Difference between revisions of "2.7.1.127-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=DIHYDROFOLATE DIHYDROFOLATE] == * smiles: ** C(NC1(C=CC(C(=O)NC(C(=O)[O-])CCC([O-])=O)=CC=1))C3...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=2.7.1.127-RXN 2.7.1.127-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** inositol-1,4,5-tris...")
 
(2 intermediate revisions by the same user not shown)
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=DIHYDROFOLATE DIHYDROFOLATE] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=2.7.1.127-RXN 2.7.1.127-RXN] ==
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* smiles:
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* direction:
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** C(NC1(C=CC(C(=O)NC(C(=O)[O-])CCC([O-])=O)=CC=1))C3(CNC2(=C(C(=O)NC(N)=N2)N=3))
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** LEFT-TO-RIGHT
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* inchi key:
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** InChIKey=OZRNSSUDZOLUSN-LBPRGKRZSA-L
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* common name:
 
* common name:
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** 7,8-dihydrofolate monoglutamate
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** inositol-1,4,5-trisphosphate 3-kinase
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* molecular weight:
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* ec number:
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** 441.402   
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** [http://enzyme.expasy.org/EC/2.7.1.127 EC-2.7.1.127]
 
* Synonym(s):
 
* Synonym(s):
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** 7,8-pteroylglutamic acid
 
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** 7,8-pteroylglutamate
 
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** 7,8-dihydropteroyl monoglutamate
 
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** H2PteGlu
 
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** H2PteGlu1
 
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** dihydrofolate
 
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** 7,8-dihydropteroylglutamate
 
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** 7,8-dihydrofolate
 
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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* [[DIHYDROFOLATEREDUCT-RXN-THF/NADP//DIHYDROFOLATE/NADPH/PROTON.37.]]
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* With identifiers:
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== Reaction(s) known to produce the compound ==
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** 1 [[INOSITOL-1-4-5-TRISPHOSPHATE]][c] '''+''' 1 [[ATP]][c] '''=>''' 1 [[PROTON]][c] '''+''' 1 [[ADP]][c] '''+''' 1 [[CPD-506]][c]
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* [[DIHYDROFOLATESYNTH-RXN]]
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* With common name(s):
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== Reaction(s) of unknown directionality ==
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** 1 D-myo-inositol (1,4,5)-trisphosphate[c] '''+''' 1 ATP[c] '''=>''' 1 H+[c] '''+''' 1 ADP[c] '''+''' 1 D-myo-inositol (1,3,4,5)-tetrakisphosphate[c]
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[Ec-16_003350]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Assignment: GO-TERM
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== Pathways  ==
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* [[PWY-6364]], D-myo-inositol (1,3,4)-trisphosphate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6364 PWY-6364]
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** '''1''' reactions found over '''3''' reactions in the full pathway
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* [[PWY-6362]], 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6362 PWY-6362]
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** '''4''' reactions found over '''5''' reactions in the full pathway
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* [[PWY-6361]], 1D-myo-inositol hexakisphosphate biosynthesis I  (from Ins(1,4,5)P3): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6361 PWY-6361]
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** '''2''' reactions found over '''5''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[annotation]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* CAS : 4033-27-6
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* RHEA:
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* BIGG : 34911
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=11020 11020]
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* PUBCHEM:
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* LIGAND-RXN:
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=40480038 40480038]
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** [http://www.genome.jp/dbget-bin/www_bget?R03433 R03433]
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* HMDB : HMDB01056
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* UNIPROT:
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* LIGAND-CPD:
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** [http://www.uniprot.org/uniprot/P23677 P23677]
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** [http://www.genome.jp/dbget-bin/www_bget?C00415 C00415]
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** [http://www.uniprot.org/uniprot/P17105 P17105]
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* CHEBI:
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** [http://www.uniprot.org/uniprot/P42335 P42335]
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57451 57451]
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** [http://www.uniprot.org/uniprot/O45049 O45049]
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* METABOLIGHTS : MTBLC57451
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** [http://www.uniprot.org/uniprot/O45050 O45050]
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{{#set: smiles=C(NC1(C=CC(C(=O)NC(C(=O)[O-])CCC([O-])=O)=CC=1))C3(CNC2(=C(C(=O)NC(N)=N2)N=3))}}
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** [http://www.uniprot.org/uniprot/O45051 O45051]
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{{#set: inchi key=InChIKey=OZRNSSUDZOLUSN-LBPRGKRZSA-L}}
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{{#set: direction=LEFT-TO-RIGHT}}
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{{#set: common name=7,8-dihydrofolate monoglutamate}}
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{{#set: common name=inositol-1,4,5-trisphosphate 3-kinase}}
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{{#set: molecular weight=441.402    }}
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{{#set: ec number=EC-2.7.1.127}}
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{{#set: common name=7,8-pteroylglutamic acid|7,8-pteroylglutamate|7,8-dihydropteroyl monoglutamate|H2PteGlu|H2PteGlu1|dihydrofolate|7,8-dihydropteroylglutamate|7,8-dihydrofolate}}
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{{#set: gene associated=Ec-16_003350}}
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{{#set: consumed by=DIHYDROFOLATEREDUCT-RXN-THF/NADP//DIHYDROFOLATE/NADPH/PROTON.37.}}
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{{#set: in pathway=PWY-6364|PWY-6362|PWY-6361}}
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{{#set: produced by=DIHYDROFOLATESYNTH-RXN}}
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{{#set: reconstruction category=annotation}}
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{{#set: reconstruction source=annotation-esiliculosus_genome}}
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{{#set: reconstruction tool=pathwaytools}}

Latest revision as of 20:34, 21 March 2018

Reaction 2.7.1.127-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • inositol-1,4,5-trisphosphate 3-kinase
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 D-myo-inositol (1,4,5)-trisphosphate[c] + 1 ATP[c] => 1 H+[c] + 1 ADP[c] + 1 D-myo-inositol (1,3,4,5)-tetrakisphosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6364, D-myo-inositol (1,3,4)-trisphosphate biosynthesis: PWY-6364
    • 1 reactions found over 3 reactions in the full pathway
  • PWY-6362, 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian): PWY-6362
    • 4 reactions found over 5 reactions in the full pathway
  • PWY-6361, 1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3): PWY-6361
    • 2 reactions found over 5 reactions in the full pathway

Reconstruction information

External links





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