Difference between revisions of "FUMHYDR-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-5467 RXN-5467] == * direction: ** LEFT-TO-RIGHT * common name: ** Dolichyl-P-Man:Man(5)GlcNAc(2...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=FUMHYDR-RXN FUMHYDR-RXN] == * direction: ** REVERSIBLE * common name: ** Fumarate lyase, N-terminal...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-5467 RXN-5467] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=FUMHYDR-RXN FUMHYDR-RXN] ==
 
* direction:
 
* direction:
** LEFT-TO-RIGHT
+
** REVERSIBLE
 
* common name:
 
* common name:
** Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase, family GT58
+
** Fumarate lyase, N-terminal
 +
** fumarate hydratase
 
* ec number:
 
* ec number:
** [http://enzyme.expasy.org/EC/2.4.1.259 EC-2.4.1.259]
+
** [http://enzyme.expasy.org/EC/4.2.1.2 EC-4.2.1.2]
 
* Synonym(s):
 
* Synonym(s):
 +
** fumarate hydration
 +
** malate dehydration
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
** 1 [[CPD-171]][c] '''+''' 1 [[CPD-5165]][c] '''=>''' 1 [[CPD-5166]][c] '''+''' 1 [[DOLICHOLP]][c] '''+''' 1 [[PROTON]][c]
+
** 1 [[MAL]][c] '''<=>''' 1 [[FUM]][c] '''+''' 1 [[WATER]][c]
 
* With common name(s):
 
* With common name(s):
** 1 a dolichyl &beta;-D-mannosyl phosphate[c] '''+''' 1 a (mannosyl)6-(N-acetylglucosaminyl)2-diphosphodolichol[c] '''=>''' 1 a (mannosyl)7-(N-acetylglucosaminyl)2-diphosphodolichol[c] '''+''' 1 a dolichyl phosphate[c] '''+''' 1 H+[c]
+
** 1 (S)-malate[c] '''<=>''' 1 fumarate[c] '''+''' 1 H2O[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
* [[Ec-12_007710]]
+
* Gene: [[Ec-25_001360]]
** ESILICULOSUS_GENOME
+
** Source: [[annotation-esiliculosus_genome]]
***EC-NUMBER
+
*** Assignment: GO-TERM
 +
* Gene: [[Ec-23_003460]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[orthology-aragem]]
 
== Pathways  ==
 
== Pathways  ==
* [[MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS]], protein N-glycosylation (eukaryotic, high mannose): [http://metacyc.org/META/NEW-IMAGE?object=MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS]
+
* [[PWY-561]], superpathway of glyoxylate cycle and fatty acid degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-561 PWY-561]
** '''19''' reactions found over '''19''' reactions in the full pathway
+
** '''6''' reactions found over '''8''' reactions in the full pathway
 +
* [[PWY-5913]], partial TCA cycle (obligate autotrophs): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5913 PWY-5913]
 +
** '''10''' reactions found over '''11''' reactions in the full pathway
 +
* [[P42-PWY]], incomplete reductive TCA cycle: [http://metacyc.org/META/NEW-IMAGE?object=P42-PWY P42-PWY]
 +
** '''5''' reactions found over '''7''' reactions in the full pathway
 +
* [[PWY-7384]], anaerobic energy metabolism (invertebrates, mitochondrial): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7384 PWY-7384]
 +
** '''6''' reactions found over '''12''' reactions in the full pathway
 +
* [[PWY-5392]], reductive TCA cycle II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5392 PWY-5392]
 +
** '''6''' reactions found over '''12''' reactions in the full pathway
 +
* [[TCA]], TCA cycle I (prokaryotic): [http://metacyc.org/META/NEW-IMAGE?object=TCA TCA]
 +
** '''9''' reactions found over '''10''' reactions in the full pathway
 +
* [[P23-PWY]], reductive TCA cycle I: [http://metacyc.org/META/NEW-IMAGE?object=P23-PWY P23-PWY]
 +
** '''10''' reactions found over '''12''' reactions in the full pathway
 +
* [[P105-PWY]], TCA cycle IV (2-oxoglutarate decarboxylase): [http://metacyc.org/META/NEW-IMAGE?object=P105-PWY P105-PWY]
 +
** '''9''' reactions found over '''11''' reactions in the full pathway
 +
* [[FERMENTATION-PWY]], mixed acid fermentation: [http://metacyc.org/META/NEW-IMAGE?object=FERMENTATION-PWY FERMENTATION-PWY]
 +
** '''8''' reactions found over '''16''' reactions in the full pathway
 +
* [[PWY-6728]], methylaspartate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6728 PWY-6728]
 +
** '''11''' reactions found over '''18''' reactions in the full pathway
 +
* [[REDCITCYC]], TCA cycle VIII (helicobacter): [http://metacyc.org/META/NEW-IMAGE?object=REDCITCYC REDCITCYC]
 +
** '''5''' reactions found over '''9''' reactions in the full pathway
 +
* [[PWY-7254]], TCA cycle VII (acetate-producers): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7254 PWY-7254]
 +
** '''7''' reactions found over '''9''' reactions in the full pathway
 +
* [[P108-PWY]], pyruvate fermentation to propanoate I: [http://metacyc.org/META/NEW-IMAGE?object=P108-PWY P108-PWY]
 +
** '''2''' reactions found over '''7''' reactions in the full pathway
 +
* [[PWY-5690]], TCA cycle II (plants and fungi): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5690 PWY-5690]
 +
** '''8''' reactions found over '''9''' reactions in the full pathway
 +
* [[PWY66-398]], TCA cycle III (animals): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-398 PWY66-398]
 +
** '''10''' reactions found over '''11''' reactions in the full pathway
 +
* [[PWY-6969]], TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6969 PWY-6969]
 +
** '''10''' reactions found over '''12''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
* [[annotation]]:
+
* Category: [[orthology]]
** [[pathwaytools]]:
+
** Source: [[orthology-aragem]]
*** [[esiliculosus_genome]]
+
*** Tool: [[pantograph]]
 +
* Category: [[annotation]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=29534 29534]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=12460 12460]
 +
* PIR:
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A47692 A47692]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A49760 A49760]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A64377 A64377]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A81281 A81281]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A81807 A81807]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=B44511 B44511]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=B81862 B81862]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=E64461 E64461]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=E64685 E64685]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=H70896 H70896]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=H71462 H71462]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=JC4293 JC4293]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=JC4982 JC4982]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=PA0062 PA0062]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S40448 S40448]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S76348 S76348]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T00433 T00433]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T07374 T07374]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T41265 T41265]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T43727 T43727]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T45269 T45269]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFBSC8 UFBSC8]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFBYM UFBYM]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFEC UFEC]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFECAQ UFECAQ]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFHUM UFHUM]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFPG UFPG]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFRT UFRT]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
** [http://www.genome.jp/dbget-bin/www_bget?R06259 R06259]
+
** [http://www.genome.jp/dbget-bin/www_bget?R01082 R01082]
{{#set: direction=LEFT-TO-RIGHT}}
+
* UNIPROT:
{{#set: common name=Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase, family GT58}}
+
** [http://www.uniprot.org/uniprot/Q04718 Q04718]
{{#set: ec number=EC-2.4.1.259}}
+
** [http://www.uniprot.org/uniprot/Q58034 Q58034]
{{#set: gene associated=Ec-12_007710}}
+
** [http://www.uniprot.org/uniprot/O69294 O69294]
{{#set: in pathway=MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS}}
+
** [http://www.uniprot.org/uniprot/Q9JTE3 Q9JTE3]
{{#set: reconstruction category=annotation}}
+
** [http://www.uniprot.org/uniprot/P14407 P14407]
{{#set: reconstruction tool=pathwaytools}}
+
** [http://www.uniprot.org/uniprot/Q9JTR0 Q9JTR0]
{{#set: reconstruction source=esiliculosus_genome}}
+
** [http://www.uniprot.org/uniprot/Q58690 Q58690]
 +
** [http://www.uniprot.org/uniprot/O25883 O25883]
 +
** [http://www.uniprot.org/uniprot/O53446 O53446]
 +
** [http://www.uniprot.org/uniprot/O84863 O84863]
 +
** [http://www.uniprot.org/uniprot/Q51404 Q51404]
 +
** [http://www.uniprot.org/uniprot/Q7M4Z3 Q7M4Z3]
 +
** [http://www.uniprot.org/uniprot/P39461 P39461]
 +
** [http://www.uniprot.org/uniprot/Q55674 Q55674]
 +
** [http://www.uniprot.org/uniprot/P93033 P93033]
 +
** [http://www.uniprot.org/uniprot/Q43180 Q43180]
 +
** [http://www.uniprot.org/uniprot/O94552 O94552]
 +
** [http://www.uniprot.org/uniprot/O66271 O66271]
 +
** [http://www.uniprot.org/uniprot/Q60022 Q60022]
 +
** [http://www.uniprot.org/uniprot/P07343 P07343]
 +
** [http://www.uniprot.org/uniprot/P08417 P08417]
 +
** [http://www.uniprot.org/uniprot/P05042 P05042]
 +
** [http://www.uniprot.org/uniprot/P0AC33 P0AC33]
 +
** [http://www.uniprot.org/uniprot/P10173 P10173]
 +
** [http://www.uniprot.org/uniprot/P14408 P14408]
 +
{{#set: direction=REVERSIBLE}}
 +
{{#set: common name=Fumarate lyase, N-terminal}}
 +
{{#set: common name=fumarate hydratase}}
 +
{{#set: ec number=EC-4.2.1.2}}
 +
{{#set: common name=fumarate hydration|malate dehydration}}
 +
{{#set: gene associated=Ec-25_001360|Ec-23_003460}}
 +
{{#set: in pathway=PWY-561|PWY-5913|P42-PWY|PWY-7384|PWY-5392|TCA|P23-PWY|P105-PWY|FERMENTATION-PWY|PWY-6728|REDCITCYC|PWY-7254|P108-PWY|PWY-5690|PWY66-398|PWY-6969}}
 +
{{#set: reconstruction category=orthology|annotation}}
 +
{{#set: reconstruction source=annotation-esiliculosus_genome|orthology-aragem}}
 +
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 20:24, 21 March 2018

Reaction FUMHYDR-RXN

  • direction:
    • REVERSIBLE
  • common name:
    • Fumarate lyase, N-terminal
    • fumarate hydratase
  • ec number:
  • Synonym(s):
    • fumarate hydration
    • malate dehydration

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 (S)-malate[c] <=> 1 fumarate[c] + 1 H2O[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-561, superpathway of glyoxylate cycle and fatty acid degradation: PWY-561
    • 6 reactions found over 8 reactions in the full pathway
  • PWY-5913, partial TCA cycle (obligate autotrophs): PWY-5913
    • 10 reactions found over 11 reactions in the full pathway
  • P42-PWY, incomplete reductive TCA cycle: P42-PWY
    • 5 reactions found over 7 reactions in the full pathway
  • PWY-7384, anaerobic energy metabolism (invertebrates, mitochondrial): PWY-7384
    • 6 reactions found over 12 reactions in the full pathway
  • PWY-5392, reductive TCA cycle II: PWY-5392
    • 6 reactions found over 12 reactions in the full pathway
  • TCA, TCA cycle I (prokaryotic): TCA
    • 9 reactions found over 10 reactions in the full pathway
  • P23-PWY, reductive TCA cycle I: P23-PWY
    • 10 reactions found over 12 reactions in the full pathway
  • P105-PWY, TCA cycle IV (2-oxoglutarate decarboxylase): P105-PWY
    • 9 reactions found over 11 reactions in the full pathway
  • FERMENTATION-PWY, mixed acid fermentation: FERMENTATION-PWY
    • 8 reactions found over 16 reactions in the full pathway
  • PWY-6728, methylaspartate cycle: PWY-6728
    • 11 reactions found over 18 reactions in the full pathway
  • REDCITCYC, TCA cycle VIII (helicobacter): REDCITCYC
    • 5 reactions found over 9 reactions in the full pathway
  • PWY-7254, TCA cycle VII (acetate-producers): PWY-7254
    • 7 reactions found over 9 reactions in the full pathway
  • P108-PWY, pyruvate fermentation to propanoate I: P108-PWY
    • 2 reactions found over 7 reactions in the full pathway
  • PWY-5690, TCA cycle II (plants and fungi): PWY-5690
    • 8 reactions found over 9 reactions in the full pathway
  • PWY66-398, TCA cycle III (animals): PWY66-398
    • 10 reactions found over 11 reactions in the full pathway
  • PWY-6969, TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): PWY-6969
    • 10 reactions found over 12 reactions in the full pathway

Reconstruction information

External links