RXN-924

Reaction SUCCCOASYN-RXN

• direction:
  • REVERSIBLE
• common name:
  • Succinate:CoA ligase (ADP-forming)
• ec number:
  • EC-6.2.1.5
• Synonym(s):
  • Succinate thiokinase
  • succinyl CoA synthesis

Reaction Formula

• With identifiers:
  • 1 CO-A[c] + 1 SUC[c] + 1 ATP[c] <=> 1 ADP[c] + 1 Pi[c] + 1 SUC-COA[c]
• With common name(s):
  • 1 coenzyme A[c] + 1 succinate[c] + 1 ATP[c] <=> 1 ADP[c] + 1 phosphate[c] + 1 succinyl-CoA[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Ec-10_000030
  • pantograph-aragem
• Ec-02_001020
  • ESILICULOSUS_GENOME
    • EC-NUMBER
  • pantograph-aragem

Pathways

• PWY-5913, partial TCA cycle (obligate autotrophs): PWY-5913
  • 10 reactions found over 11 reactions in the full pathway
• P42-PWY, incomplete reductive TCA cycle: P42-PWY
  • 5 reactions found over 7 reactions in the full pathway
• PWY-7384, anaerobic energy metabolism (invertebrates, mitochondrial): PWY-7384
  • 6 reactions found over 12 reactions in the full pathway
• PWY-5392, reductive TCA cycle II: PWY-5392
  • 6 reactions found over 12 reactions in the full pathway
• TCA, TCA cycle I (prokaryotic): TCA
  • 9 reactions found over 10 reactions in the full pathway
• P23-PWY, reductive TCA cycle I: P23-PWY
  • 10 reactions found over 12 reactions in the full pathway
• PWY-6969, TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): PWY-6969
  • 10 reactions found over 12 reactions in the full pathway
• PWY-6728, methylaspartate cycle: PWY-6728
  • 11 reactions found over 18 reactions in the full pathway
• PWY-5538, pyruvate fermentation to acetate VI: PWY-5538
  • 2 reactions found over 4 reactions in the full pathway
• PWY-5690, TCA cycle II (plants and fungi): PWY-5690
  • 8 reactions found over 9 reactions in the full pathway
• PWY66-398, TCA cycle III (animals): PWY66-398
  • 10 reactions found over 11 reactions in the full pathway
• PWY-5537, pyruvate fermentation to acetate V: PWY-5537
  • 2 reactions found over 4 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-aragem
    • Tool: pantograph
• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 17661
• LIGAND-RXN:
  • R00405
• UNIPROT:
  • O28098
  • P53594
  • O28733
  • P45101
  • P45102
  • Q9JUT0
  • Q58643
  • O26663
  • P80886
  • Q9PHY1
  • Q9JUS9
  • P80865
  • Q9PHY0
  • O67729
  • O67546
  • P53593
  • P0AGE9
  • P0A836
  • O82662