PRFGS

Reaction PRFGS

• direction:
  • LEFT-TO-RIGHT
• common name:
  • Phosphoribosylformylglycinamidine synthase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1.0 atp[c] + 1.0 fgam[c] + 1.0 h2o[c] + 1.0 gln__L[c] => 1.0 fpram[c] + 1.0 pi[c] + 1.0 h[c] + 1.0 glu__L[c] + 1.0 adp[c]
• With common name(s):
  • 1.0 ATP C10H12N5O13P3[c] + 1.0 N2-Formyl-N1-(5-phospho-D-ribosyl)glycinamide[c] + 1.0 H2O H2O[c] + 1.0 L-Glutamine[c] => 1.0 2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine[c] + 1.0 Phosphate[c] + 1.0 H+[c] + 1.0 L-Glutamate[c] + 1.0 ADP C10H12N5O10P2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: EF1784
  • Source: orthology-l_plantarum_wcfs1
• Gene: EF1782
  • Source: orthology-l_plantarum_wcfs1
  • Source: orthology-e_coli_sstr_k12_substr_mg1655
• Gene: EF1783
  • Source: orthology-l_plantarum_wcfs1

Pathways

• map01100: map01100
  • 460 reactions found over 2349 reactions in the full pathway
• map01130: map01130
  • 135 reactions found over 694 reactions in the full pathway
• map01110: map01110
  • 179 reactions found over 1054 reactions in the full pathway
• map00230: map00230
  • 97 reactions found over 298 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-e_coli_sstr_k12_substr_mg1655
    • Tool: pantograph
  • Source: orthology-l_plantarum_wcfs1
    • Tool: pantograph

External links

• RHEA:
  • 17129
• MetaNetX (MNX) Equation : MNXR103165
• EC Number : 6.3.5.3