3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN

Reaction 3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-3.1.2.4
• common name:
  • 3-hydroxyisobutyryl-CoA hydrolase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CPD-12173[c] + 1 WATER[c] => 1 CPD-12175[c] + 1 PROTON[c] + 1 CO-A[c]
• With common name(s):
  • 1 (S)-3-hydroxy-isobutanoyl-CoA[c] + 1 H2O[c] => 1 (S)-3-hydroxy-isobutanoate[c] + 1 H+[c] + 1 coenzyme A[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ16590
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ21390
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ22164
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ00040
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ11169
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ22166
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-nannochloropsis_salina
• Gene: SJ04418
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ14130
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ14591
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ03913
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ07211
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM

Pathways

• VALDEG-PWY, L-valine degradation I: VALDEG-PWY
  • 6 reactions found over 8 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 20889
• LIGAND-RXN:
  • R03352
  • R05064