3-DEHYDROSPHINGANINE-REDUCTASE-RXN

Reaction 3-DEHYDROSPHINGANINE-REDUCTASE-RXN

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-1.1.1.102
• common name:
  • 3-ketodihydrosphingosine reductase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 DEHYDROSPHINGANINE[c] + 1 NADPH[c] + 1 PROTON[c] => 1 CPD-13612[c] + 1 NADP[c]
• With common name(s):
  • 1 3-dehydrosphinganine[c] + 1 NADPH[c] + 1 H+[c] => 1 D-erythro-sphinganine[c] + 1 NADP+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ12778
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-nannochloropsis_salina

Pathways

• PWY-5129, sphingolipid biosynthesis (plants): PWY-5129
  • 4 reactions found over 13 reactions in the full pathway
• SPHINGOLIPID-SYN-PWY, sphingolipid biosynthesis (yeast): SPHINGOLIPID-SYN-PWY
  • 4 reactions found over 8 reactions in the full pathway
• PWY3DJ-12, ceramide de novo biosynthesis: PWY3DJ-12
  • 2 reactions found over 4 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 22642
• LIGAND-RXN:
  • R02978