RXN-12565

Reaction ACETYL-COA-ACETYLTRANSFER-RXN

• direction:
  • REVERSIBLE
• common name:
  • Thiolase, C-terminal
  • Acetyl-CoA acetyltransferase
• ec number:
  • EC-2.3.1.9
• Synonym(s):

Reaction Formula

• With identifiers:
  • 2 ACETYL-COA[c] <=> 1 CO-A[c] + 1 ACETOACETYL-COA[c]
• With common name(s):
  • 2 acetyl-CoA[c] <=> 1 coenzyme A[c] + 1 acetoacetyl-CoA[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Ec-26_003940
  • pantograph-aragem
• Ec-24_000870
  • ESILICULOSUS_GENOME
    • EC-NUMBER
• Ec-22_002850
  • ESILICULOSUS_GENOME
    • EC-NUMBER
  • pantograph-aragem
  • pantograph-aragem
  • pantograph-aragem
  • pantograph-aragem

Pathways

• P162-PWY, L-glutamate degradation V (via hydroxyglutarate): P162-PWY
  • 4 reactions found over 11 reactions in the full pathway
• PWY-5177, glutaryl-CoA degradation: PWY-5177
  • 3 reactions found over 5 reactions in the full pathway
• PWY-6583, pyruvate fermentation to butanol I: PWY-6583
  • 4 reactions found over 8 reactions in the full pathway
• P163-PWY, L-lysine fermentation to acetate and butanoate: P163-PWY
  • 1 reactions found over 10 reactions in the full pathway
• PWY-6883, pyruvate fermentation to butanol II (engineered): PWY-6883
  • 3 reactions found over 6 reactions in the full pathway
• PWY-5676, acetyl-CoA fermentation to butanoate II: PWY-5676
  • 1 reactions found over 7 reactions in the full pathway
• PWY-7778, 2-methylpropene degradation: PWY-7778
  • 2 reactions found over 8 reactions in the full pathway
• PWY-7779, methyl tert-butyl ether degradation: PWY-7779
  • 2 reactions found over 10 reactions in the full pathway
• PWY-6588, pyruvate fermentation to acetone: PWY-6588
  • 2 reactions found over 5 reactions in the full pathway
• PWY1-3, polyhydroxybutanoate biosynthesis: PWY1-3
  • 1 reactions found over 3 reactions in the full pathway
• PWY-5789, 3-hydroxypropanoate/4-hydroxybutanate cycle: PWY-5789
  • 6 reactions found over 16 reactions in the full pathway
• PWY-6876, isopropanol biosynthesis (engineered): PWY-6876
  • 2 reactions found over 5 reactions in the full pathway
• CENTFERM-PWY, pyruvate fermentation to butanoate: CENTFERM-PWY
  • 4 reactions found over 7 reactions in the full pathway
• PWY-7391, isoprene biosynthesis II (engineered): PWY-7391
  • 7 reactions found over 8 reactions in the full pathway
• PWY-5741, ethylmalonyl-CoA pathway: PWY-5741
  • 1 reactions found over 11 reactions in the full pathway
• PWY-6174, mevalonate pathway II (archaea): PWY-6174
  • 5 reactions found over 7 reactions in the full pathway
• ACETOACETATE-DEG-PWY, acetoacetate degradation (to acetyl CoA): ACETOACETATE-DEG-PWY
  • 1 reactions found over 2 reactions in the full pathway
• PWY66-367, ketogenesis: PWY66-367
  • 3 reactions found over 5 reactions in the full pathway
• PWY-7216, (R)- and (S)-3-hydroxybutanoate biosynthesis (engineered): PWY-7216
  • 2 reactions found over 5 reactions in the full pathway
• PWY-922, mevalonate pathway I: PWY-922
  • 7 reactions found over 7 reactions in the full pathway
• PWY66-368, ketolysis: PWY66-368
  • 1 reactions found over 3 reactions in the full pathway
• PWY-7401, crotonate fermentation (to acetate and cyclohexane carboxylate): PWY-7401
  • 4 reactions found over 16 reactions in the full pathway
• PWY-6863, pyruvate fermentation to hexanol (engineered): PWY-6863
  • 7 reactions found over 11 reactions in the full pathway
• PWY-7524, mevalonate pathway III (archaea): PWY-7524
  • 4 reactions found over 8 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-aragem
    • Tool: pantograph
• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 21036
• LIGAND-RXN:
  • R00238
• UNIPROT:
  • Q8CAY6
  • P41338
  • P45362
  • Q9BWD1
  • P45359
  • P24752
  • Q12598
  • P45369
  • P46707
  • P73825
  • Q43637
  • Q9UQW6
  • Q9Z3Y4
  • P77852
  • Q9XD81
  • Q9ZGI9
  • Q9L8E0
  • P14611
  • P07097
  • P17764