Difference between revisions of "LEUKOTRIENE-A4-HYDROLASE-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=PROPIONYL-COA-CARBOXY-RXN PROPIONYL-COA-CARBOXY-RXN] == * direction: ** REVERSIBLE * common name: *...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=LEUKOTRIENE-A4-HYDROLASE-RXN LEUKOTRIENE-A4-HYDROLASE-RXN] == * direction: ** LEFT-TO-RIGHT * commo...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=PROPIONYL-COA-CARBOXY-RXN PROPIONYL-COA-CARBOXY-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=LEUKOTRIENE-A4-HYDROLASE-RXN LEUKOTRIENE-A4-HYDROLASE-RXN] ==
 
* direction:
 
* direction:
−
** REVERSIBLE
+
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
−
** propionyl-CoA carboxylase, alpha subunit
+
** Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
 +
** Leukotriene-A(4) hydrolase
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/6.4.1.3 EC-6.4.1.3]
+
** [http://enzyme.expasy.org/EC/3.3.2.6 EC-3.3.2.6]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[HCO3]][c] '''+''' 1 [[ATP]][c] '''+''' 1 [[PROPIONYL-COA]][c] '''<=>''' 1 [[D-METHYL-MALONYL-COA]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[ADP]][c] '''+''' 1 [[Pi]][c]
+
** 1 [[CPD-8892]][c] '''+''' 1 [[WATER]][c] '''=>''' 1 [[6Z8E10E14Z-5S12R-512-DIHYDROXYI]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 hydrogen carbonate[c] '''+''' 1 ATP[c] '''+''' 1 propanoyl-CoA[c] '''<=>''' 1 (S)-methylmalonyl-CoA[c] '''+''' 1 H+[c] '''+''' 1 ADP[c] '''+''' 1 phosphate[c]
+
** 1 leukotriene A4[c] '''+''' 1 H2O[c] '''=>''' 1 leukotriene B4[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* Gene: [[Ec-01_010970]]
+
* Gene: [[Ec-27_001510]]
 +
** Source: [[annotation-esiliculosus_genome]]
 +
*** Assignment: AUTOMATED-NAME-MATCH
 +
* Gene: [[Ec-05_005680]]
 
** Source: [[annotation-esiliculosus_genome]]
 
** Source: [[annotation-esiliculosus_genome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
 +
** Source: [[orthology-aragem]]
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-5743]], 3-hydroxypropanoate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5743 PWY-5743]
+
* [[PWY66-375]], leukotriene biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY66-375 PWY66-375]
−
** '''3''' reactions found over '''11''' reactions in the full pathway
+
** '''2''' reactions found over '''6''' reactions in the full pathway
−
* [[PWY-7384]], anaerobic energy metabolism (invertebrates, mitochondrial): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7384 PWY-7384]
+
−
** '''6''' reactions found over '''12''' reactions in the full pathway
+
−
* [[PWY-5789]], 3-hydroxypropanoate/4-hydroxybutanate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5789 PWY-5789]
+
−
** '''6''' reactions found over '''16''' reactions in the full pathway
+
−
* [[PROPIONMET-PWY]], propanoyl CoA degradation I: [http://metacyc.org/META/NEW-IMAGE?object=PROPIONMET-PWY PROPIONMET-PWY]
+
−
** '''1''' reactions found over '''3''' reactions in the full pathway
+
−
* [[PWY-6728]], methylaspartate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6728 PWY-6728]
+
−
** '''11''' reactions found over '''18''' reactions in the full pathway
+
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 +
* Category: [[orthology]]
 +
** Source: [[orthology-aragem]]
 +
*** Tool: [[pantograph]]
 
* Category: [[annotation]]
 
* Category: [[annotation]]
 
** Source: [[annotation-esiliculosus_genome]]
 
** Source: [[annotation-esiliculosus_genome]]
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== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=23720 23720]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=22324 22324]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R01859 R01859]
+
** [http://www.genome.jp/dbget-bin/www_bget?R03057 R03057]
 
* UNIPROT:
 
* UNIPROT:
−
** [http://www.uniprot.org/uniprot/Q96CX0 Q96CX0]
+
** [http://www.uniprot.org/uniprot/P19602 P19602]
−
** [http://www.uniprot.org/uniprot/P07633 P07633]
+
** [http://www.uniprot.org/uniprot/P24527 P24527]
−
** [http://www.uniprot.org/uniprot/P05165 P05165]
+
** [http://www.uniprot.org/uniprot/P30349 P30349]
−
** [http://www.uniprot.org/uniprot/Q06101 Q06101]
+
** [http://www.uniprot.org/uniprot/P09960 P09960]
−
** [http://www.uniprot.org/uniprot/Q20676 Q20676]
+
** [http://www.uniprot.org/uniprot/O44969 O44969]
−
** [http://www.uniprot.org/uniprot/O24789 O24789]
+
{{#set: direction=LEFT-TO-RIGHT}}
−
{{#set: direction=REVERSIBLE}}
+
{{#set: common name=Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase}}
−
{{#set: common name=propionyl-CoA carboxylase, alpha subunit}}
+
{{#set: common name=Leukotriene-A(4) hydrolase}}
−
{{#set: ec number=EC-6.4.1.3}}
+
{{#set: ec number=EC-3.3.2.6}}
−
{{#set: gene associated=Ec-01_010970}}
+
{{#set: gene associated=Ec-27_001510|Ec-05_005680}}
−
{{#set: in pathway=PWY-5743|PWY-7384|PWY-5789|PROPIONMET-PWY|PWY-6728}}
+
{{#set: in pathway=PWY66-375}}
−
{{#set: reconstruction category=annotation}}
+
{{#set: reconstruction category=orthology|annotation}}
−
{{#set: reconstruction source=annotation-esiliculosus_genome}}
+
{{#set: reconstruction source=annotation-esiliculosus_genome|orthology-aragem}}
−
{{#set: reconstruction tool=pathwaytools}}
+
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 20:40, 21 March 2018

Reaction LEUKOTRIENE-A4-HYDROLASE-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
    • Leukotriene-A(4) hydrolase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY66-375, leukotriene biosynthesis: PWY66-375
    • 2 reactions found over 6 reactions in the full pathway

Reconstruction information

External links





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