IMP-DEHYDROG-RXN

Reaction IMP-DEHYDROG-RXN

• direction:
  • REVERSIBLE
• common name:
  • IMP dehydrogenase/GMP reductase
  • IMP dehydrogenase
• ec number:
  • EC-1.1.1.205
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 NAD[c] + 1 IMP[c] + 1 WATER[c] <=> 1 XANTHOSINE-5-PHOSPHATE[c] + 1 NADH[c] + 1 PROTON[c]
• With common name(s):
  • 1 NAD+[c] + 1 IMP[c] + 1 H2O[c] <=> 1 XMP[c] + 1 NADH[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Ec-24_002410
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
  • Source: orthology-aragem
• Gene: Ec-19_000030
  • Source: annotation-esiliculosus_genome
    • Assignment: AUTOMATED-NAME-MATCH
  • Source: orthology-aragem

Pathways

• PWY-7221, guanosine ribonucleotides de novo biosynthesis: PWY-7221
  • 4 reactions found over 4 reactions in the full pathway
• PWY-5695, urate biosynthesis/inosine 5'-phosphate degradation: PWY-5695
  • 3 reactions found over 4 reactions in the full pathway
• PWY-6596, adenosine nucleotides degradation I: PWY-6596
  • 6 reactions found over 8 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-aragem
    • Tool: pantograph
• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 11708
• LIGAND-RXN:
  • R01130
• UNIPROT:
  • P12268
  • P21620
  • P50098
  • P50097
  • O26245
  • Q9PAR5
  • P65172
  • Q9X168
  • Q9KTW3
  • Q9YBU2
  • Q9CIY6
  • P21879
  • P0ADG7
  • P56088
  • P49058
  • O58045
  • Q9UY49
  • Q9PKM2
  • Q9RT87
  • Q9JUD0
  • Q59011
  • Q9PNN3
  • P44334
  • O67820
  • P65167
  • Q9ZL14
  • Q9JZB5
  • Q9HXM5
  • P0C0H6
  • P42851
  • P47996
  • Q9RHG9
  • P24547
  • Q9RHG1
  • P31002
  • Q07152
  • P38697
  • P50094
  • P39567
  • P50095
  • Q49729
  • O14344
  • O32912