  • PA0062
  • S40448
  • S76348
  • T00433
  • T07374
  • T41265
  • T43727
  • T45269
  • UFBSC8
  • UFBYM
  • UFEC
  • UFECAQ
  • UFHUM
  • UFPG
  • UFRT
• LIGAND-RXN:
  • R01082
• UNIPROT:
  • Q04718
  • Q58034
  • O69294
  • Q9JTE3
  • P14407
  • Q9JTR0
  • Q58690
  • O25883
  • O53446
  • O84863
  • Q51404
  • Q7M4Z3
  • P39461
  • Q55674
  • P93033
  • Q43180
  • O94552
  • O66271
  • Q60022
  • P07343
  • P08417
  • P05042
  • P0AC33
  • P10173
  • P14408