PWY-5188

Reaction DIHYDROXYMETVALDEHYDRAT-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 2,3-Dihydroxy-3-methylvalerate dehydratase
  • Dihydroxy-acid/6-phosphogluconate dehydratase
• ec number:
  • EC-4.2.1.9
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 1-KETO-2-METHYLVALERATE[c] => 1 WATER[c] + 1 2-KETO-3-METHYL-VALERATE[c]
• With common name(s):
  • 1 (R)-2,3-dihydroxy-3-methylpentanoate[c] => 1 H2O[c] + 1 (S)-3-methyl-2-oxopentanoate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Ec-03_000220
  • Source: annotation-esiliculosus_genome
    • Assignment: EC-NUMBER
  • Source: orthology-aragem

Pathways

• PWY-5103, L-isoleucine biosynthesis III: PWY-5103
  • 4 reactions found over 7 reactions in the full pathway
• ILEUSYN-PWY, L-isoleucine biosynthesis I (from threonine): ILEUSYN-PWY
  • 7 reactions found over 7 reactions in the full pathway
• PWY-5101, L-isoleucine biosynthesis II: PWY-5101
  • 4 reactions found over 8 reactions in the full pathway
• PWY-5104, L-isoleucine biosynthesis IV: PWY-5104
  • 3 reactions found over 6 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-aragem
    • Tool: pantograph
• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 27694
• LIGAND-RXN:
  • R05070
• UNIPROT:
  • P55186
  • Q9JUE0
  • P05791
  • Q9UZ03
  • P44851
  • Q02139
  • Q9PJ98
  • P39522