Difference between revisions of "DHFR"

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(Created page with "Category:Reaction == Reaction [http://bigg.ucsd.edu/universal/reactions/SDPDS SDPDS] == * direction: ** LEFT-TO-RIGHT * common name: ** Succinyl-diaminopimelate desuccinyl...")
(Created page with "Category:Reaction == Reaction [http://bigg.ucsd.edu/universal/reactions/DHFR DHFR] == * direction: ** REVERSIBLE * common name: ** Dihydrofolate reductase * Synonym(s): =...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://bigg.ucsd.edu/universal/reactions/SDPDS SDPDS] ==
+
== Reaction [http://bigg.ucsd.edu/universal/reactions/DHFR DHFR] ==
 
* direction:
 
* direction:
−
** LEFT-TO-RIGHT
+
** REVERSIBLE
 
* common name:
 
* common name:
−
** Succinyl-diaminopimelate desuccinylase
+
** Dihydrofolate reductase
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1.0 [[h2o]][c] '''+''' 1.0 [[sl26da]][c] '''=>''' 1.0 [[26dap_LL]][c] '''+''' 1.0 [[succ]][c]
+
** 1.0 [[h]][c] '''+''' 1.0 [[dhf]][c] '''+''' 1.0 [[nadph]][c] '''<=>''' 1.0 [[thf]][c] '''+''' 1.0 [[nadp]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1.0 H2O H2O[c] '''+''' 1.0 N-Succinyl-LL-2,6-diaminoheptanedioate[c] '''=>''' 1.0 LL-2,6-Diaminoheptanedioate[c] '''+''' 1.0 Succinate[c]
+
** 1.0 H+[c] '''+''' 1.0 7,8-Dihydrofolate[c] '''+''' 1.0 Nicotinamide adenine dinucleotide phosphate - reduced[c] '''<=>''' 1.0 5,6,7,8-Tetrahydrofolate[c] '''+''' 1.0 Nicotinamide adenine dinucleotide phosphate[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* [[EF3178]]
+
* Gene: [[EF1577]]
−
** [[pantograph]]-[[l_plantarum_wcfs1]]
+
** Source: [[orthology-l_plantarum_wcfs1]]
−
** [[pantograph]]-[[e_coli_sstr_k12_substr_mg1655]]
+
** Source: [[orthology-e_coli_sstr_k12_substr_mg1655]]
−
** [[pantograph]]-[[b_subtilis_subsp_subtilis_str168]]
+
** Source: [[orthology-b_subtilis_subsp_subtilis_str168]]
 
== Pathways  ==
 
== Pathways  ==
 
* [[map01100]]: [http://www.genome.jp/dbget-bin/www_bget?map01100 map01100]
 
* [[map01100]]: [http://www.genome.jp/dbget-bin/www_bget?map01100 map01100]
 
** '''460''' reactions found over '''2349''' reactions in the full pathway
 
** '''460''' reactions found over '''2349''' reactions in the full pathway
−
* [[map01230]]: [http://www.genome.jp/dbget-bin/www_bget?map01230 map01230]
+
* [[map00670]]: [http://www.genome.jp/dbget-bin/www_bget?map00670 map00670]
−
** '''56''' reactions found over '''228''' reactions in the full pathway
+
** '''14''' reactions found over '''65''' reactions in the full pathway
−
* [[map01120]]: [http://www.genome.jp/dbget-bin/www_bget?map01120 map01120]
+
* [[map00790]]: [http://www.genome.jp/dbget-bin/www_bget?map00790 map00790]
−
** '''104''' reactions found over '''715''' reactions in the full pathway
+
** '''12''' reactions found over '''41''' reactions in the full pathway
−
* [[map00300]]: [http://www.genome.jp/dbget-bin/www_bget?map00300 map00300]
+
−
** '''13''' reactions found over '''34''' reactions in the full pathway
+
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[orthology]]
 
* Category: [[orthology]]
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== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=22608 22608]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=15009 15009]
−
* BioCyc : META:SUCCDIAMINOPIMDESUCC-RXN
+
* Reactome : REACT_R-BTA-197972
−
* MetaNetX (MNX) Equation : MNXR104300
+
* MetaNetX (MNX) Equation : MNXR97401
−
* KEGG Reaction : R02734
+
* KEGG Reaction : R00939
−
* EC Number : 3.5.1.18
+
* EC Number : 1.5.1.3
−
{{#set: direction=LEFT-TO-RIGHT}}
+
{{#set: direction=REVERSIBLE}}
−
{{#set: common name=Succinyl-diaminopimelate desuccinylase}}
+
{{#set: common name=Dihydrofolate reductase}}
−
{{#set: gene associated=EF3178}}
+
{{#set: gene associated=EF1577}}
−
{{#set: in pathway=map01100|map01230|map01120|map00300}}
+
{{#set: in pathway=map01100|map00670|map00790}}
 
{{#set: reconstruction category=orthology}}
 
{{#set: reconstruction category=orthology}}
 
{{#set: reconstruction source=orthology-e_coli_sstr_k12_substr_mg1655|orthology-b_subtilis_subsp_subtilis_str168|orthology-l_plantarum_wcfs1}}
 
{{#set: reconstruction source=orthology-e_coli_sstr_k12_substr_mg1655|orthology-b_subtilis_subsp_subtilis_str168|orthology-l_plantarum_wcfs1}}
 
{{#set: reconstruction tool=pantograph}}
 
{{#set: reconstruction tool=pantograph}}

Latest revision as of 16:33, 21 March 2018

Reaction DHFR

  • direction:
    • REVERSIBLE
  • common name:
    • Dihydrofolate reductase
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1.0 H+[c] + 1.0 7,8-Dihydrofolate[c] + 1.0 Nicotinamide adenine dinucleotide phosphate - reduced[c] <=> 1.0 5,6,7,8-Tetrahydrofolate[c] + 1.0 Nicotinamide adenine dinucleotide phosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

Reconstruction information

External links

  • RHEA:
  • Reactome : REACT_R-BTA-197972
  • MetaNetX (MNX) Equation : MNXR97401
  • KEGG Reaction : R00939
  • EC Number : 1.5.1.3




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