Ec-11 000450

Reaction LEUKOTRIENE-A4-HYDROLASE-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
  • Leukotriene-A(4) hydrolase
• ec number:
  • EC-3.3.2.6
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CPD-8892[c] + 1 WATER[c] => 1 6Z8E10E14Z-5S12R-512-DIHYDROXYI[c]
• With common name(s):
  • 1 leukotriene A4[c] + 1 H2O[c] => 1 leukotriene B4[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Ec-05_005680
  • ESILICULOSUS_GENOME
    • EC-NUMBER
  • pantograph-aragem
• Ec-27_001510
  • ESILICULOSUS_GENOME
    • AUTOMATED-NAME-MATCH

Pathways

• PWY66-375, leukotriene biosynthesis: PWY66-375
  • 2 reactions found over 6 reactions in the full pathway

Reconstruction information

• orthology:
  • pantograph:
    • aragem
• annotation:
  • pathwaytools:
    • esiliculosus_genome

External links

• RHEA:
  • 22324
• LIGAND-RXN:
  • R03057
• UNIPROT:
  • P19602
  • P24527
  • P30349
  • P09960
  • O44969