PDH

Reaction PDH

• direction:
  • LEFT-TO-RIGHT
• common name:
  • Pyruvate dehydrogenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1.0 nad[c] + 1.0 coa[c] + 1.0 pyr[c] => 1.0 co2[c] + 1.0 nadh[c] + 1.0 accoa[c]
• With common name(s):
  • 1.0 Nicotinamide adenine dinucleotide[c] + 1.0 Coenzyme A[c] + 1.0 Pyruvate[c] => 1.0 CO2 CO2[c] + 1.0 Nicotinamide adenine dinucleotide - reduced[c] + 1.0 Acetyl-CoA[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: EF1353
  • Source: orthology-l_plantarum_wcfs1
  • Source: orthology-b_subtilis_subsp_subtilis_str168
• Gene: EF1356
  • Source: orthology-l_plantarum_wcfs1
  • Source: orthology-b_subtilis_subsp_subtilis_str168
• Gene: EF1355
  • Source: orthology-l_plantarum_wcfs1
  • Source: orthology-b_subtilis_subsp_subtilis_str168
• Gene: EF1354
  • Source: orthology-l_plantarum_wcfs1
  • Source: orthology-b_subtilis_subsp_subtilis_str168

Pathways

• map01100: map01100
  • 460 reactions found over 2349 reactions in the full pathway
• map01110: map01110
  • 179 reactions found over 1054 reactions in the full pathway
• map01120: map01120
  • 104 reactions found over 715 reactions in the full pathway
• map01200: map01200
  • 45 reactions found over 220 reactions in the full pathway
• map00620: map00620
  • 31 reactions found over 163 reactions in the full pathway
• map00010: map00010
  • 24 reactions found over 149 reactions in the full pathway
• map00020: map00020
  • 4 reactions found over 70 reactions in the full pathway
• map01130: map01130
  • 135 reactions found over 694 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-b_subtilis_subsp_subtilis_str168
    • Tool: pantograph
  • Source: orthology-l_plantarum_wcfs1
    • Tool: pantograph

External links

• EC Number : 1.2.1
• BioCyc : META:PYRUVDEH-RXN
• MetaNetX (MNX) Equation : MNXR102425
• RHEA:
  • 28042
• Reactome : REACT_R-ATH-71397
• KEGG Reaction : R00209