Ec-08 005740

Reaction GLUTATHIONE-REDUCT-NADPH-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • Pyridine nucleotide-disulphide oxidoreductase, NAD-binding domain
  • FAD/NAD-linked reductase, dimerisation domain
• ec number:
  • EC-1.8.1.7
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 OXIDIZED-GLUTATHIONE[c] + 1 PROTON[c] + 1 NADPH[c] => 2 GLUTATHIONE[c] + 1 NADP[c]
• With common name(s):
  • 1 glutathione disulfide[c] + 1 H+[c] + 1 NADPH[c] => 2 glutathione[c] + 1 NADP+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Ec-24_001330
  • Source: annotation-esiliculosus_genome
    • Assignment: EC-NUMBER
  • Source: orthology-aragem
• Gene: Ec-00_010830
  • Source: annotation-esiliculosus_genome
    • Assignment: EC-NUMBER
  • Source: orthology-aragem

Pathways

• GLUT-REDOX-PWY, glutathione-glutaredoxin redox reactions: GLUT-REDOX-PWY
  • 2 reactions found over 2 reactions in the full pathway
• PWY-4081, glutathione-peroxide redox reactions: PWY-4081
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-aragem
    • Tool: pantograph
• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 11740
• LIGAND-RXN:
  • R00115
• UNIPROT:
  • P43783
  • Q9CH92
  • P48639
  • P11804
  • P06715
  • P23189
  • P80461
  • Q60151
  • P41921
  • Q9TWE1
  • O64409
  • Q43621
  • P48640
  • Q43154
  • Q93379
  • P78965
  • P42770